The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens

Transbilayer Movement of Sphingomyelin Precedes Catastrophic Breakage of Enterobacteria-Containing Vacuoles

(2020) Cara J. Ellison et al.   CURRENT BIOLOGY

Cross-presentation of exogenous antigens on MHC I molecules

(2020) Jeff D Colbert et al.   CURRENT OPINION IN IMMUNOLOGY

Small Molecule Enhancers of Endosome-to-Cytosol Import Augment Anti-tumor Immunity

(2020) Patrycja Kozik et al.   Cell Reports

Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells

(2019) Dali Han et al.   NATURE

Thioesterase PPT1 balances viral resistance and efficient T cell crosspriming in dendritic cells

(2019) Pengju Ou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Myosin II Synergizes with F-Actin to Promote DNGR-1-Dependent Cross-Presentation of Dead Cell-Associated Antigens

(2018) Oliver Schulz et al.   Cell Reports

WDFY4 is required for cross-presentation in response to viral and tumor antigens

(2018) Derek J. Theisen et al.   SCIENCE

VAMP8-mediated NOX2 recruitment to endosomes is necessary for antigen release

(2017) Ilse Dingjan et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Critical role for Sec22b-dependent antigen cross-presentation in antitumor immunity

(2017) Andrés Alloatti et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export

(2017) Jeff E. Grotzke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A pH‐ and ionic strength‐dependent conformational change in the neck region regulates DNGR‐1 function in dendritic cells

(2016) Pavel Hanč et al.   EMBO JOURNAL

Optimal Generation of Tissue-Resident but Not Circulating Memory T Cells during Viral Infection Requires Crosspriming by DNGR-1 + Dendritic Cells

(2016) Salvador Iborra et al.   IMMUNITY

RAB43 facilitates cross-presentation of cell-associated antigens by CD8α + dendritic cells

(2016) Nicole M. Kretzer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microscopy Image Browser: A Platform for Segmentation and Analysis of Multidimensional Datasets

(2016) Ilya Belevich et al.   PLOS BIOLOGY

Lipid peroxidation causes endosomal antigen release for cross-presentation

(2016) Ilse Dingjan et al.   Scientific Reports

Toll-like Receptor 4 Engagement on Dendritic Cells Restrains Phago-Lysosome Fusion and Promotes Cross-Presentation of Antigens

(2015) Andrés Alloatti et al.   IMMUNITY

Oncogenic Transformation of Dendritic Cells and Their Precursors Leads to Rapid Cancer Development in Mice

(2015) Jan P. Böttcher et al.   JOURNAL OF IMMUNOLOGY

Are ERAD components involved in cross-presentation?

(2015) Jeff E. Grotzke et al.   MOLECULAR IMMUNOLOGY

TLR Signals Induce Phagosomal MHC-I Delivery from the Endosomal Recycling Compartment to Allow Cross-Presentation

(2014) Priyanka Nair-Gupta et al.   CELL

Genetic Tracing via DNGR-1 Expression History Defines Dendritic Cells as a Hematopoietic Lineage

(2013) Barbara U. Schraml et al.   CELL

The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

(2012) Jian-Guo Zhang et al.   IMMUNITY

The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice

(2012) Santiago Zelenay et al.   JOURNAL OF CLINICAL INVESTIGATION

The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice

(2012) Salvador Iborra et al.   JOURNAL OF CLINICAL INVESTIGATION

Conventional Dendritic Cells Require IRAP-Rab14 Endosomes for Efficient Cross-Presentation

(2012) M. Weimershaus et al.   JOURNAL OF IMMUNOLOGY

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

TrakEM2 Software for Neural Circuit Reconstruction

(2012) Albert Cardona et al.   PLoS One

Influenza A Virus Infection of Human Primary Dendritic Cells Impairs Their Ability to Cross-Present Antigen to CD8 T Cells

(2012) Anna Smed-Sörensen et al.   PLoS Pathogens

Novel Murine Dendritic Cell Lines: A Powerful Auxiliary Tool for Dendritic Cell Research

(2012) Silvia A. Fuertes Marraco et al.   Frontiers in Immunology

Sec22b Regulates Phagosomal Maturation and Antigen Crosspresentation by Dendritic Cells

(2011) Ignacio Cebrian et al.   CELL

Mannose receptor polyubiquitination regulates endosomal recruitment of p97 and cytosolic antigen translocation for cross-presentation

(2011) M. Zehner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancing Serial Block-Face Scanning Electron Microscopy to Enable High Resolution 3-D Nanohistology of Cells and Tissues

(2010) TJ Deerinck et al.   MICROSCOPY AND MICROANALYSIS

Oncogenic Braf Induces Melanocyte Senescence and Melanoma in Mice

(2009) Nathalie Dhomen et al.   CANCER CELL

The Small GTPase Rac2 Controls Phagosomal Alkalinization and Antigen Crosspresentation Selectively in CD8+ Dendritic Cells

(2009) Ariel Savina et al.   IMMUNITY

Lysosomes as “Suicide Bags” in Cell Death: Myth or Reality?

(2009) Boris Turk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

(2009) David Sancho et al.   NATURE

Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation

(2009) R. Belizaire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset

(2008) M. L. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE