Critical role of Syk-dependent STAT1 activation in innate antiviral immunity

Influenza Virus-Induced Robust Expression of SOCS3 Contributes to Excessive Production of IL-6

(2019) Shasha Liu et al.   Frontiers in Immunology

Regulation of MAVS activation through post-translational modifications

(2018) Bingyu Liu et al.   CURRENT OPINION IN IMMUNOLOGY

Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS

(2018) Tianzi Liuyu et al.   CELL RESEARCH

Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease

(2017) Prajwal Gurung et al.   IMMUNITY

Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness

(2017) Ioanna E. Galani et al.   IMMUNITY

Tofacitinib or Adalimumab versus Placebo for Psoriatic Arthritis

(2017) Philip Mease et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epidemiology, Evolution, and Pathogenesis of H7N9 Influenza Viruses in Five Epidemic Waves since 2013 in China

(2017) Shuo Su et al.   TRENDS IN MICROBIOLOGY

Antagonizing Integrin  3 Increases Immunosuppression in Cancer

(2016) X. Su et al.   CANCER RESEARCH

Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling

(2016) Alesha Grant et al.   Cell Host & Microbe

Response to interferons and antibacterial innate immunity in the absence of tyrosine‐phosphorylated STAT1

(2016) Andrea Majoros et al.   EMBO REPORTS

RIG-I-like receptor regulation in virus infection and immunity

(2015) Ying Kai Chan et al.   Current Opinion in Virology

How RIG-I like receptors activate MAVS

(2015) Bin Wu et al.   Current Opinion in Virology

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

NRAV, a Long Noncoding RNA, Modulates Antiviral Responses through Suppression of Interferon-Stimulated Gene Transcription

(2014) Jing Ouyang et al.   Cell Host & Microbe

Mechanisms of Jak/STAT Signaling in Immunity and Disease

(2014) Alejandro V. Villarino et al.   JOURNAL OF IMMUNOLOGY

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates

(2014) Delphine Goubau et al.   NATURE

An ITAM-Syk-CARD9 signalling axis triggers contact hypersensitivity by stimulating IL-1 production in dendritic cells

(2014) Shinsuke Yasukawa et al.   Nature Communications

Suppression of Interferon Lambda Signaling by SOCS-1 Results in Their Excessive Production during Influenza Virus Infection

(2014) Haitao Wei et al.   PLoS Pathogens

Hepatic RIG-I Predicts Survival and Interferon-α Therapeutic Response in Hepatocellular Carcinoma

(2013) Jin Hou et al.   CANCER CELL

eIF4B Phosphorylation by Pim Kinases Plays a Critical Role in Cellular Transformation by Abl Oncogenes

(2013) J. Yang et al.   CANCER RESEARCH

Generating rats with conditional alleles using CRISPR/Cas9

(2013) Yuanwu Ma et al.   CELL RESEARCH

Synergistic Expression of the CXCL10 Gene in Response to IL-1  and IFN-  Involves NF- B, Phosphorylation of STAT1 at Tyr701, and Acetylation of Histones H3 and H4

(2013) S. J. Burke et al.   JOURNAL OF IMMUNOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Transport of Influenza Virus Neuraminidase (NA) to Host Cell Surface Is Regulated by ARHGAP21 and Cdc42 Proteins

(2012) Song Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Double-Stranded RNA Induces Biphasic STAT1 Phosphorylation by both Type I Interferon (IFN)-Dependent and Type I IFN-Independent Pathways

(2012) J. Dempoya et al.   JOURNAL OF VIROLOGY

Inhibition of Src Family Kinases and Receptor Tyrosine Kinases by Dasatinib: Possible Combinations in Solid Tumors

(2011) J. C. Montero et al.   CLINICAL CANCER RESEARCH

Mapping a Dynamic Innate Immunity Protein Interaction Network Regulating Type I Interferon Production

(2011) Shitao Li et al.   IMMUNITY

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Sensing and Signaling in Antiviral Innate Immunity

(2010) Luke A.J. O'Neill et al.   CURRENT BIOLOGY

Transcription Factor Redundancy Ensures Induction of the Antiviral State

(2010) Sonja Schmid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SARS-CoV Pathogenesis Is Regulated by a STAT1 Dependent but a Type I, II and III Interferon Receptor Independent Mechanism

(2010) Matthew B. Frieman et al.   PLoS Pathogens

CLEC5A is critical for dengue-virus-induced lethal disease

(2008) Szu-Ting Chen et al.   NATURE