Total Glucosides of Peony Protect Cardiomyocytes against Oxidative Stress and Inflammation by Reversing Mitochondrial Dynamics and Bioenergetics

Pum2-Mff axis fine-tunes mitochondrial quality control in acute ischemic kidney injury

(2020) Jin Wang et al.   CELL BIOLOGY AND TOXICOLOGY

Pathological Roles of Mitochondrial Oxidative Stress and Mitochondrial Dynamics in Cardiac Microvascular Ischemia/Reperfusion Injury

(2020) Hao Zhou et al.   Biomolecules

Role of mitochondrial quality control in the pathogenesis of nonalcoholic fatty liver disease

(2020) Ruibing Li et al.   Aging-US

New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury

(2020) Jin Wang et al.   ANGIOGENESIS

UVA Induced Oxidative Stress Was Inhibited by Paeoniflorin/Nrf2 Signaling or PLIN2

(2020) Yan-Song Lu et al.   Frontiers in Pharmacology

Total glucosides of paeony: A review of its phytochemistry, role in autoimmune diseases, and mechanisms of action

(2020) Huajuan Jiang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Mitochondrial quality control in cardiac microvascular ischemia-reperfusion injury: New insights into the mechanisms and therapeutic potentials

(2020) Jin Wang et al.   PHARMACOLOGICAL RESEARCH

Total glucosides of paeony (TGP) alleviates constipation and intestinal inflammation in mice induced by Sjögren's syndrome

(2020) Ge Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Nuphar alkaloids induce very rapid apoptosis through a novel caspase-dependent but BAX/BAK-independent pathway

(2019) David J. Mallick et al.   CELL BIOLOGY AND TOXICOLOGY

Calpains mediate isoproterenol-induced hypertrophy through modulation of GRK2

(2019) David Aluja et al.   BASIC RESEARCH IN CARDIOLOGY

Inflammation and fibrosis in murine models of heart failure

(2019) Lucas Bacmeister et al.   BASIC RESEARCH IN CARDIOLOGY

Protein kinase/phosphatase balance mediates the effects of increased late sodium current on ventricular calcium cycling

(2019) Jörg Eiringhaus et al.   BASIC RESEARCH IN CARDIOLOGY

Blocking the IL-1β signalling pathway prevents chronic viral myocarditis and cardiac remodeling

(2019) Lisa Kraft et al.   BASIC RESEARCH IN CARDIOLOGY

Protection against cardiac ischemia-reperfusion injury by hypothermia and by inhibition of succinate accumulation and oxidation is additive

(2019) M. Kohlhauer et al.   BASIC RESEARCH IN CARDIOLOGY

E2f1 deletion attenuates infarct-induced ventricular remodeling without affecting O-GlcNAcylation

(2019) Sujith Dassanayaka et al.   BASIC RESEARCH IN CARDIOLOGY

Functional wiring of proteostatic and mitostatic modules ensures transient organismal survival during imbalanced mitochondrial dynamics

(2019) Sentiljana Gumeni et al.   Redox Biology

Revascularization after angiogenesis inhibition favors new sprouting over abandoned vessel reuse

(2019) Anthony Mukwaya et al.   ANGIOGENESIS

Mitochondrial fission protein 1 up-regulation ameliorates senescence-related endothelial dysfunction of human endothelial progenitor cells

(2019) Hsueh-Hsiao Wang et al.   ANGIOGENESIS

Total Glucosides of Paeony protects against collagen-induced mouse arthritis via inhibiting follicular helper T cell differentiation

(2019) Hui Li et al.   PHYTOMEDICINE

Therapeutic contribution of melatonin to the treatment of septic cardiomyopathy: A novel mechanism linking Ripk3-modified mitochondrial performance and endoplasmic reticulum function

(2019) Jiankai Zhong et al.   Redox Biology

PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation

(2019) Qisheng Lin et al.   Redox Biology

Therapies to limit myocardial injury in animal models of myocarditis: a systematic review and meta-analysis

(2019) Joshua A. Silverblatt et al.   BASIC RESEARCH IN CARDIOLOGY

Acute exposure to nocturnal train noise induces endothelial dysfunction and pro-thromboinflammatory changes of the plasma proteome in healthy subjects

(2019) Johannes Herzog et al.   BASIC RESEARCH IN CARDIOLOGY

Antithrombotic Effects of Paeoniflorin from Paeonia suffruticosa by Selective Inhibition on Shear Stress-Induced Platelet Aggregation

(2019) Thien Ngo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A review for the anti-inflammatory effects of paeoniflorin in inflammatory disorders

(2019) Qiqi Xin et al.   LIFE SCIENCES

The melanogenic effects and underlying mechanism of paeoniflorin in human melanocytes and vitiligo mice

(2019) Murong Hu et al.   FITOTERAPIA

Complementary & Alternative Medicine for Alopecia Areata: A Systematic Review

(2019) Elizabeth Tkachenko et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony

(2019) Lingling Zhang et al.   PHARMACOLOGY & THERAPEUTICS

Role of linc00174/miR-138-5p (miR-150-5p)/FOSL2 Feedback Loop on Regulating the Blood-Tumor Barrier Permeability

(2019) Jizhe Guo et al.   Molecular Therapy-Nucleic Acids

Molecular imaging of cardiac remodelling after myocardial infarction

(2018) Daniel Curley et al.   BASIC RESEARCH IN CARDIOLOGY

Protective effects of a traditional Chinese herbal formula Jiang-Xian HuGan on Concanavalin A-induced mouse hepatitis via NF-κB and Nrf2 signaling pathways

(2018) Huan-Huan Tang et al.   JOURNAL OF ETHNOPHARMACOLOGY

6′-O-Galloylpaeoniflorin Attenuates Cerebral Ischemia Reperfusion-Induced Neuroinflammation and Oxidative Stress via PI3K/Akt/Nrf2 Activation

(2018) Zhongmei Wen et al.   Oxidative Medicine and Cellular Longevity

Effects of paeoniflorin on neurobehavior, oxidative stress, brain insulin signaling, and synaptic alterations in intracerebroventricular streptozotocin-induced cognitive impairment in mice

(2018) Dongmei Wang et al.   PHYSIOLOGY & BEHAVIOR

Empagliflozin rescues diabetic myocardial microvascular injury via AMPK-mediated inhibition of mitochondrial fission

(2018) Hao Zhou et al.   Redox Biology

Excess vascular endothelial growth factor-A disrupts pericyte recruitment during blood vessel formation

(2018) Jordan Darden et al.   ANGIOGENESIS

Paeoniflorin attenuates atRAL-induced oxidative stress, mitochondrial dysfunction and endoplasmic reticulum stress in retinal pigment epithelial cells via triggering Ca2+/CaMKII-dependent activation of AMPK

(2018) Xue Zhu et al.   ARCHIVES OF PHARMACAL RESEARCH

Redox regulation by reversible protein S-thiolation in Gram-positive bacteria

(2018) Marcel Imber et al.   Redox Biology

AVE 0991 attenuates oxidative stress and neuronal apoptosis via Mas/PKA/CREB/UCP-2 pathway after subarachnoid hemorrhage in rats

(2018) Jun Mo et al.   Redox Biology

The regulatory network of miR-141 in the inhibition of angiogenesis

(2018) Haojie Dong et al.   ANGIOGENESIS

Extracellular vesicles of multiple myeloma cells utilize the proteasome inhibitor mechanism to moderate endothelial angiogenesis

(2018) Moran Zarfati et al.   ANGIOGENESIS

ADAM10 controls the differentiation of the coronary arterial endothelium

(2018) Gregory Farber et al.   ANGIOGENESIS

Staphylococcus aureus alpha toxin activates Notch in vascular cells

(2018) Sonia L. Hernandez et al.   ANGIOGENESIS

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection—evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology

(2018) Sean M. Davidson et al.   BASIC RESEARCH IN CARDIOLOGY

Programmed Necrosis and Disease:We interrupt your regular programming to bring you necroinflammation

(2018) Eui Ho Kim et al.   CELL DEATH AND DIFFERENTIATION

Death and fire—the concept of necroinflammation

(2018) Andreas Linkermann   CELL DEATH AND DIFFERENTIATION

Role of AMPK pathway in lead-induced endoplasmic reticulum stress in kidney and in paeonol-induced protection in mice

(2018) Chan-Min Liu et al.   FOOD AND CHEMICAL TOXICOLOGY

Formulated Chinese Medicine Shaoyao Gancao Tang Reduces Tau Aggregation and Exerts Neuroprotection through Anti-Oxidation and Anti-Inflammation

(2018) I-Cheng Chen et al.   Oxidative Medicine and Cellular Longevity

Redox regulation of cell state and fate

(2018) Bernice Woon Li Lee et al.   Redox Biology

Glucose-dependent trans-plasma membrane electron transport and p70S6k phosphorylation in skeletal muscle cells

(2018) Shannon C. Kelly et al.   Redox Biology

Calcium signals between the ryanodine receptor- and mitochondria critically regulate the effects of arsenite on mitochondrial superoxide formation and on the ensuing survival vs apoptotic signaling

(2018) Andrea Guidarelli et al.   Redox Biology

A maladaptive ER stress response triggers dysfunction in highly active muscles of mice with SELENON loss

(2018) Diego Pozzer et al.   Redox Biology

A novel role for NUPR1 in the keratinocyte stress response to UV oxidized phospholipids

(2018) Marie-Sophie Narzt et al.   Redox Biology

Therapeutic potential of the mitochondria-targeted antioxidant MitoQ in mitochondrial-ROS induced sensorineural hearing loss caused by Idh2 deficiency

(2018) Ye-Ri Kim et al.   Redox Biology

Mst1 deletion attenuates renal ischaemia-reperfusion injury: The role of microtubule cytoskeleton dynamics, mitochondrial fission and the GSK3β-p53 signalling pathway

(2018) Hongyan Li et al.   Redox Biology

Strategies to detect mitochondrial oxidants

(2018) Alicia J. Kowaltowski   Redox Biology

Endogenous cholesterol ester hydroperoxides modulate cholesterol levels and inhibit cholesterol uptake in hepatocytes and macrophages

(2018) Shuyuan Guo et al.   Redox Biology

The impact of xanthine oxidase (XO) on hemolytic diseases

(2018) Heidi M. Schmidt et al.   Redox Biology

Nephroprotective effect of Paeonia emodi via inhibition of advanced glycation end products and oxidative stress in streptozotocin–nicotinamide induced diabetic nephropathy

(2017) Lalit Kishore et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Mff‐Dependent Mitochondrial Fission Contributes to the Pathogenesis of Cardiac Microvasculature Ischemia/Reperfusion Injury via Induction of mROS‐Mediated Cardiolipin Oxidation and HK2/VDAC1 Disassociation‐Involved mPTP Opening

(2017) Hao Zhou et al.   Journal of the American Heart Association

Prevention of Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice by Paeonol

(2017) Meng-Han Liu et al.   Frontiers in Physiology

Ripk3 induces mitochondrial apoptosis via inhibition of FUNDC1 mitophagy in cardiac IR injury

(2017) Hao Zhou et al.   Redox Biology

Paeoniflorin protects Schwann cells against high glucose induced oxidative injury by activating Nrf2/ARE pathway and inhibiting apoptosis

(2016) Xinwei Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

The herbal extract KCHO-1 exerts a neuroprotective effect by ameliorating oxidative stress via heme oxygenase-1 upregulation

(2016) DONG-SUNG LEE et al.   Molecular Medicine Reports

Paeoniflorin inhibition of 6-hydroxydopamine-induced apoptosis in PC12 cells via suppressing reactive oxygen species-mediated PKCδ/NF-κB pathway

(2015) H. Dong et al.   NEUROSCIENCE

Protection of H9c2 rat cardiomyoblasts against oxidative insults by total paeony glucosides from Radix Paeoniae Rubrae

(2013) Cheng Luo et al.   PHYTOMEDICINE