Genetic Deletion of ACE2 Induces Vascular Dysfunction in C57BL/6 Mice: Role of Nitric Oxide Imbalance and Oxidative Stress

Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes

(2015) Yang Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Angiotensin-Converting Enzyme 2 Is a Critical Determinant of Angiotensin II–Induced Loss of Vascular Smooth Muscle Cells and Adverse Vascular Remodeling

(2014) Vaibhav B. Patel et al.   HYPERTENSION

Prevention of chronic disease in the 21st century: elimination of the leading preventable causes of premature death and disability in the USA

(2014) Ursula E Bauer et al.   LANCET

Angiotensin-Converting Enzyme 2 Activation Improves Endothelial Function

(2013) Rodrigo A. Fraga-Silva et al.   HYPERTENSION

ACE2 deficiency induced perivascular fibrosis and cardiac hypertrophy during postnatal development in mice

(2013) Tomozo Moritani et al.   Journal of the American Society of Hypertension

Uncoupling Protein-2 Protects Endothelial Function in Diet-Induced Obese Mice

(2012) Xiao Yu Tian et al.   CIRCULATION RESEARCH

Enhanced Angiotensin II-Induced Cardiac and Aortic Remodeling in ACE2 Knockout Mice

(2012) Mahmoud S. Alghamri et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

ACE2 Deficiency Enhances Angiotensin II-Mediated Aortic Profilin-1 Expression, Inflammation and Peroxynitrite Production

(2012) Hai-Yan Jin et al.   PLoS One

Impact of ACE2 Deficiency and Oxidative Stress on Cerebrovascular Function With Aging

(2012) Ricardo A. Peña Silva et al.   STROKE

Association of ACE2 Genetic Variants With Blood Pressure, Left Ventricular Mass, and Cardiac Function in Caucasians With Type 2 Diabetes

(2011) S. K. Patel et al.   AMERICAN JOURNAL OF HYPERTENSION

Angiotensin-Converting Enzyme 2 Deficiency in Whole Body or Bone Marrow–Derived Cells Increases Atherosclerosis in Low-Density Lipoprotein Receptor −/− Mice

(2011) Sean E. Thatcher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47phox NADPH oxidase subunit

(2011) Sreedhar Bodiga et al.   CARDIOVASCULAR RESEARCH

A Pilot Assessment of Oxidative Stress Byproducts and Antioxidant Activities Among Indian Patients with Various Stages of Hypertension

(2011) Raman Saraswathi et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

eNOS activation and NO function: Structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity

(2011) Ruslan Rafikov et al.   JOURNAL OF ENDOCRINOLOGY

Genetic Ace2 Deficiency Accentuates Vascular Inflammation and Atherosclerosis in the ApoE Knockout Mouse

(2010) Merlin C. Thomas et al.   CIRCULATION RESEARCH

Loss of ACE2 accelerates time-dependent glomerular and tubulointerstitial damage in streptozotocin-induced diabetic mice

(2010) Atsushi Shiota et al.   HYPERTENSION RESEARCH

ACE2–angiotensin-(1–7)–Mas axis and oxidative stress in cardiovascular disease

(2010) Luiza A Rabelo et al.   HYPERTENSION RESEARCH

Reactive oxygen species and vascular biology: implications in human hypertension

(2010) Rhian M Touyz et al.   HYPERTENSION RESEARCH

SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS

(2009) G. Y. Oudit et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Atorvastatin Prevents Angiotensin II–Induced Vascular Remodeling and Oxidative Stress

(2009) Ana M. Briones et al.   HYPERTENSION

Reactive oxygen-derived free radicals are key to the endothelial dysfunction of diabetes

(2009) Yi SHI et al.   Journal of Diabetes

Angiotensin-converting enzyme 2 gene targeting studies in mice: mixed messages

(2008) Susan B. Gurley et al.   EXPERIMENTAL PHYSIOLOGY

Transgenic Angiotensin-Converting Enzyme 2 Overexpression in Vessels of SHRSP Rats Reduces Blood Pressure and Improves Endothelial Function

(2008) Brit Rentzsch et al.   HYPERTENSION

Endothelial Dysfunction and Elevated Blood Pressure in Mas Gene-Deleted Mice

(2008) Ping Xu et al.   HYPERTENSION

Phosphorylation of Endothelial Nitric-oxide Synthase Regulates Superoxide Generation from the Enzyme

(2008) Chun-An Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ablation of angiotensin (1-7) receptor Mas in C57Bl/6 mice causes endothelial dysfunction

(2008) Luiza A. Rabelo et al.   Journal of the American Society of Hypertension

Oxygen-derived free radicals mediate endothelium-dependent contractions in femoral arteries of rats with streptozotocin-induced diabetes

(2007) Y Shi et al.   BRITISH JOURNAL OF PHARMACOLOGY