Activation of NLRP3 inflammasome in hepatocytes after exposure to cobalt nanoparticles: The role of oxidative stress

Inflammasome‐associated cell death: Pyroptosis, apoptosis, and physiological implications

(2020) Kohsuke Tsuchiya   MICROBIOLOGY AND IMMUNOLOGY

Targeted T1 Magnetic Resonance Imaging Contrast Enhancement with Extraordinarily Small CoFe2O4 Nanoparticles

(2019) Dominique Piché et al.   ACS Applied Materials & Interfaces

Innate immune cells orchestrate the repair of sterile injury in the liver and beyond

(2019) Mokarram Hossain et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nanoparticle translocation and multi-organ toxicity: A particularly small problem

(2019) Jennifer B. Raftis et al.   Nano Today

Co Nanoislands Rooted on Co–N–C Nanosheets as Efficient Oxygen Electrocatalyst for Zn–Air Batteries

(2019) Peng Yu et al.   ADVANCED MATERIALS

A human whole-blood model to study the activation of innate immunity system triggered by nanoparticles as a demonstrator for toxicity

(2019) Kristina N Ekdahl et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Translocation of transition metal oxide nanoparticles to breast milk and offspring: The necessity of bridging mother-offspring-integration toxicological assessments

(2019) Jie Cai et al.   ENVIRONMENT INTERNATIONAL

Toxicological Profiling of Metal Oxide Nanoparticles in Liver Context Reveals Pyroptosis in Kupffer Cells and Macrophages versus Apoptosis in Hepatocytes

(2018) Vahid Mirshafiee et al.   ACS Nano

Mitochondria, the NLRP3 Inflammasome, and Sirtuins in Type 2 Diabetes: New Therapeutic Targets

(2018) Susana Rovira-Llopis et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanistic insight into reactivity and (geno)toxicity of well-characterized nanoparticles of cobalt metal and oxides

(2018) Francesca Cappellini et al.   Nanotoxicology

Melatonin alleviates cadmium-induced liver injury by inhibiting the TXNIP-NLRP3 inflammasome

(2017) Zhengwang Cao et al.   JOURNAL OF PINEAL RESEARCH

Cobalt nanoparticles induce lung injury, DNA damage and mutations in mice

(2017) Rong Wan et al.   Particle and Fibre Toxicology

Phagolysosome acidification is required for silica and engineered nanoparticle-induced lysosome membrane permeabilization and resultant NLRP3 inflammasome activity

(2017) Forrest Jessop et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Reactive oxygen species trigger NF-κB-mediated NLRP3 inflammasome activation induced by zinc oxide nanoparticles in A549 cells

(2017) Xiao Liang et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Oral uptake of nanoparticles: human relevance and the role of in vitro systems

(2016) Eleonore Fröhlich et al.   ARCHIVES OF TOXICOLOGY

CdSe/ZnS quantum dots induce hepatocyte pyroptosis and liver inflammation via NLRP3 inflammasome activation

(2016) Yonghui Lu et al.   BIOMATERIALS

Occupational dermal exposure to nanoparticles and nano-enabled products: Part I—Factors affecting skin absorption

(2016) Francesca Larese Filon et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Exposure to nickel oxide nanoparticles induces pulmonary inflammation through NLRP3 inflammasome activation in rats

(2016) Zhengwang Cao et al.   International Journal of Nanomedicine

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

Air- and Water-Resistant Noble Metal Coated Ferromagnetic Cobalt Nanorods

(2015) Sergio Lentijo-Mozo et al.   ACS Nano

Reactive Oxygen Species-Induced TXNIP Drives Fructose-Mediated Hepatic Inflammation and Lipid Accumulation Through NLRP3 Inflammasome Activation

(2015) Xian Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Toxicity of cobalt oxide nanoparticles to normal cells; an in vitro and in vivo study

(2015) Sourav Chattopadhyay et al.   CHEMICO-BIOLOGICAL INTERACTIONS

NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes

(2015) Bingbing Sun et al.   Small

The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine

(2015) L Baron et al.   Cell Death & Disease

K+ regulates Ca2+ to drive inflammasome signaling: dynamic visualization of ion flux in live cells

(2015) J R Yaron et al.   Cell Death & Disease

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

(2015) Amna Abderrazak et al.   Redox Biology

A Smart Platform for Hyperthermia Application in Cancer Treatment: Cobalt-Doped Ferrite Nanoparticles Mineralized in Human Ferritin Cages

(2014) Elvira Fantechi et al.   ACS Nano

Reactive oxygen species-related activities of nano-iron metal and nano-iron oxides

(2014) Haohao Wu et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

(2014) Alberto Baroja-Mazo et al.   NATURE IMMUNOLOGY

Activation of NLRP3 inflammasome by crystalline structures via cell surface contact

(2014) Aswin Hari et al.   Scientific Reports

Up-regulation of Gadd45α after exposure to metal nanoparticles: The role of hypoxia inducible factor 1α

(2013) Lingfang Feng et al.   ENVIRONMENTAL TOXICOLOGY

NLRP3 inflammasome activation in d-galactosamine and lipopolysaccharide-induced acute liver failure: Role of heme oxygenase-1

(2013) Seok-Joo Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

(2013) Alexander Wree et al.   HEPATOLOGY

Mitochondrial Reactive Oxygen Species Induces NLRP3-Dependent Lysosomal Damage and Inflammasome Activation

(2013) M. E. Heid et al.   JOURNAL OF IMMUNOLOGY

Activation of NLRP3 Inflammasome in Alveolar Macrophages Contributes to Mechanical Stretch-Induced Lung Inflammation and Injury

(2013) J. Wu et al.   JOURNAL OF IMMUNOLOGY

Human Fetal Hepatocyte Line, L-02, Exhibits Good Liver Function In Vitro and in an Acute Liver Failure Model

(2013) X. Hu et al.   TRANSPLANTATION PROCEEDINGS

Inflammasome formation and IL-1β release by human blood monocytes in response to silver nanoparticles

(2012) Eun-Jeong Yang et al.   BIOMATERIALS

DNA Damage Caused by Metal Nanoparticles: Involvement of Oxidative Stress and Activation of ATM

(2012) Rong Wan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Inflammasomes in liver diseases

(2012) Gyongyi Szabo et al.   JOURNAL OF HEPATOLOGY

Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis

(2012) Laura J Dixon et al.   LABORATORY INVESTIGATION

Amino-Functionalized Polystyrene Nanoparticles Activate the NLRP3 Inflammasome in Human Macrophages

(2011) Oleg Lunov et al.   ACS Nano

Effect of Nanoparticles on the Cell Life Cycle

(2011) Morteza Mahmoudi et al.   CHEMICAL REVIEWS

Mitochondria: Sovereign of inflammation?

(2011) Jürg Tschopp   EUROPEAN JOURNAL OF IMMUNOLOGY

Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome

(2011) F. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial Network Determines Intracellular ROS Dynamics and Sensitivity to Oxidative Stress through Switching Inter-Mitochondrial Messengers

(2011) Junseong Park et al.   PLoS One

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1  and IL-1 

(2010) A. S. Yazdi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Mitochondria-Dependent Reactive Oxygen Species-Mediated Programmed Cell Death Induced by 3,3'-Diindolylmethane through Inhibition of F0F1-ATP Synthase in Unicellular Protozoan Parasite Leishmania donovani

(2008) A. Roy et al.   MOLECULAR PHARMACOLOGY

Matrix metalloproteinase-2 and -9 are induced differently by metal nanoparticles in human monocytes: The role of oxidative stress and protein tyrosine kinase activation

(2008) Rong Wan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY