Neuroblast senescence in the aged brain augments natural killer cell cytotoxicity leading to impaired neurogenesis and cognition

The Emergence of Natural Killer Cells as a Major Target in Cancer Immunotherapy

(2019) Fernando Souza-Fonseca-Guimaraes et al.   TRENDS IN IMMUNOLOGY

Immunoneuropsychiatry — novel perspectives on brain disorders

(2019) Katrin Pape et al.   Nature Reviews Neurology

Single-cell analysis reveals T cell infiltration in old neurogenic niches

(2019) Ben W. Dulken et al.   NATURE

Cellular Senescence: Defining a Path Forward

(2019) Vassilis Gorgoulis et al.   CELL

Physiological changes in neurodegeneration — mechanistic insights and clinical utility

(2018) Rebekah M. Ahmed et al.   Nature Reviews Neurology

Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty

(2018) Luigi Ferrucci et al.   Nature Reviews Cardiology

Inflammaging: a new immune–metabolic viewpoint for age-related diseases

(2018) Claudio Franceschi et al.   Nature Reviews Endocrinology

Cutting Edge: Local Proliferation of Uterine Tissue-Resident NK Cells during Decidualization in Mice

(2018) Dorothy K. Sojka et al.   JOURNAL OF IMMUNOLOGY

NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination

(2018) Marcus Ruscetti et al.   SCIENCE

Brain Ischemia Suppresses Immunity in the Periphery and Brain via Different Neurogenic Innervations

(2017) Qiang Liu et al.   IMMUNITY

Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states

(2017) David Furman et al.   NATURE MEDICINE

cGAS drives noncanonical-inflammasome activation in age-related macular degeneration

(2017) Nagaraj Kerur et al.   NATURE MEDICINE

Senescent cells: an emerging target for diseases of ageing

(2017) Bennett G. Childs et al.   NATURE REVIEWS DRUG DISCOVERY

Aging-Associated TNF Production Primes Inflammasome Activation and NLRP3-Related Metabolic Disturbances

(2016) Franz Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Age-Associated Resident Memory CD8 T Cells in the Central Nervous System Are Primed To Potentiate Inflammation after Ischemic Brain Injury

(2016) Rodney M. Ritzel et al.   JOURNAL OF IMMUNOLOGY

Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation

(2016) Qiang Liu et al.   NATURE NEUROSCIENCE

Prospective separation and transcriptome analyses of cortical projection neurons and interneurons based on lineage tracing by Tbr2 (Eomes)-GFP/Dcx-mRFP reporters

(2015) Jiancheng Liu et al.   Developmental Neurobiology

Characterization of a unique cell population marked by transgene expression in the adult cochlea of nestin-CreERT2/tdTomato-reporter mice

(2015) Cynthia L. Chow et al.   JOURNAL OF COMPARATIVE NEUROLOGY

NK-DC crosstalk controls the autopathogenic Th17 response through an innate IFN-γ–IL-27 axis

(2015) Wai Po Chong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

(2015) Nicolás Herranz et al.   NATURE CELL BIOLOGY

Cellular senescence in aging and age-related disease: from mechanisms to therapy

(2015) Bennett G Childs et al.   NATURE MEDICINE

Brain health and shared risk factors for dementia and stroke

(2015) Hannah Gardener et al.   Nature Reviews Neurology

DNA Damage, DNA Repair, Aging, and Neurodegeneration

(2015) Scott Maynard et al.   Cold Spring Harbor Perspectives in Medicine

Fgd5identifies hematopoietic stem cells in the murine bone marrow

(2014) Roi Gazit et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ischemic neurons recruit natural killer cells that accelerate brain infarction

(2014) Y. Gan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition

(2013) Eric O. Long et al.   Annual Review of Immunology

Dynamics of the meningeal CD4+ T-cell repertoire are defined by the cervical lymph nodes and facilitate cognitive task performance in mice

(2013) A Radjavi et al.   MOLECULAR PSYCHIATRY

Physiology: Inflammation links ageing to the brain

(2013) Dana Gabuzda et al.   NATURE

Fate-Restricted Neural Progenitors in the Mammalian Cerebral Cortex

(2012) S. J. Franco et al.   SCIENCE

MHCI negatively regulates synapse density during the establishment of cortical connections

(2011) Marian W Glynn et al.   NATURE NEUROSCIENCE

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Interleukin-27 Activates Natural Killer Cells and Suppresses NK-Resistant Head and Neck Squamous Cell Carcinoma through Inducing Antibody-Dependent Cellular Cytotoxicity

(2009) M. Matsui et al.   CANCER RESEARCH

CCL3 and CXCL12 regulate trafficking of mouse bone marrow NK cell subsets

(2008) G. Bernardini et al.   BLOOD

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

IL-27-Mediated Activation of Natural Killer Cells and Inflammation Produced Antitumour Effects for Human Oesophageal Carcinoma Cells

(2008) L. Liu et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY