标题
Oral uptake of nanoparticles: human relevance and the role of in vitro systems
作者
关键词
Consumer products, Oro-gastrointestinal tract, Barrier models, Exposure doses, Inter-species differences
出版物
ARCHIVES OF TOXICOLOGY
Volume 90, Issue 10, Pages 2297-2314
出版商
Springer Nature
发表日期
2016-06-26
DOI
10.1007/s00204-016-1765-0
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Modeling Barrier Tissues In Vitro: Methods, Achievements, and Challenges
- (2016) Courtney M. Sakolish et al. EBioMedicine
- Progress and future of in vitro models to study translocation of nanoparticles
- (2015) Hedwig M. Braakhuis et al. ARCHIVES OF TOXICOLOGY
- Alteration of metabolomic profiles by titanium dioxide nanoparticles in human gingivitis model
- (2015) Rene Garcia-Contreras et al. BIOMATERIALS
- Total fluid intake and its determinants: cross-sectional surveys among adults in 13 countries worldwide
- (2015) C. Ferreira-Pêgo et al. EUROPEAN JOURNAL OF NUTRITION
- Interactions between nano-TiO2 and the oral cavity: Impact of nanomaterial surface hydrophilicity/hydrophobicity
- (2015) Birgit J. Teubl et al. JOURNAL OF HAZARDOUS MATERIALS
- A Sensitive Medium-Throughput Method to Predict Intestinal Absorption in Humans Using Rat Intestinal Tissue Segments
- (2015) Laís Cristina Da Silva et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Rapid Kinetics of Size and pH-Dependent Dissolution and Aggregation of Silver Nanoparticles in Simulated Gastric Fluid
- (2015) Jessica L. Axson et al. Journal of Physical Chemistry C
- A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
- (2015) Ilka Maschmeyer et al. LAB ON A CHIP
- Repeated exposure to carbon nanotube-based aerosols does not affect the functional properties of a 3D human epithelial airway model
- (2015) Savvina Chortarea et al. Nanotoxicology
- Translocation of gold nanoparticles across the lung epithelial tissue barrier: Combining in vitro and in silico methods to substitute in vivo experiments
- (2015) Gerald Bachler et al. Particle and Fibre Toxicology
- Nanoparticles skin absorption: New aspects for a safety profile evaluation
- (2015) Francesca Larese Filon et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Mammalian gastrointestinal tract parameters modulating the integrity, surface properties, and absorption of food-relevant nanomaterials
- (2015) Susann Bellmann et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Simulated Biological Fluids with Possible Application in Dissolution Testing
- (2015) Margareth R. C. Marques et al. DISSOLUTION TECHNOLOGIES
- Shape-Dependent Skin Penetration of Silver Nanoparticles: Does It Really Matter?
- (2015) Yu Kyung Tak et al. Scientific Reports
- Nano-hydroxyapatite and Nano-titanium Dioxide Exhibit Different Subcellular Distribution and Apoptotic Profile in Human Oral Epithelium
- (2014) Chor Yong Tay et al. ACS Applied Materials & Interfaces
- Critical Determinants of Uptake and Translocation of Nanoparticles by the Human Pulmonary Alveolar Epithelium
- (2014) Andrew J. Thorley et al. ACS Nano
- The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system
- (2014) Thaher Pelaseyed et al. IMMUNOLOGICAL REVIEWS
- Mucus Layers in Inflammatory Bowel Disease
- (2014) Malin E. V. Johansson INFLAMMATORY BOWEL DISEASES
- Body-on-a-chip simulation with gastrointestinal tract and liver tissues suggests that ingested nanoparticles have the potential to cause liver injury
- (2014) Mandy B. Esch et al. LAB ON A CHIP
- Development of an Advanced Intestinal in Vitro Triple Culture Permeability Model To Study Transport of Nanoparticles
- (2014) Christa Schimpel et al. MOLECULAR PHARMACEUTICS
- Translocation of differently sized and charged polystyrene nanoparticles in in vitro intestinal cell models of increasing complexity
- (2014) Agata P. Walczak et al. Nanotoxicology
- Microfluidic organs-on-chips
- (2014) Sangeeta N Bhatia et al. NATURE BIOTECHNOLOGY
- An in vitro testing strategy towards mimicking the inhalation of high aspect ratio nanoparticles
- (2014) Carola Endes et al. Particle and Fibre Toxicology
- Surface area of the digestive tract – revisited
- (2014) Herbert F Helander et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- In vitrosystems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures
- (2014) Walter K. Schlage et al. TOXICOLOGY MECHANISMS AND METHODS
- The oral cavity as a biological barrier system: Design of an advanced buccal in vitro permeability model
- (2013) Birgit J. Teubl et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation
- (2013) Hyun Jung Kim et al. Integrative Biology
- Development andin vitroevaluation of slippery nanoparticles for enhanced diffusion through native mucus
- (2013) Flavia Laffleur et al. Nanomedicine
- Comparative absorption, distribution, and excretion of titanium dioxide and zinc oxide nanoparticles after repeated oral administration
- (2013) Wan-Seob Cho et al. Particle and Fibre Toxicology
- Titanium dioxide nanoparticles: a review of current toxicological data
- (2013) Hongbo Shi et al. Particle and Fibre Toxicology
- Changes in silver nanoparticles exposed to human synthetic stomach fluid: Effects of particle size and surface chemistry
- (2013) Samuel K. Mwilu et al. SCIENCE OF THE TOTAL ENVIRONMENT
- Development of an Improved Three-Dimensional In Vitro Intestinal Mucosa Model for Drug Absorption Evaluation
- (2013) Na Li et al. TISSUE ENGINEERING PART C-METHODS
- Titanium Dioxide Nanoparticles in Food and Personal Care Products
- (2012) Alex Weir et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Establishment of a triple co-culture in vitro cell models to study intestinal absorption of peptide drugs
- (2012) Filipa Antunes et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles
- (2012) Eleonore Fröhlich International Journal of Nanomedicine
- Industrial production quantities and uses of ten engineered nanomaterials in Europe and the world
- (2012) Fabiano Piccinno et al. JOURNAL OF NANOPARTICLE RESEARCH
- Behaviour of silver nanoparticles and silver ions in anin vitrohuman gastrointestinal digestion model
- (2012) Agata P. Walczak et al. Nanotoxicology
- Oral exposure to polystyrene nanoparticles affects iron absorption
- (2012) Gretchen J. Mahler et al. Nature Nanotechnology
- Ulcerative colitis patients in remission have an altered secretory capacity in the proximal colon despite macroscopically normal mucosa
- (2012) J. K. Gustafsson et al. NEUROGASTROENTEROLOGY AND MOTILITY
- A critical evaluation of in vitro cell culture models for high-throughput drug screening and toxicity
- (2012) Anna Astashkina et al. PHARMACOLOGY & THERAPEUTICS
- Alterations in physical state of silver nanoparticles exposed to synthetic human stomach fluid
- (2012) Kim R. Rogers et al. SCIENCE OF THE TOTAL ENVIRONMENT
- In-Vitro Permeability of Neutral Polystyrene Particles via Buccal Mucosa
- (2012) Birgit Johanna Teubl et al. Small
- Characterization of Translocation of Silver Nanoparticles and Effects on Whole-Genome Gene Expression Using an In Vitro Intestinal Epithelium Coculture Model
- (2011) Hans Bouwmeester et al. ACS Nano
- Oral drug delivery with polymeric nanoparticles: The gastrointestinal mucus barriers
- (2011) Laura M. Ensign et al. ADVANCED DRUG DELIVERY REVIEWS
- Bioavailability and Toxicokinetics of citrate-coated silver nanoparticles in rats
- (2011) Kwangsik Park et al. ARCHIVES OF PHARMACAL RESEARCH
- Ocular surface adverse effects of ambient levels of air pollution
- (2011) André Augusto Miranda Torricelli et al. ARQUIVOS BRASILEIROS DE OFTALMOLOGIA
- Spray-Dried Porcine Plasma Influences Intestinal Barrier Function, Inflammation, and Diarrhea in Weaned Pigs
- (2011) Ralph Michael Peace et al. JOURNAL OF NUTRITION
- Mucus thickness in the gastrointestinal tract of laboratory animals
- (2011) Felipe J. O. Varum et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Aggregation and Dissolution of 4 nm ZnO Nanoparticles in Aqueous Environments: Influence of pH, Ionic Strength, Size, and Adsorption of Humic Acid
- (2011) Shao-Wei Bian et al. LANGMUIR
- Evaluation of a physiologicalin vitrosystem to study the transport of nanoparticles through the buccal mucosa
- (2011) Eva Roblegg et al. Nanotoxicology
- Models for oral uptake of nanoparticles in consumer products
- (2011) Eleonore Fröhlich et al. TOXICOLOGY
- Engineered nanomaterials: exposures, hazards, and risk prevention
- (2011) Robert A Yokel et al. Journal of Occupational Medicine and Toxicology
- Variation in Epidermal Morphology in Human Skin at Different Body Sites as Measured by Reflectance Confocal Microscopy
- (2010) JL Rees et al. ACTA DERMATO-VENEREOLOGICA
- Origin and fate of dietary nanoparticles and microparticles in the gastrointestinal tract
- (2010) Jonathan J. Powell et al. JOURNAL OF AUTOIMMUNITY
- A Three-Dimensional Coculture of Enterocytes, Monocytes and Dendritic Cells To Model Inflamed Intestinal Mucosa in Vitro
- (2010) Fransisca Leonard et al. MOLECULAR PHARMACEUTICS
- Presence and risks of nanosilica in food products
- (2010) Susan Dekkers et al. Nanotoxicology
- Biorelevant Media to Simulate Fluids in the Ascending Colon of Humans and Their Usefulness in Predicting Intracolonic Drug Solubility
- (2010) Maria Vertzoni et al. PHARMACEUTICAL RESEARCH
- Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine
- (2010) M. S. Buzza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toxicity and cellular responses of intestinal cells exposed to titanium dioxide
- (2009) Brian A. Koeneman et al. CELL BIOLOGY AND TOXICOLOGY
- Barrier Capacity of Human Placenta for Nanosized Materials
- (2009) Peter Wick et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Application of biorelevant dissolution tests to the prediction of in vivo performance of diclofenac sodium from an oral modified-release pellet dosage form
- (2009) Ekarat Jantratid et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granuloma
- (2009) Y. Song et al. EUROPEAN RESPIRATORY JOURNAL
- Agglomeration, isolation and dissolution of commercially manufactured silver nanoparticles in aqueous environments
- (2009) Sherrie Elzey et al. JOURNAL OF NANOPARTICLE RESEARCH
- Physiology and Function of the Tight Junction
- (2009) J. M. Anderson et al. Cold Spring Harbor Perspectives in Biology
- Receptor-mediated uptake of ferritin-bound iron by human intestinal Caco-2 cells
- (2008) Swati Kalgaonkar et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Characterization of Caco-2 and HT29-MTX cocultures in an in vitro digestion/cell culture model used to predict iron bioavailability☆
- (2008) Gretchen J. Mahler et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Dissolution Media Simulating Conditions in the Proximal Human Gastrointestinal Tract: An Update
- (2008) Ekarat Jantratid et al. PHARMACEUTICAL RESEARCH
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