标题
Role of the GH-IGF1 system in progression of cancer
作者
关键词
Growth hormone (GH), Insulin-like growth factor-1 (IGF1), IGF1 receptor, Laron syndrome, Mechanisms of cancer protection
出版物
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Volume 518, Issue -, Pages 111003
出版商
Elsevier BV
发表日期
2020-09-10
DOI
10.1016/j.mce.2020.111003
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Insulin-like growth factor-1, insulin-like growth factor-binding protein-3, and breast cancer risk: observational and Mendelian randomization analyses with ∼430 000 women
- (2020) N. Murphy et al. ANNALS OF ONCOLOGY
- Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients
- (2020) Tali Sinai-Livne et al. Oncotarget
- Investigational IGF1R inhibitors in early stage clinical trials for cancer therapy
- (2019) Haim Werner et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Type 1 IGF receptor associates with adverse outcome and cellular radioresistance in paediatric high-grade glioma
- (2019) Aaron D. Simpson et al. BRITISH JOURNAL OF CANCER
- From dwarves to giants: South American's contribution to the history of growth hormone and related disorders
- (2019) Cesar Luiz Boguszewski et al. GROWTH HORMONE & IGF RESEARCH
- Characterization of an Activating R1353H Insulin-like Growth Factor 1 Receptor Variant in a Male with Extreme Tall Height
- (2018) Yingbo Lin et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- MECHANISMS IN ENDOCRINOLOGY: Lessons from growth hormone receptor gene-disrupted mice: are there benefits of endocrine defects?
- (2018) Reetobrata Basu et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Differential expression of IGFBPs in Laron syndrome-derived lymphoblastoid cell lines: Potential correlation with reduced cancer incidence
- (2018) Lina Somri et al. GROWTH HORMONE & IGF RESEARCH
- Oncogenic fusion proteins adopt the insulin-like growth factor signaling pathway
- (2018) Haim Werner et al. Molecular Cancer
- Identification of thioredoxin-interacting protein (TXNIP) as a downstream target for IGF1 action
- (2018) Karthik Nagaraj et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Increased risk of bone tumors after growth hormone treatment in childhood: A population-based cohort study in France
- (2018) Amélie Poidvin et al. Cancer Medicine
- The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects
- (2018) Farhad Dehkhoda et al. Frontiers in Endocrinology
- Systemic complications of acromegaly and the impact of the current treatment landscape: an update
- (2018) Mônica R Gadelha et al. ENDOCRINE REVIEWS
- A Consensus Statement on acromegaly therapeutic outcomes
- (2018) Shlomo Melmed et al. Nature Reviews Endocrinology
- Growth Hormone's Links to Cancer
- (2018) Cesar Luiz Boguszewski et al. ENDOCRINE REVIEWS
- MECHANISMS IN ENDOCRINOLOGY: The multiple facets of GHRH/GH/IGF-I axis: lessons from lifetime, untreated, isolated GH deficiency due to a GHRH receptor gene mutation
- (2017) Manuel H Aguiar-Oliveira et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- IGF-I deficiency, longevity and cancer protection of patients with Laron syndrome
- (2017) Zvi Laron et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Growth Hormone Receptor Knockdown Sensitizes Human Melanoma Cells to Chemotherapy by Attenuating Expression of ABC Drug Efflux Pumps
- (2017) Reetobrata Basu et al. Hormones & Cancer
- Identification of BRCA1 As a Potential Biomarker for Insulin-Like Growth Factor-1 Receptor Targeted Therapy in Breast Cancer
- (2017) Tali Cohen-Sinai et al. Frontiers in Endocrinology
- Phase I Dose-Escalation Study of Linsitinib (OSI-906) and Erlotinib in Patients with Advanced Solid Tumors
- (2016) V. M. Macaulay et al. CLINICAL CANCER RESEARCH
- Identification of signaling pathways associated with cancer protection in Laron syndrome
- (2016) Lena Lapkina-Gendler et al. ENDOCRINE-RELATED CANCER
- MANAGEMENT OF ENDOCRINE DISEASE: Acromegaly and cancer: an old debate revisited
- (2016) Cesar Luiz Boguszewski et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Complications of acromegaly: thyroid and colon
- (2016) Amit Tirosh et al. Pituitary
- Insulin-like Growth Factor 1 Signaling Axis Meets p53 Genome Protection Pathways
- (2016) Haim Werner et al. Frontiers in Oncology
- Mortality in acromegaly: a 20-year follow-up study
- (2015) Elina Ritvonen et al. ENDOCRINE-RELATED CANCER
- Growth hormone and cancer: GH production and action in glioma?
- (2015) Robert W. Lea et al. GENERAL AND COMPARATIVE ENDOCRINOLOGY
- Reviewing the safety of GH replacement therapy in adults
- (2015) Kirstine Stochholm et al. GROWTH HORMONE & IGF RESEARCH
- Risk of Neoplasia in Pediatric Patients Receiving Growth Hormone Therapy—A Report From the Pediatric Endocrine Society Drug and Therapeutics Committee
- (2015) Sripriya Raman et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Minireview: Were the IGF Signaling Inhibitors All Bad?
- (2015) Heather Beckwith et al. MOLECULAR ENDOCRINOLOGY
- Transcriptional and epigenetic control of IGF1R gene expression: Implications in metabolism and cancer
- (2014) Haim Werner et al. GROWTH HORMONE & IGF RESEARCH
- Growth Hormone Exposure as a Risk Factor for the Development of Subsequent Neoplasms of the Central Nervous System: A Report From the Childhood Cancer Survivor Study
- (2014) Briana C. Patterson et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Growth hormone protects colorectal cancer cells from radiation by improving the ability of DNA damage repair
- (2014) XIAO-YU WU et al. Molecular Medicine Reports
- The IGF Hormonal Network in Endometrial Cancer: Functions, Regulation, and Targeting Approaches
- (2014) Ilan Bruchim et al. Frontiers in Endocrinology
- Human metastatic melanoma cell lines express high levels of growth hormone receptor and respond to GH treatment
- (2013) Elahu G. Sustarsic et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity
- (2013) A Molchadsky et al. CELL DEATH AND DIFFERENTIATION
- Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulation
- (2013) Leonard Girnita et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Growth hormone is a cellular senescence target in pituitary and nonpituitary cells
- (2013) V. Chesnokova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autocrine human GH promotes radioresistance in mammary and endometrial carcinoma cells
- (2012) Nicola M Bougen et al. ENDOCRINE-RELATED CANCER
- BRCA1 is Expressed in Uterine Serous Carcinoma (USC) and Controls Insulin-Like Growth Factor I Receptor (IGF-IR) Gene Expression in USC Cell Lines
- (2012) Keren Amichay et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- The decline and fall of the IGF-I receptor
- (2012) Renato Baserga JOURNAL OF CELLULAR PHYSIOLOGY
- Reports of Increased Mortality and GH: Will This Affect Current Clinical Practice?
- (2012) Saul Malozowski JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Long-Term Mortality after Recombinant Growth Hormone Treatment for Isolated Growth Hormone Deficiency or Childhood Short Stature: Preliminary Report of the French SAGhE Study
- (2012) Jean-Claude Carel et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- IGF-1 and BRCA1 signalling pathways in familial cancer
- (2012) Haim Werner et al. LANCET ONCOLOGY
- A Phase I Pharmacokinetic and Pharmacodynamic Study of Dalotuzumab (MK-0646), an Anti-Insulin-like Growth Factor-1 Receptor Monoclonal Antibody, in Patients with Advanced Solid Tumors
- (2011) F. Atzori et al. CLINICAL CANCER RESEARCH
- p53 Regulates insulin-like growth factor-I receptor gene expression in uterine serous carcinoma and predicts responsiveness to an insulin-like growth factor-I receptor-directed targeted therapy
- (2011) Zohar Attias-Geva et al. EUROPEAN JOURNAL OF CANCER
- Congenital IGF1 deficiency tends to confer protection against post-natal development of malignancies
- (2011) Rachel Steuerman et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Tumor suppressors govern insulin-like growth factor signaling pathways: implications in metabolism and cancer
- (2011) H Werner ONCOGENE
- Growth Hormone Receptor Deficiency Is Associated with a Major Reduction in Pro-Aging Signaling, Cancer, and Diabetes in Humans
- (2011) J. Guevara-Aguirre et al. Science Translational Medicine
- The insulin-like growth factor-I receptor inhibitor figitumumab (CP-751,871) in combination with docetaxel in patients with advanced solid tumours: results of a phase Ib dose-escalation, open-label study
- (2010) L R Molife et al. BRITISH JOURNAL OF CANCER
- New plays in the p53 theater
- (2010) Yael Aylon et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Targeting insulin-like growth factor 1 receptor in sarcomas
- (2010) Katia Scotlandi et al. CURRENT OPINION IN ONCOLOGY
- Differential regulation of insulin-like growth factor-I receptor gene expression by wild type and mutant androgen receptor in prostate cancer cells
- (2010) Hagit Schayek et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Long-Term Safety of Recombinant Human Growth Hormone in Children
- (2009) J. Bell et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- AMG 479, a fully human anti-insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells
- (2009) P. J. Beltran et al. MOLECULAR CANCER THERAPEUTICS
- Paracrine Overexpression of Insulin-Like Growth Factor-1 Enhances Mammary Tumorigenesis in Vivo
- (2008) Krisztina Kovács de Ostrovich et al. AMERICAN JOURNAL OF PATHOLOGY
- Reduced Susceptibility to Two-Stage Skin Carcinogenesis in Mice with Low Circulating Insulin-Like Growth Factor I Levels
- (2008) T. Moore et al. CANCER RESEARCH
- The Type 1 Insulin-Like Growth Factor Receptor Pathway
- (2008) M. M. Chitnis et al. CLINICAL CANCER RESEARCH
- Autocrine Human Growth Hormone Stimulates Oncogenicity of Endometrial Carcinoma Cells
- (2008) Vijay Pandey et al. ENDOCRINOLOGY
- Autocrine Human Growth Hormone Promotes Tumor Angiogenesis in Mammary Carcinoma
- (2008) Severine E. Brunet-Dunand et al. ENDOCRINOLOGY
- Mortality in Acromegaly: A Metaanalysis
- (2007) O. M. Dekkers et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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