Therapeutic Potential of Antidiabetic Medications in the Treatment of Cognitive Dysfunction and Dementia
出版年份 2016 全文链接
标题
Therapeutic Potential of Antidiabetic Medications in the Treatment of Cognitive Dysfunction and Dementia
作者
关键词
Dementia, Metformin, Mild Cognitive Impairment, Rosiglitazone, Pioglitazone
出版物
DRUGS & AGING
Volume 33, Issue 6, Pages 399-409
出版商
Springer Nature
发表日期
2016-04-30
DOI
10.1007/s40266-016-0375-0
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Leptin Reduces Pathology and Improves Memory in a Transgenic Mouse Model of Alzheimer's Disease
- (2017) Steven J. Greco et al. JOURNAL OF ALZHEIMERS DISEASE
- Glimepiride protects neurons against amyloid-β-induced synapse damage
- (2016) Craig Osborne et al. NEUROPHARMACOLOGY
- Insulin resistance predicts brain amyloid deposition in late middle-aged adults
- (2015) Auriel A. Willette et al. Alzheimers & Dementia
- Effect of pioglitazone medication on the incidence of dementia
- (2015) Michael T. Heneka et al. ANNALS OF NEUROLOGY
- The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study
- (2015) Renée FAG de Bruijn et al. BMC Medicine
- Long-term acarbose administration alleviating the impairment of spatial learning and memory in the SAMP8 mice was associated with alleviated reduction of insulin system and acetylated H4K8
- (2015) Wen-Wen Yan et al. BRAIN RESEARCH
- Leptin in Alzheimer's disease
- (2015) Magalhães CA et al. CLINICA CHIMICA ACTA
- Mechanisms of Neurodegeration in Type 2 Diabetes and the Neuroprotective Potential of Dipeptidyl Peptidase 4 Inhibitors
- (2015) E. Matteucci et al. CURRENT MEDICINAL CHEMISTRY
- Risk of Dementia in Seniors With Newly Diagnosed Diabetes: A Population-Based Study
- (2015) Nisha Nigil Haroon et al. DIABETES CARE
- The peroxisome proliferators activated receptor-gamma agonists as therapeutics for the treatment of Alzheimer's disease and mild-to-moderate Alzheimer's disease: a meta-analysis
- (2015) Huawei Cheng et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Early intervention with glucagon-like peptide 1 analog liraglutide prevents tau hyperphosphorylation in diabetic db/db mice
- (2015) De-Lin Ma et al. JOURNAL OF NEUROCHEMISTRY
- Insulin improves memory and reduces chronic neuroinflammation in the hippocampus of young but not aged brains
- (2015) Linda Adzovic et al. Journal of Neuroinflammation
- Severe Hypoglycemia Is Associated With Antidiabetic Oral Treatment Compared With Insulin Analogs in Nursing Home Patients With Type 2 Diabetes and Dementia: Results From the DIMORA Study
- (2015) Angela Marie Abbatecola et al. Journal of the American Medical Directors Association
- Intranasal Insulin Improves Age-Related Cognitive Deficits and Reverses Electrophysiological Correlates of Brain Aging
- (2015) Shaniya Maimaiti et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial
- (2015) Tiia Ngandu et al. LANCET
- Brain GLP-1 and insulin sensitivity
- (2015) Darleen Sandoval et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Impaired insulin action in the human brain: causes and metabolic consequences
- (2015) Martin Heni et al. Nature Reviews Endocrinology
- Hippocampal insulin resistance and cognitive dysfunction
- (2015) Geert Jan Biessels et al. NATURE REVIEWS NEUROSCIENCE
- Type 2 diabetes mellitus and biomarkers of neurodegeneration
- (2015) Chris Moran et al. NEUROLOGY
- Association of Insulin Resistance With Cerebral Glucose Uptake in Late Middle–Aged Adults at Risk for Alzheimer Disease
- (2015) Auriel A. Willette et al. JAMA Neurology
- Glucose regulation, cognition, and brain MRI in type 2 diabetes: a systematic review
- (2015) Stefan L C Geijselaers et al. Lancet Diabetes & Endocrinology
- Low Plasma Leptin in Cognitively Impaired ADNI Subjects: Gender Differences and Diagnostic and Therapeutic Potential
- (2014) Jane Johnston et al. Current Alzheimer Research
- Metabolic effects of SGLT-2 inhibitors beyond increased glucosuria: A review of the clinical evidence
- (2014) A.J. Scheen et al. DIABETES & METABOLISM
- Diabetes and dementia in older people: a Best Clinical Practice Statement by a multidisciplinary National Expert Working Group
- (2014) A. J. Sinclair et al. DIABETIC MEDICINE
- Peroxisome Proliferator-Activated Receptor-Gamma Agonists for Alzheimer’s Disease and Amnestic Mild Cognitive Impairment: A Systematic Review and Meta-Analysis
- (2014) Jia Liu et al. DRUGS & AGING
- Insulin and insulin-like growth factor receptors in the brain: Physiological and pathological aspects
- (2014) Haim Werner et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Dipeptidyl Peptidase-4 Inhibitors Have Protective Effect on Cognitive Impairment in Aged Diabetic Patients With Mild Cognitive Impairment
- (2014) M. R. Rizzo et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Type 2 Diabetes and Antidiabetic Medications in Relation to Dementia Diagnosis
- (2014) Chin Cheng et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Dietary and lifestyle guidelines for the prevention of Alzheimer's disease
- (2014) Neal D. Barnard et al. NEUROBIOLOGY OF AGING
- High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice
- (2014) Steven E. Arnold et al. NEUROBIOLOGY OF DISEASE
- Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide
- (2014) Krzysztof Łabuzek et al. Pharmacological Reports
- Diabetes Mellitus and the Risk of Alzheimer’s Disease: A Nationwide Population-Based Study
- (2014) Chin-Chou Huang et al. PLoS One
- Type 2 diabetes as a risk factor for cognitive impairment: current insights
- (2014) Hiroyuki Umegaki Clinical Interventions in Aging
- Amylin deposition in the brain: A second amyloid in Alzheimer disease?
- (2013) Kaleena Jackson et al. ANNALS OF NEUROLOGY
- TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys
- (2013) Mychael V. Lourenco et al. Cell Metabolism
- Severe Hypoglycemia and Cognitive Decline in Older People With Type 2 Diabetes: The Edinburgh Type 2 Diabetes Study
- (2013) I. Feinkohl et al. DIABETES CARE
- Enhancement of Vasoreactivity and Cognition by Intranasal Insulin in Type 2 Diabetes
- (2013) Vera Novak et al. DIABETES CARE
- Molecular mechanism of action of metformin: old or new insights?
- (2013) Graham Rena et al. DIABETOLOGIA
- Exenatide and the treatment of patients with Parkinson’s disease
- (2013) Iciar Aviles-Olmos et al. JOURNAL OF CLINICAL INVESTIGATION
- Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases
- (2013) Christian Hölscher JOURNAL OF ENDOCRINOLOGY
- Vildagliptin: an anti-diabetes agent ameliorates cognitive deficits and pathology observed in streptozotocin-induced Alzheimer's disease
- (2013) Jayasankar Kosaraju et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Neuroprotective effects of the amylin analogue pramlintide on Alzheimer's disease pathogenesis and cognition
- (2013) Brittany L. Adler et al. NEUROBIOLOGY OF AGING
- Glucose Levels and Risk of Dementia
- (2013) Paul K. Crane et al. NEW ENGLAND JOURNAL OF MEDICINE
- Diabetes mellitus and risk of dementia: A meta-analysis of prospective observational studies
- (2013) Kapil Gudala et al. Journal of Diabetes Investigation
- Association Between Hypoglycemia and Dementia in a Biracial Cohort of Older Adults With Diabetes Mellitus
- (2013) Kristine Yaffe JAMA Internal Medicine
- Midlife type 2 diabetes and poor glycaemic control as risk factors for cognitive decline in early old age: a post-hoc analysis of the Whitehall II cohort study
- (2013) Richard H Tuligenga et al. Lancet Diabetes & Endocrinology
- Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis
- (2012) Kerry Hunter et al. BMC NEUROSCIENCE
- Insulin Has Multiple Antiamyloidogenic Effects on Human Neuronal Cells
- (2012) Giuseppe Pandini et al. ENDOCRINOLOGY
- Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
- (2012) Konrad Talbot et al. JOURNAL OF CLINICAL INVESTIGATION
- Metformin, Other Antidiabetic Drugs, and Risk of Alzheimer's Disease: A Population-Based Case-Control Study
- (2012) Patrick Imfeld et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Impairment
- (2011) Suzanne Craft ARCHIVES OF NEUROLOGY
- Effect of Intranasal Insulin on Cognitive Function: A Systematic Review
- (2011) Elad Shemesh et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Improved diabetes control in the elderly delays global cognitive decline
- (2011) José A. Luchsinger et al. Journal of Nutrition Health & Aging
- Intensive multifactorial treatment and cognitive functioning in screen-detected type 2 diabetes — The ADDITION-Netherlands study: A cluster-randomized trial
- (2011) Paula S. Koekkoek et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): a randomised open-label substudy
- (2011) Lenore J Launer et al. LANCET NEUROLOGY
- A Randomized Pilot Clinical Trial of the Safety of Pioglitazone in Treatment of Patients With Alzheimer Disease
- (2010) David S. Geldmacher et al. ARCHIVES OF NEUROLOGY
- Insulin Resistance and Alzheimer-like Reductions in Regional Cerebral Glucose Metabolism for Cognitively Normal Adults With Prediabetes or Early Type 2 Diabetes
- (2010) Laura D. Baker et al. ARCHIVES OF NEUROLOGY
- A Meta-Analysis of Cytokines in Alzheimer's Disease
- (2010) Walter Swardfager et al. BIOLOGICAL PSYCHIATRY
- Rosiglitazone Monotherapy in Mild-to-Moderate Alzheimer’s Disease: Results from a Randomized, Double-Blind, Placebo-Controlled Phase III Study
- (2010) Michael Gold et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Relationships Between Daily Acute Glucose Fluctuations and Cognitive Performance Among Aged Type 2 Diabetic Patients
- (2010) M. R. Rizzo et al. DIABETES CARE
- Rosiglitazone and Cognitive Stability in Older Individuals With Type 2 Diabetes and Mild Cognitive Impairment
- (2010) A. M. Abbatecola et al. DIABETES CARE
- Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: potential involvement of AKT and mitochondria biogenesis
- (2010) R. Fan et al. DIABETES OBESITY & METABOLISM
- Insulin metabolism and the risk of Alzheimer disease: The Rotterdam Study
- (2010) E. M. C. Schrijvers et al. NEUROLOGY
- Insulin resistance is associated with the pathology of Alzheimer disease: The Hisayama Study
- (2010) T. Matsuzaki et al. NEUROLOGY
- Diabetes increases brain damage caused by severe hypoglycemia
- (2009) Adam J. Bree et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Cognitive function and risks of cardiovascular disease and hypoglycaemia in patients with type 2 diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial
- (2009) B. E. de Galan et al. DIABETOLOGIA
- Long-term inhibition of dipeptidyl peptidase-4 in Alzheimer’s prone mice
- (2009) Michele D’Amico et al. EXPERIMENTAL GERONTOLOGY
- Hypoglycemic Episodes and Risk of Dementia in Older Patients With Type 2 Diabetes Mellitus
- (2009) Rachel A. Whitmer JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Exendin-4 protects dopaminergic neurons by inhibition of microglial activation and matrix metalloproteinase-3 expression in an animal model of Parkinson's disease
- (2009) Sehee Kim et al. JOURNAL OF ENDOCRINOLOGY
- PIOGLITAZONE IMPROVED COGNITION IN A PILOT STUDY ON PATIENTS WITH ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT WITH DIABETES MELLITUS
- (2009) Haruo Hanyu et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Effects of insulinic therapy on cognitive impairment in patients with Alzheimer disease and Diabetes Mellitus type-2
- (2009) Massimiliano Plastino et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease
- (2009) Tomohiko Sato et al. NEUROBIOLOGY OF AGING
- Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system
- (2009) Alison Hamilton et al. NEUROREPORT
- Dipeptydil peptidase-4 inhibitors in type 2 diabetes: A meta-analysis of randomized clinical trials
- (2009) M. Monami et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription
- (2009) Y. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid
- (2008) Victor A. Gault et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Insulin in combination with other diabetes medication is associated with less Alzheimer neuropathology
- (2008) M. S. Beeri et al. NEUROLOGY
- Amyloid beta oligomers induce impairment of neuronal insulin receptors
- (2007) Wei-Qin Zhao et al. FASEB JOURNAL
- Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of parkinson's disease
- (2007) Göran Bertilsson et al. JOURNAL OF NEUROSCIENCE RESEARCH
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