SARS-CoV-2, ACE2 expression, and systemic organ invasion

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa

(2020) Hao Xu et al.   International Journal of Oral Science

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

(2020) Zhe Xu et al.   Lancet Respiratory Medicine

COVID-19, ACE2, and the cardiovascular consequences

(2020) Andrew M. South et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

(2020) Vanessa Monteil et al.   CELL

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

(2020) Shuai Xia et al.   CELL RESEARCH

The pivotal link between ACE2 deficiency and SARS-CoV-2 infection

(2020) Paolo Verdecchia et al.   European Journal of Internal Medicine

Objective evaluation of anosmia and ageusia in COVID ‐19 patients: Single‐center experience on 72 cases

(2020) Luigi Angelo Vaira et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Chilblain‐like lesions on feet and hands during the COVID‐19 Pandemic

(2020) Nerea Landa et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Neutralization of SARS-CoV-2 spike pseudotyped virus by recombinant ACE2-Ig

(2020) Changhai Lei et al.   Nature Communications

TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes

(2020) Ruochen Zang et al.   Science Immunology

Acute kidney injury in critically ill patients with COVID-19

(2020) Paul Gabarre et al.   INTENSIVE CARE MEDICINE

Blockade of SARS-CoV-2 infection by recombinant soluble ACE2

(2020) Francois Alhenc-Gelas et al.   KIDNEY INTERNATIONAL

Oral saliva and COVID-19

(2020) Maryam Baghizadeh Fini   ORAL ONCOLOGY

Expression of Renin-Angiotensin System Components in the Taste Organ of Mice

(2019) Noriatsu Shigemura et al.   Nutrients

Plasma levels of the proprotein convertase furin and incidence of diabetes and mortality

(2018) C. Fernandez et al.   JOURNAL OF INTERNAL MEDICINE

ISSUE INFORMATION

(2017)   Hemodialysis International

Meta-analysis of gut microbiome studies identifies disease-specific and shared responses

(2017) Claire Duvallet et al.   Nature Communications

Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after Infection

(2017) Qi Wu et al.   Scientific Reports

Role of the ACE2/Angiotensin 1–7 Axis of the Renin–Angiotensin System in Heart Failure

(2016) Vaibhav B. Patel et al.   CIRCULATION RESEARCH

Acute respiratory distress syndrome

(2016) Rob Mac Sweeney et al.   LANCET

Angiotensin-(1-5), an active mediator of renin-angiotensin system, stimulates ANP secretion via Mas receptor

(2016) Lamei Yu et al.   PEPTIDES

ACE inhibition, ACE2 and angiotensin-(1⿿7) axis in kidney and cardiac inflammation and fibrosis

(2016) Ana Cristina Simões e Silva et al.   PHARMACOLOGICAL RESEARCH

Genetic Deletion of ACE2 Induces Vascular Dysfunction in C57BL/6 Mice: Role of Nitric Oxide Imbalance and Oxidative Stress

(2016) Luiza A. Rabelo et al.   PLoS One

ACE2 deficiency reduces β-cell mass and impairs β-cell proliferation in obese C57BL/6 mice

(2015) Robin Shoemaker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

ACE2 and Ang-(1–7) protect endothelial cell function and prevent early atherosclerosis by inhibiting inflammatory response

(2015) Yue-Hui Zhang et al.   INFLAMMATION RESEARCH

Brain Angiotensin-Converting Enzyme Type 2 Shedding Contributes to the Development of Neurogenic Hypertension

(2013) Huijing Xia et al.   CIRCULATION RESEARCH

Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction

(2010) JiuChang Zhong et al.   CIRCULATION

ACE2 and Diabetes: ACE of ACEs?

(2010) D. Batlle et al.   DIABETES

Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes

(2009) Jin-Kui Yang et al.   ACTA DIABETOLOGICA

Lipid rafts are involved in SARS-CoV entry into Vero E6 cells

(2008) Yanning Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Angiotensin-converting enzyme 2 in the brain: properties and future directions

(2008) Huijing Xia et al.   JOURNAL OF NEUROCHEMISTRY

Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2

(2008) J. Netland et al.   JOURNAL OF VIROLOGY