The pathways related to glutamine metabolism, glutamine inhibitors and their implication for improving the efficiency of chemotherapy in triple-negative breast cancer
出版年份 2021 全文链接
标题
The pathways related to glutamine metabolism, glutamine inhibitors and their implication for improving the efficiency of chemotherapy in triple-negative breast cancer
作者
关键词
Glutamine metabolism, Warburg effect, Ferroptosis, TCA cycle, Apoptosis, Glutaminase inhibitors, Triple-negative breast cancer
出版物
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
Volume 787, Issue -, Pages 108366
出版商
Elsevier BV
发表日期
2021-01-19
DOI
10.1016/j.mrrev.2021.108366
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Molecular subtypes of triple-negative breast cancer in women of different race and ethnicity
- (2019) Yuan Chun Ding et al. Oncotarget
- Targeting Glutamine Metabolism for Cancer Treatment
- (2018) Yeon-Kyung Choi et al. Biomolecules & Therapeutics
- Combined drug therapeutic strategies for the effective treatment of Triple Negative Breast Cancer
- (2018) Naveen K.R. Chalakur-Ramireddy et al. BIOSCIENCE REPORTS
- First international TNBC conference meeting report
- (2018) Padmashree Rida et al. BREAST CANCER RESEARCH AND TREATMENT
- To eat or not to eat — the metabolic flavor of ferroptosis
- (2018) Minghui Gao et al. CURRENT OPINION IN CELL BIOLOGY
- Promising New Agents for Colorectal Cancer
- (2018) Satya Das et al. CURRENT TREATMENT OPTIONS IN ONCOLOGY
- How the Warburg effect supports aggressiveness and drug resistance of cancer cells?
- (2018) Philippe Icard et al. DRUG RESISTANCE UPDATES
- Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism
- (2018) Qingqiu Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- l-Glutamine Attenuates Apoptosis in Porcine Enterocytes by Regulating Glutathione-Related Redox Homeostasis
- (2018) Ning Liu et al. JOURNAL OF NUTRITION
- Glutamine metabolism regulates FLIP expression and sensitivity to TRAIL in triple-negative breast cancer cells
- (2018) Marta Mauro-Lizcano et al. Cell Death & Disease
- Molecular link between glucose and glutamine consumption in cancer cells mediated by CtBP and SIRT4
- (2018) Li Wang et al. Oncogenesis
- Glutaminase isoenzymes in the metabolic therapy of cancer
- (2018) José M. Matés et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Bioassay-guided isolation of cantharidin from blister beetles and its anticancer activity through inhibition of epidermal growth factor receptor-mediated STAT3 and Akt pathways
- (2018) Jaemoo Chun et al. Journal of Natural Medicines
- Glutaminase inhibitors: a patent review
- (2018) CanRong Wu et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Altered glutamine metabolism in breast cancer; subtype dependencies and alternative adaptations
- (2017) Rokaya El Ansari et al. HISTOPATHOLOGY
- Cystine uptake through the cystine/glutamate antiporter xCT triggers glioblastoma cell death under glucose deprivation
- (2017) Takeo Goji et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metabolite Profiling Reveals the Glutathione Biosynthetic Pathway as a Therapeutic Target in Triple-Negative Breast Cancer
- (2017) Alexander Beatty et al. MOLECULAR CANCER THERAPEUTICS
- Metabolic Interactions in the Tumor Microenvironment
- (2017) Costas A. Lyssiotis et al. TRENDS IN CELL BIOLOGY
- CHAC1 degradation of glutathione enhances cystine-starvation-induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2-eIF2α-ATF4 pathway
- (2017) Meng-Shian Chen et al. Oncotarget
- The emerging role and targetability of the TCA cycle in cancer metabolism
- (2017) Nicole M. Anderson et al. Protein & Cell
- Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition
- (2017) Michael Lampa et al. PLoS One
- Design and evaluation of novel glutaminase inhibitors
- (2016) Lee A. McDermott et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Ferroptosis: process and function
- (2016) Y Xie et al. CELL DEATH AND DIFFERENTIATION
- Mechanisms of ferroptosis
- (2016) Jennifer Yinuo Cao et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
- (2016) Kenichi Shimada et al. Nature Chemical Biology
- Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease
- (2016) Giampaolo Bianchini et al. Nature Reviews Clinical Oncology
- Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence
- (2016) Justin M. Balko et al. Science Translational Medicine
- The Warburg Effect: How Does it Benefit Cancer Cells?
- (2016) Maria V. Liberti et al. TRENDS IN BIOCHEMICAL SCIENCES
- Ferroptosis: Death by Lipid Peroxidation
- (2016) Wan Seok Yang et al. TRENDS IN CELL BIOLOGY
- Turn up the cellular power generator with vitamin E analogue formulation
- (2016) Ru Wen et al. Chemical Science
- Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells
- (2016) Bradley Smith et al. Cell Reports
- Lactate dehydrogenase 5: An old friend and a new hope in the war on cancer
- (2015) Katarzyna Augoff et al. CANCER LETTERS
- Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population
- (2015) Neil E. Bhola et al. CANCER RESEARCH
- Lactate promotes glutamine uptake and metabolism in oxidative cancer cells
- (2015) Jhudit Pérez-Escuredo et al. CELL CYCLE
- JAK inhibitors and myelofibrosis, Einstein and ruxolitinib
- (2015) C. Harrison HAEMATOLOGICA
- Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach
- (2015) Lian Chen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Metabolic reprogramming: the emerging concept and associated therapeutic strategies
- (2015) Go J. Yoshida JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K
- (2015) Rupert Courtnay et al. MOLECULAR BIOLOGY REPORTS
- Glutaminolysis and Transferrin Regulate Ferroptosis
- (2015) Minghui Gao et al. MOLECULAR CELL
- Metabolic pathways promoting cancer cell survival and growth
- (2015) Lindsey K. Boroughs et al. NATURE CELL BIOLOGY
- Glutaminolysis as a target for cancer therapy
- (2015) L Jin et al. ONCOGENE
- JAK inhibitors and myelofibrosis, Einstein and ruxolitinib
- (2015) C. Harrison HAEMATOLOGICA
- Fenofibrate induces apoptosis of triple-negative breast cancer cells via activation of NF-κB pathway
- (2014) Ting Li et al. BMC CANCER
- Subtyping of triple-negative breast cancer: Implications for therapy
- (2014) Vandana G. Abramson et al. CANCER
- Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer
- (2014) M. I. Gross et al. MOLECULAR CANCER THERAPEUTICS
- Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport
- (2014) Chendong Yang et al. MOLECULAR CELL
- Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment
- (2014) Daniel Ackerman et al. TRENDS IN CELL BIOLOGY
- The prognostic impact of age in patients with triple-negative breast cancer
- (2013) Cornelia Liedtke et al. BREAST CANCER RESEARCH AND TREATMENT
- Glutamine and cancer: cell biology, physiology, and clinical opportunities
- (2013) Christopher T. Hensley et al. JOURNAL OF CLINICAL INVESTIGATION
- HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
- (2013) Gregg L. Semenza JOURNAL OF CLINICAL INVESTIGATION
- Wnt signaling blockage inhibits cell proliferation and migration, and induces apoptosis in triple-negative breast cancer cells
- (2013) Birdal Bilir et al. Journal of Translational Medicine
- Metabolic targets for cancer therapy
- (2013) Lorenzo Galluzzi et al. NATURE REVIEWS DRUG DISCOVERY
- Co-targeting of the PI3K pathway improves the response of BRCA1 deficient breast cancer cells to PARP1 inhibition
- (2012) Siker Kimbung et al. CANCER LETTERS
- Efficacy of everolimus, a novel mTOR inhibitor, against basal-like triple-negative breast cancer cells
- (2012) Mayu Yunokawa et al. CANCER SCIENCE
- Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers
- (2012) Xin-Sheng Deng et al. CELL CYCLE
- Genistein inhibits MDA-MB-231 triple-negative breast cancer cell growth by inhibiting NF-κB activity via the Notch-1 pathway
- (2012) HONG PAN et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Dissecting the Heterogeneity of Triple-Negative Breast Cancer
- (2012) Otto Metzger-Filho et al. JOURNAL OF CLINICAL ONCOLOGY
- Targeting EGFR in Triple Negative Breast Cancer
- (2012) Naoto T. Ueno et al. Journal of Cancer
- Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells
- (2011) Desheng Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Wnt/β-Catenin Pathway Activation Is Enriched in Basal-Like Breast Cancers and Predicts Poor Outcome
- (2010) Andrey I. Khramtsov et al. AMERICAN JOURNAL OF PATHOLOGY
- The Warburg and Crabtree effects: On the origin of cancer cell energy metabolism and of yeast glucose repression
- (2010) Rodrigo Diaz-Ruiz et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Resiliency and Vulnerability in the HER2-HER3 Tumorigenic Driver
- (2010) D. N. Amin et al. Science Translational Medicine
- Glutamine addiction: a new therapeutic target in cancer
- (2010) David R. Wise et al. TRENDS IN BIOCHEMICAL SCIENCES
- Changes related to phosphatidylinositol 3-kinase/Akt signaling in leiomyomas: possible involvement of glycogen synthase kinase 3α and cyclin D2 in the pathophysiology
- (2009) Laila Karra et al. FERTILITY AND STERILITY
- Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
- (2009) R J DeBerardinis et al. ONCOGENE
- Pyruvate into lactate and back: From the Warburg effect to symbiotic energy fuel exchange in cancer cells
- (2009) Olivier Feron RADIOTHERAPY AND ONCOLOGY
- The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
- (2008) Ralph J. DeBerardinis et al. Cell Metabolism
- Plumbagin-induced apoptosis of human breast cancer cells is mediated by inactivation of NF-κB and Bcl-2
- (2008) Aamir Ahmad et al. JOURNAL OF CELLULAR BIOCHEMISTRY
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