Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies

Pig-to-non-human primate heart transplantation: the final step toward clinical xenotransplantation?

(2020) Bruno Reichart et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Functional changes of the liver in the absence of growth hormone (GH) action – Proteomic and metabolomic insights from a GH receptor deficient pig model

(2020) Evamaria O. Riedel et al.   Molecular Metabolism

Xeno-organ donor pigs with multiple genetic modifications – the more the better?

(2020) Elisabeth Kemter et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Effects of tissue-specific GH receptor knockouts in mice

(2020) Edward O. List et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Hemodynamic evaluation of anesthetized baboons and piglets by transpulmonary thermodilution: Normal values and interspecies differences with respect to xenotransplantation

(2019) Matthias Längin et al.   XENOTRANSPLANTATION

Linkage between growth retardation and pituitary cell morphology in a dystrophin-deficient pig model of Duchenne muscular dystrophy

(2019) I. Hofmann et al.   GROWTH HORMONE & IGF RESEARCH

MECHANISMS IN ENDOCRINOLOGY: Lessons from growth hormone receptor gene-disrupted mice: are there benefits of endocrine defects?

(2018) Reetobrata Basu et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver

(2018) Arne Hinrichs et al.   Molecular Metabolism

Growth hormone deficiency: health and longevity

(2018) Manuel H Aguiar-Oliveira et al.   ENDOCRINE REVIEWS

Consistent success in life-supporting porcine cardiac xenotransplantation

(2018) Matthias Längin et al.   NATURE

The causes and consequences of pituitary gigantism

(2018) Albert Beckers et al.   Nature Reviews Endocrinology

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Immunological and physiological observations in baboons with life-supporting genetically engineered pig kidney grafts

(2017) Hayato Iwase et al.   XENOTRANSPLANTATION

The Munich MIDY Pig Biobank – A unique resource for studying organ crosstalk in diabetes

(2017) Andreas Blutke et al.   Molecular Metabolism

Cardiac-Specific Disruption of GH Receptor Alters Glucose Homeostasis While Maintaining Normal Cardiac Performance in Adult Male Mice

(2016) Adam Jara et al.   ENDOCRINOLOGY

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Tissue Sampling Guides for Porcine Biomedical Models

(2016) Barbara Albl et al.   TOXICOLOGIC PATHOLOGY

Peptidyl-prolyl isomerases: Functionality and potential therapeutic targets in cardiovascular disease

(2015) Muhamad A Rostam et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

LESSONS FROM 50 YEARS OF STUDY OF LARON SYNDROME

(2015) Zvi Laron   Endocrine Practice

Pig kidney graft survival in a baboon for 136 days: longest life-supporting organ graft survival to date

(2015) Hayato Iwase et al.   XENOTRANSPLANTATION

Screening pigs for xenotransplantation: prevalence and expression of porcine endogenous retroviruses in Göttingen minipigs

(2015) Marwan Semaan et al.   XENOTRANSPLANTATION

Reference Intervals for Insulin-like Growth Factor-1 (IGF-I) From Birth to Senescence: Results From a Multicenter Study Using a New Automated Chemiluminescence IGF-I Immunoassay Conforming to Recent International Recommendations

(2014) Martin Bidlingmaier et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ketone body metabolism and its defects

(2014) Toshiyuki Fukao et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

New insights into IGF-1 signaling in the heart

(2014) Rodrigo Troncoso et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Regulatory Sequences of the Porcine THBD Gene Facilitate Endothelial-Specific Expression of Bioactive Human Thrombomodulin in Single- and Multitransgenic Pigs

(2013) Annegret Wuensch et al.   TRANSPLANTATION

Nucleosome assembly proteins and their interacting proteins in neuronal differentiation

(2012) Mikaël Attia et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Xenografted Islet Cell Clusters From INSLEA29Y Transgenic Pigs Rescue Diabetes and Prevent Immune Rejection in Humanized Mice

(2012) N. Klymiuk et al.   DIABETES

The many roles of the eukaryotic elongation factor 1 complex

(2012) Arjun N. Sasikumar et al.   Wiley Interdisciplinary Reviews-RNA

Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans

(2011) J. Guevara-Aguirre et al.   Science Translational Medicine

The Intricate Role of Growth Hormone in Metabolism

(2011) Archana Vijayakumar et al.   Frontiers in Endocrinology

Review: NAD + : A modulator of immune functions

(2010) Andreas Grahnert et al.   Innate Immunity

Characterization of a CD46 transgenic pig and protection of transgenic kidneys against hyperacute rejection in non-immunosuppressed baboons

(2010) Bruce E. Loveland et al.   XENOTRANSPLANTATION

Biological effects of growth hormone on carbohydrate and lipid metabolism

(2009) Archana Vijayakumar et al.   GROWTH HORMONE & IGF RESEARCH