Coronavirus disease 2019 (COVID‐19): An overview of the immunopathology, serological diagnosis and management

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

(2020) Dawei Wang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Coronavirus infections and immune responses

(2020) Geng Li et al.   JOURNAL OF MEDICAL VIROLOGY

Development and Clinical Application of A Rapid IgM‐IgG Combined Antibody Test for SARS‐CoV‐2 Infection Diagnosis

(2020) Zhengtu Li et al.   JOURNAL OF MEDICAL VIROLOGY

The outbreak of COVID-19

(2020) Yi-Chi Wu et al.   Journal of the Chinese Medical Association

Baricitinib as potential treatment for 2019-nCoV acute respiratory disease

(2020) Peter Richardson et al.   LANCET

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

(2020) Zhe Xu et al.   Lancet Respiratory Medicine

Use of Mass Cytometry to Profile Human T Cell Exhaustion

(2020) Frances Winkler et al.   Frontiers in Immunology

Diagnosing COVID-19: The Disease and Tools for Detection

(2020) Buddhisha Udugama et al.   ACS Nano

Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan. A Retrospective Observational Study

(2020) Yingzhen Du et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2

(2020) Liang Chen et al.   CARDIOVASCULAR RESEARCH

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

(2020) Francesca Coperchini et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Serology characteristics of SARS-CoV-2 infection since exposure and post symptom onset

(2020) Bin Lou et al.   EUROPEAN RESPIRATORY JOURNAL

Serological and molecular findings during SARS-CoV-2 infection: the first case study in Finland, January to February 2020

(2020) Anu Haveri et al.   Eurosurveillance

Immunology of COVID-19: current state of the science

(2020) Nicolas Vabret et al.   IMMUNITY

Immunopathological characteristics of coronavirus disease 2019 cases in Guangzhou, China

(2020) Mingkai Tan et al.   IMMUNOLOGY

JAK Inhibition as a New Treatment Strategy for Patients with COVID-19

(2020) Farhad Seif et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Eosinophil responses during COVID-19 infections and coronavirus vaccination

(2020) Andrew W. Lindsley et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Laboratory Diagnosis of COVID-19: Current Issues and Challenges

(2020) Yi-Wei Tang et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia

(2020) Fan Wang et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical features and treatment of COVID-19 patients in northeast Chongqing

(2020) Suxin Wan et al.   JOURNAL OF MEDICAL VIROLOGY

ISTH interim guidance on recognition and management of coagulopathy in COVID‐19

(2020) Jecko Thachil et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Kawasaki-like disease: emerging complication during the COVID-19 pandemic

(2020) Russell M Viner et al.   LANCET

An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study

(2020) Lucio Verdoni et al.   LANCET

Human neutralizing antibodies elicited by SARS-CoV-2 infection

(2020) Bin Ju et al.   NATURE

A serological assay to detect SARS-CoV-2 seroconversion in humans

(2020) Fatima Amanat et al.   NATURE MEDICINE

Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19

(2020) Irani Thevarajan et al.   NATURE MEDICINE

Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19

(2020) Yan Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effectiveness of convalescent plasma therapy in severe COVID-19 patients

(2020) Kai Duan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease

(2020) Wenhao Dai et al.   SCIENCE

Report from the American Society for Microbiology COVID-19 International Summit, 23 March 2020: Value of Diagnostic Testing for SARS–CoV-2/COVID-19

(2020) Robin Patel et al.   mBio

Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)

(2020) Bo Diao et al.   Frontiers in Immunology

Coronavirus Disease 2019 in Children — United States, February 12–April 2, 2020

(2020) et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Antibody Tests in Detecting SARS-CoV-2 Infection: A Meta-Analysis

(2020) Panagiota I. Kontou et al.   Diagnostics

In Vitro Diagnostic Assays for COVID-19: Recent Advances and Emerging Trends

(2020) Sandeep Kumar Vashist   Diagnostics

The Role of Cytokines including Interleukin-6 in COVID-19 induced Pneumonia and Macrophage Activation Syndrome-Like Disease

(2020) Dennis McGonagle et al.   AUTOIMMUNITY REVIEWS

COVID-19: Immunology and treatment options

(2020) Susanna Felsenstein et al.   CLINICAL IMMUNOLOGY

Towards treatment planning of COVID-19: Rationale and hypothesis for the use of multiple immunosuppressive agents: Anti-antibodies, immunoglobulins, and corticosteroids

(2020) Amene Saghazadeh et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The pathogenesis and treatment of the `Cytokine Storm' in COVID-19

(2020) Qing Ye et al.   JOURNAL OF INFECTION

Innate immunity in COVID-19 patients mediated by NKG2A receptors, and potential treatment using Monalizumab, Cholroquine, and antiviral agents

(2020) Ahmed Yaqinuddin et al.   MEDICAL HYPOTHESES

Longitudinal analyses reveal immunological misfiring in severe COVID-19

(2020) Carolina Lucas et al.   NATURE

A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2–spike protein–protein interaction

(2020) Chee Wah Tan et al.   NATURE BIOTECHNOLOGY

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

(2020) Jérôme Hadjadj et al.   SCIENCE

Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm

(2020) Chuang Guo et al.   Nature Communications

Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2

(2020) Rui Xiong et al.   Protein & Cell

IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes

(2019) Rudragouda Channappanavar et al.   JOURNAL OF CLINICAL INVESTIGATION

Resolving the fibrotic niche of human liver cirrhosis at single-cell level

(2019) P. Ramachandran et al.   NATURE

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

(2018) Maria L. Agostini et al.   mBio

Dissecting Kawasaki disease: a state-of-the-art review

(2017) S. M. Dietz et al.   EUROPEAN JOURNAL OF PEDIATRICS

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

(2017) Timothy P. Sheahan et al.   Science Translational Medicine

Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

(2016) Rudragouda Channappanavar et al.   Cell Host & Microbe

Middle East respiratory syndrome coronavirus shows poor replication but significant induction of antiviral responses in human monocyte-derived macrophages and dendritic cells

(2016) Janne Tynell et al.   JOURNAL OF GENERAL VIROLOGY

Clinical Progression and Cytokine Profiles of Middle East Respiratory Syndrome Coronavirus Infection

(2016) Eu Suk Kim et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

An Overview of Severe Acute Respiratory Syndrome–Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy

(2016) Thanigaimalai Pillaiyar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Critical role of phospholipase A2group IID in age-related susceptibility to severe acute respiratory syndrome–CoV infection

(2015) Rahul Vijay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

High Secretion of Interferons by Human Plasmacytoid Dendritic Cells upon Recognition of Middle East Respiratory Syndrome Coronavirus

(2015) Vivian A. Scheuplein et al.   JOURNAL OF VIROLOGY

Macrophage activation syndrome in Kawasaki Disease: More common than we thought?

(2015) Wei Wang et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Mechanical Ventilation–associated Lung Fibrosis in Acute Respiratory Distress Syndrome

(2014) Nuria E. Cabrera-Benitez et al.   ANESTHESIOLOGY

Cellular Inhibitor of Apoptosis Protein cIAP2 Protects against Pulmonary Tissue Necrosis during Influenza Virus Infection to Promote Host Survival

(2014) Ian Gaël Rodrigue-Gervais et al.   Cell Host & Microbe

Severe Acute Respiratory Syndrome and Venous Thromboembolism in Multiple Organs

(2013) Yi Xiang-hua et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Macrophage-expressed IFN-β Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia

(2013) Katrin Högner et al.   PLoS Pathogens

Recognition of a Kawasaki Disease Shock Syndrome

(2009) J. T. Kanegaye et al.   PEDIATRICS

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Metabolic Modulation of Inflammation-Induced Activation of Coagulation

(2008) Marcel Levi et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS