标题
Environment‐Responsive Lipid/siRNA Nanoparticles for Cancer Therapy
作者
关键词
-
出版物
Advanced Healthcare Materials
Volume -, Issue -, Pages 2001294
出版商
Wiley
发表日期
2020-12-04
DOI
10.1002/adhm.202001294
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- A Combinatorial Library of Lipid Nanoparticles for RNA Delivery to Leukocytes
- (2020) Srinivas Ramishetti et al. ADVANCED MATERIALS
- Charge-reversible Lipid Derivative: A Novel Type of pH-responsive Lipid for Nanoparticle-mediated siRNA Delivery
- (2020) Yusuke Hirai et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Monoclonal Antibody 2C5-Modified Mixed Dendrimer Micelles for Tumor-Targeted Codelivery of Chemotherapeutics and siRNA
- (2020) Jiayi Pan et al. MOLECULAR PHARMACEUTICS
- Generation and validation of structurally defined antibody–siRNA conjugates
- (2020) Alex R Nanna et al. NUCLEIC ACIDS RESEARCH
- Recent Advances of Polycationic siRNA Vectors for Cancer Therapy
- (2020) Raut Bholakant et al. BIOMACROMOLECULES
- Gene Therapy Intervention in Neovascular Eye Disease: A Recent Update
- (2020) Fan-Li Lin et al. MOLECULAR THERAPY
- Nanoparticle-siRNA: A potential strategy for rheumatoid arthritis therapy?
- (2020) Naibo Feng et al. JOURNAL OF CONTROLLED RELEASE
- An Open‐Label, Multicenter, Phase I, Dose Escalation Study with Phase II Expansion Cohort to Determine the Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Intravenous TKM‐080301 in Subjects with Advanced Hepatocellular Carcinoma
- (2019) Imane El Dika et al. ONCOLOGIST
- Cationic Niosomes as Non-Viral Vehicles for Nucleic Acids: Challenges and Opportunities in Gene Delivery
- (2019) Santiago Grijalvo et al. Pharmaceutics
- Understanding structure-activity relationships of pH-sensitive cationic lipids facilitates the rational identification of promising lipid nanoparticles for delivering siRNAs in vivo
- (2019) Yusuke Sato et al. JOURNAL OF CONTROLLED RELEASE
- Systemic Delivery of Tumor-Targeting siRNA Nanoparticles against an Oncogenic LncRNA Facilitates Effective Triple-Negative Breast Cancer Therapy
- (2019) Amita M Vaidya et al. BIOCONJUGATE CHEMISTRY
- Binary Targeting of siRNA to Hematologic Cancer Cells In Vivo Using Layer‐by‐Layer Nanoparticles
- (2019) Ki Young Choi et al. ADVANCED FUNCTIONAL MATERIALS
- Lung-Endothelium-Targeted Nanoparticles Based on a pH-Sensitive Lipid and the GALA Peptide Enable Robust Gene Silencing and the Regression of Metastatic Lung Cancer
- (2019) Mahmoud M. Abd Elwakil et al. ADVANCED FUNCTIONAL MATERIALS
- Lipid-Based DNA Therapeutics – Hallmarks of Non-Viral Gene Delivery
- (2019) Jonas Buck et al. ACS Nano
- Small interfering RNAs (siRNAs) in cancer therapy: a nano-based approach
- (2019) Ghanbar Mahmoodi Chalbatani et al. International Journal of Nanomedicine
- Lipid Nanoparticles for Delivery of Therapeutic RNA Oligonucleotides
- (2019) Keith Henry Moss et al. MOLECULAR PHARMACEUTICS
- Formulation of Biocompatible Targeted ECO/siRNA Nanoparticles with Long-Term Stability for Clinical Translation of RNAi
- (2019) Nadia R. Ayat et al. Nucleic Acid Therapeutics
- Design of a Novel PEGylated Liposomal Vector for Systemic Delivery of siRNA to Solid Tumors
- (2019) Furan Song et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Gene Therapy Tools for Brain Diseases
- (2019) Selene Ingusci et al. Frontiers in Pharmacology
- Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics
- (2019) Jayesh A. Kulkarni et al. ACCOUNTS OF CHEMICAL RESEARCH
- A Multifunctional Lipid-Based Nanodevice for the Highly Specific Codelivery of Sorafenib and Midkine siRNA to Hepatic Cancer Cells
- (2019) Mahmoud A. Younis et al. MOLECULAR PHARMACEUTICS
- Effect of the Ratio of Betamethasone to TNF-α siRNA Coencapsulated in Solid Lipid Nanoparticles on the Acute Proinflammatory Activity of the Nanoparticles
- (2019) Hannah L. O’Mary et al. MOLECULAR PHARMACEUTICS
- Binding and Internalization in Receptor‐Targeted Carriers: The Complex Role of CD44 in the Uptake of Hyaluronic Acid‐Based Nanoparticles (siRNA Delivery)
- (2019) Julio M. Rios de la Rosa et al. Advanced Healthcare Materials
- The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs
- (2019) Akin Akinc et al. Nature Nanotechnology
- On the Formation and Morphology of Lipid Nanoparticles Containing Ionizable Cationic Lipids and siRNA
- (2018) Jayesh A. Kulkarni et al. ACS Nano
- Rationally Designed Polycationic Carriers for Potent Polymeric siRNA-Mediated Gene Silencing
- (2018) Connie Wu et al. ACS Nano
- Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo
- (2018) Philipp Michael Klein et al. BIOMATERIALS
- Effect of cationic lipid in cationic liposomes on siRNA delivery into the lung by intravenous injection of cationic lipoplex
- (2018) Yoshiyuki Hattori et al. JOURNAL OF DRUG TARGETING
- Drug Delivery in Cancer Therapy, Quo Vadis?
- (2018) Zheng-Rong Lu et al. MOLECULAR PHARMACEUTICS
- A review on current status of antiviral siRNA
- (2018) Abid Qureshi et al. REVIEWS IN MEDICAL VIROLOGY
- Transfection by cationic gemini lipids and surfactants
- (2018) M. Damen et al. MedChemComm
- Lipid Nanoparticles Enabling Gene Therapies: From Concepts to Clinical Utility
- (2018) Jayesh A. Kulkarni et al. Nucleic Acid Therapeutics
- Cationic Hyperbranched Polymers with Biocompatible Shells for siRNA Delivery
- (2018) Sipei Li et al. BIOMACROMOLECULES
- Patisiran: First Global Approval
- (2018) Sheridan M. Hoy DRUGS
- Mixing lipids to manipulate the ionization status of lipid nanoparticles for specific tissue targeting
- (2018) Nour Shobaki et al. International Journal of Nanomedicine
- Self-Assembled Nanostructured Lipid Systems: Is There a Link between Structure and Cytotoxicity?
- (2018) Angel Tan et al. Advanced Science
- Effective Therapy Using a Liposomal siRNA that Targets the Tumor Vasculature in a Model Murine Breast Cancer with Lung Metastasis
- (2018) Yu Sakurai et al. Molecular Therapy-Oncolytics
- Hypoxia-responsive ionizable liposome delivery siRNA for glioma therapy
- (2017) Hong-Mei Liu et al. International Journal of Nanomedicine
- Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases
- (2017) Christos Tapeinos et al. JOURNAL OF CONTROLLED RELEASE
- Modality of tumor endothelial VEGFR2 silencing-mediated improvement in intratumoral distribution of lipid nanoparticles
- (2017) Shoshiro Yamamoto et al. JOURNAL OF CONTROLLED RELEASE
- Preclinical Mammalian Safety Studies of EPHARNA (DOPC Nanoliposomal EphA2-Targeted siRNA)
- (2017) Michael J. Wagner et al. MOLECULAR CANCER THERAPEUTICS
- Lipid Nanoparticle Systems for Enabling Gene Therapies
- (2017) Pieter R. Cullis et al. MOLECULAR THERAPY
- Liposome-polyethylenimine complexes (DPPC-PEI lipopolyplexes) for therapeutic siRNA delivery in vivo
- (2017) Alexander Ewe et al. Nanomedicine-Nanotechnology Biology and Medicine
- Cationic switchable lipids: pH-triggered molecular switch for siRNA delivery
- (2017) W. Viricel et al. Nanoscale
- Overcoming cellular barriers for RNA therapeutics
- (2017) Steven F Dowdy NATURE BIOTECHNOLOGY
- Stimuli-responsive liposomes for drug delivery
- (2017) Y. Lee et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Advances in siRNA delivery in cancer therapy
- (2017) Aishwarya Singh et al. Artificial Cells Nanomedicine and Biotechnology
- Targeted Multifunctional Lipid ECO Plasmid DNA Nanoparticles as Efficient Non-viral Gene Therapy for Leber’s Congenital Amaurosis
- (2017) Da Sun et al. Molecular Therapy-Nucleic Acids
- The role of helper lipids in lipid nanoparticles (LNPs) designed for oligonucleotide delivery
- (2016) Xinwei Cheng et al. ADVANCED DRUG DELIVERY REVIEWS
- Effect of surface properties on liposomal siRNA delivery
- (2016) Yuqiong Xia et al. BIOMATERIALS
- A phase Ib/IIa study of combination therapy with gemcitabine and Atu027 in patients with locally advanced or metastatic pancreatic adenocarcinoma.
- (2016) Beate Schultheis et al. JOURNAL OF CLINICAL ONCOLOGY
- One-step encapsulation of siRNA between lipid-layers of multi-layer polycation liposomes by lipoplex freeze-thawing
- (2016) Hiroyuki Koide et al. JOURNAL OF CONTROLLED RELEASE
- A lipid nanoparticle for the efficient delivery of siRNA to dendritic cells
- (2016) Shota Warashina et al. JOURNAL OF CONTROLLED RELEASE
- Design of Ionizable Lipids To Overcome the Limiting Step of Endosomal Escape: Application in the Intracellular Delivery of mRNA, DNA, and siRNA
- (2016) Damien Habrant et al. JOURNAL OF MEDICINAL CHEMISTRY
- Relationship Between the Physicochemical Properties of Lipid Nanoparticles and the Quality of siRNA Delivery to Liver Cells
- (2016) Yusuke Sato et al. MOLECULAR THERAPY
- Remodeling of the Extracellular Matrix by Endothelial Cell-Targeting siRNA Improves the EPR-Based Delivery of 100 nm Particles
- (2016) Yu Sakurai et al. MOLECULAR THERAPY
- Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression
- (2016) Jesse M. Engreitz et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Targeted Dual pH-Sensitive Lipid ECO/siRNA Self-Assembly Nanoparticles Facilitate In Vivo Cytosolic sieIF4E Delivery and Overcome Paclitaxel Resistance in Breast Cancer Therapy
- (2016) Maneesh Gujrati et al. Advanced Healthcare Materials
- Switchable Lipids: Conformational Change for Fast pH-Triggered Cytoplasmic Delivery
- (2015) Warren Viricel et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Multifunctional pH-Sensitive Amino Lipids for siRNA Delivery
- (2015) Maneesh Gujrati et al. BIOCONJUGATE CHEMISTRY
- Silencing β3 Integrin by Targeted ECO/siRNA Nanoparticles Inhibits EMT and Metastasis of Triple-Negative Breast Cancer
- (2015) Jenny G. Parvani et al. CANCER RESEARCH
- siRNA Lipid Nanoparticle Potently Silences Clusterin and Delays Progression When Combined with Androgen Receptor Cotargeting in Enzalutamide-Resistant Prostate Cancer
- (2015) Y. Yamamoto et al. CLINICAL CANCER RESEARCH
- Gene silencing: a therapeutic approach to combat influenza virus infections
- (2015) Madhu Khanna et al. Future Microbiology
- RNA interference targeting hypoxia-inducible factor 1α via a novel multifunctional surfactant attenuates glioma growth in an intracranial mouse model
- (2015) David L. Gillespie et al. JOURNAL OF NEUROSURGERY
- Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown
- (2015) Anders Wittrup et al. NATURE BIOTECHNOLOGY
- The emerging role of lncRNAs in cancer
- (2015) Maite Huarte NATURE MEDICINE
- Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study
- (2015) Ole B Suhr et al. Orphanet Journal of Rare Diseases
- Targeting Polo-Like Kinases: A Promising Therapeutic Approach for Cancer Treatment
- (2015) Xiaoqi Liu Translational Oncology
- First-in-Human Phase I Study of the Liposomal RNA Interference Therapeutic Atu027 in Patients With Advanced Solid Tumors
- (2014) Beate Schultheis et al. JOURNAL OF CLINICAL ONCOLOGY
- Multifunctional Cationic Lipid-Based Nanoparticles Facilitate Endosomal Escape and Reduction-Triggered Cytosolic siRNA Release
- (2014) Maneesh Gujrati et al. MOLECULAR PHARMACEUTICS
- Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases
- (2014) Yadong Huang et al. NEUROBIOLOGY OF DISEASE
- Cationic liposome–nucleic acid complexes for gene delivery and gene silencing
- (2014) Cyrus R. Safinya et al. NEW JOURNAL OF CHEMISTRY
- The Role of the Helper Lipid on the DNA Transfection Efficiency of Lipopolyplex Formulations
- (2014) Zixiu Du et al. Scientific Reports
- Design, preparation and application of nucleic acid delivery carriers
- (2013) Jun Yang et al. BIOTECHNOLOGY ADVANCES
- Small-interfering RNAs (siRNAs) as a promising tool for ocular therapy
- (2013) A Guzman-Aranguez et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cotargeting Androgen Receptor and Clusterin Delays Castrate-Resistant Prostate Cancer Progression by Inhibiting Adaptive Stress Response and AR Stability
- (2013) H. Matsumoto et al. CANCER RESEARCH
- Formulation development of lyophilized, long-term stable siRNA/oligoaminoamide polyplexes
- (2013) Julia Christina Kasper et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Design and evaluation of new pH-sensitive amphiphilic cationic lipids for siRNA delivery
- (2013) Anthony S. Malamas et al. JOURNAL OF CONTROLLED RELEASE
- RNAi-mediated gene knockdown and anti-angiogenic therapy of RCCs using a cyclic RGD-modified liposomal-siRNA system
- (2013) Yu Sakurai et al. JOURNAL OF CONTROLLED RELEASE
- Gene Silencing via RNAi and siRNA Quantification in Tumor Tissue Using MEND, a Liposomal siRNA Delivery System
- (2013) Yu Sakurai et al. MOLECULAR THERAPY
- Delivery materials for siRNA therapeutics
- (2013) Rosemary Kanasty et al. NATURE MATERIALS
- Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis
- (2013) Teresa Coelho et al. NEW ENGLAND JOURNAL OF MEDICINE
- Advances in Lipid Nanoparticles for siRNA Delivery
- (2013) Yuen Tam et al. Pharmaceutics
- A Multifunctional Envelope-type Nanodevice for Use in Nanomedicine: Concept and Applications
- (2012) T. Nakamura et al. ACCOUNTS OF CHEMICAL RESEARCH
- Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo
- (2012) Muthusamy Jayaraman et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Anatomic Distribution of Gadolinium Contrast Medium by High-Resolution Magnetic Resonance Imaging After Peribulbar and Retrobulbar Injections
- (2012) David R. P. Almeida et al. ARCHIVES OF OPHTHALMOLOGY
- A pH-sensitive cationic lipid facilitates the delivery of liposomal siRNA and gene silencing activity in vitro and in vivo
- (2012) Yusuke Sato et al. JOURNAL OF CONTROLLED RELEASE
- Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core
- (2012) Alex K. K. Leung et al. Journal of Physical Chemistry C
- Action and Reaction: The Biological Response to siRNA and Its Delivery Vehicles
- (2012) Rosemary L Kanasty et al. MOLECULAR THERAPY
- The hallmarks of cancer
- (2012) Tony Gutschner et al. RNA Biology
- Non-Viral Nucleic Acid Delivery: Key Challenges and Future Directions
- (2012) Mahmoud Elsabahy et al. Current Drug Delivery
- Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA
- (2012) Nathan M Belliveau et al. Molecular Therapy-Nucleic Acids
- Dicetyl Phosphate-Tetraethylenepentamine-Based Liposomes for Systemic siRNA Delivery
- (2011) Tomohiro Asai et al. BIOCONJUGATE CHEMISTRY
- Lipid nanoparticle siRNA systems for silencing the androgen receptor in human prostate cancer in vivo
- (2011) Justin B. Lee et al. INTERNATIONAL JOURNAL OF CANCER
- Versatile cationic lipids for siRNA delivery
- (2011) Jeff Sparks et al. JOURNAL OF CONTROLLED RELEASE
- Ionization Behavior of Amino Lipids for siRNA Delivery: Determination of Ionization Constants, SAR, and the Impact of Lipid pKaon Cationic Lipid−Biomembrane Interactions
- (2011) Jingtao Zhang et al. LANGMUIR
- Cationic liposome–nucleic acid complexes: liquid crystal phases with applications in gene therapy
- (2011) C.R. Safinya et al. LIQUID CRYSTALS
- Silencing or Stimulation? siRNA Delivery and the Immune System
- (2011) Kathryn A. Whitehead et al. Annual Review of Chemical and Biomolecular Engineering
- A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: A strategy for overcoming the PEG dilemma
- (2010) Hiroto Hatakeyama et al. ADVANCED DRUG DELIVERY REVIEWS
- RNAi therapeutics for CNS disorders
- (2010) Ryan L. Boudreau et al. BRAIN RESEARCH
- Targeting the eIF4F translation initiation complex for cancer therapy
- (2010) Bruce W. Konicek et al. CELL CYCLE
- Atu027 Prevents Pulmonary Metastasis in Experimental and Spontaneous Mouse Metastasis Models
- (2010) A. Santel et al. CLINICAL CANCER RESEARCH
- Polyethylenimines for RNAi-mediated gene targeting in vivo and siRNA delivery to the lung
- (2010) Melanie Günther et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Emerging strategies for EphA2 receptor targeting for cancer therapeutics
- (2010) Manish Tandon et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation☆
- (2010) Hidetaka Akita et al. JOURNAL OF CONTROLLED RELEASE
- Endosomal escape pathways for delivery of biologicals
- (2010) Amir K. Varkouhi et al. JOURNAL OF CONTROLLED RELEASE
- New Amphiphilic Carriers Forming pH-Sensitive Nanoparticles for Nucleic Acid Delivery
- (2010) Rongzuo Xu et al. LANGMUIR
- Rational design of cationic lipids for siRNA delivery
- (2010) Sean C Semple et al. NATURE BIOTECHNOLOGY
- Lipid-like materials for low-dose, in vivo gene silencing
- (2010) K. T. Love et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Efficient Short Interference RNA Delivery to Tumor Cells Using a Combination of Octaarginine, GALA and Tumor-Specific, Cleavable Polyethylene Glycol System
- (2009) Yu Sakurai et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Lipid-based nanotherapeutics for siRNA delivery
- (2009) A. Schroeder et al. JOURNAL OF INTERNAL MEDICINE
- An Architectural Role for a Nuclear Noncoding RNA: NEAT1 RNA Is Essential for the Structure of Paraspeckles
- (2009) Christine M. Clemson et al. MOLECULAR CELL
- The First Targeted Delivery of siRNA in Humans via a Self-Assembling, Cyclodextrin Polymer-Based Nanoparticle: From Concept to Clinic
- (2009) Mark E. Davis MOLECULAR PHARMACEUTICS
- Targeted Systemic Delivery of a Therapeutic siRNA with a Multifunctional Carrier Controls Tumor Proliferation in Mice
- (2009) Xu-Li Wang et al. MOLECULAR PHARMACEUTICS
- Evaluation of cationic liposomes composed of an amino acid–based lipid for neuronal transfection
- (2009) Yosuke Obata et al. Nanomedicine-Nanotechnology Biology and Medicine
- Long non-coding RNAs: insights into functions
- (2009) Tim R. Mercer et al. NATURE REVIEWS GENETICS
- Atu027, a Liposomal Small Interfering RNA Formulation Targeting Protein Kinase N3, Inhibits Cancer Progression
- (2008) M. Aleku et al. CANCER RESEARCH
- Recent progress in tumor pH targeting nanotechnology
- (2008) Eun Seong Lee et al. JOURNAL OF CONTROLLED RELEASE
- A peptide-targeted delivery system with pH-sensitive amphiphilic cell membrane disruption for efficient receptor-mediated siRNA delivery
- (2008) Xu-Li Wang et al. JOURNAL OF CONTROLLED RELEASE
- A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
- (2008) Akin Akinc et al. NATURE BIOTECHNOLOGY
- A multifunctional and reversibly polymerizable carrier for efficient siRNA delivery
- (2007) Xu-Li Wang et al. BIOMATERIALS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started