Extracellular cardiolipin modulates microglial phagocytosis and cytokine secretion in a toll-like receptor (TLR) 4-dependent manner

Short-chain fatty acids (SCFAs) alone or in combination regulate select immune functions of microglia-like cells

(2020) Tyler J. Wenzel et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Extracellular cardiolipin regulates select immune functions of microglia and microglia-like cells

(2019) Caitlin B. Pointer et al.   BRAIN RESEARCH BULLETIN

Cytochrome c can be released into extracellular space and modulate functions of human astrocytes in a toll-like receptor 4-dependent manner

(2019) Tyler J. Wenzel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4

(2019) Malvina Pizzuto et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Phagocytosis in the Brain: Homeostasis and Disease

(2019) Dylan A. Galloway et al.   Frontiers in Immunology

Regional microglia are transcriptionally distinct but similarly exacerbate neurodegeneration in a culture model of Parkinson’s disease

(2018) Eric Wildon Kostuk et al.   Journal of Neuroinflammation

Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson’s disease pathogenesis

(2018) Craig D. Hughes et al.   ACTA NEUROPATHOLOGICA

Pyrazole Compound 2-MBAPA as a Novel Inhibitor of Microglial Activation and Neurotoxicity in vitro and in vivo

(2018) Sadayuki Hashioka et al.   JOURNAL OF ALZHEIMERS DISEASE

The effects of insulin on the inflammatory activity of BV2 microglia

(2018) Fiona Brabazon et al.   PLoS One

Damage-Associated Molecular Patterns in Inflammatory Diseases

(2018) Jong Seong Roh et al.   Immune Network

The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia

(2017) Krishnendu Chakraborty et al.   Nature Communications

Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy

(2017) Kevin A. Clayton et al.   Frontiers in Neuroscience

Cardiolipin in Central Nervous System Physiology and Pathology

(2016) Caitlin B. Pointer et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Gx-50 reduces β-amyloid-induced TNF-α, IL-1β, NO, and PGE2expression and inhibits NF-κB signaling in a mouse model of Alzheimer's disease

(2016) Shi Shi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Danger-associated molecular patterns in Alzheimer’s disease

(2016) Carmen Venegas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Molecular mechanisms of innate memory and tolerance to LPS

(2016) John J. Seeley et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Isolation of highly enriched primary human microglia for functional studies

(2016) Justin Rustenhoven et al.   Scientific Reports

Exogenous α-synuclein induces toll-like receptor 4 dependent inflammatory responses in astrocytes

(2015) Emmy H. Rannikko et al.   BMC NEUROSCIENCE

The role of the nitric oxide pathway in brain injury and its treatment — From bench to bedside

(2015) P.S. Garry et al.   EXPERIMENTAL NEUROLOGY

Dichotomous roles for externalized cardiolipin in extracellular signaling: Promotion of phagocytosis and attenuation of innate immunity

(2015) Krishnakumar Balasubramanian et al.   Science Signaling

Dichotomous roles for externalized cardiolipin in extracellular signaling: Promotion of phagocytosis and attenuation of innate immunity

(2015) Krishnakumar Balasubramanian et al.   Science Signaling

Opposing Roles of Interferon-Gamma on Cells of the Central Nervous System in Autoimmune Neuroinflammation

(2015) Payton A. Ottum et al.   Frontiers in Immunology

A Comparative Review of Toll-Like Receptor 4 Expression and Functionality in Different Animal Species

(2014) Céline Vaure et al.   Frontiers in Immunology

Toll-Like Receptor 4 Agonistic Antibody Promotes Innate Immunity against Severe Pneumonia Induced by Coinfection with Influenza Virus and Streptococcus pneumoniae

(2013) Akitaka Tanaka et al.   Clinical and Vaccine Immunology

Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation

(2013) Shankar S. Iyer et al.   IMMUNITY

IL-1β and TNF-α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase

(2013) Ling Ye et al.   JOURNAL OF NEUROCHEMISTRY

Microglia are the major source of TNF-α and TGF-β1 in postnatal glial cultures; regulation by cytokines, lipopolysaccharide, and vitronectin

(2013) Jennifer V. Welser-Alves et al.   NEUROCHEMISTRY INTERNATIONAL

Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation

(2013) Cintia Roodveldt et al.   PLoS One

Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology

(2013) J.-P. Michaud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microfluidic Chemotaxis Platform for Differentiating the Roles of Soluble and Bound Amyloid-β on Microglial Accumulation

(2013) Hansang Cho et al.   Scientific Reports

Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia

(2012) Lisa Fellner et al.   GLIA

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

(2012) K. Schroder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resolution-associated molecular patterns (RAMP): RAMParts defending immunological homeostasis?

(2011) A. M. Shields et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Neuronal MCP-1 Mediates Microglia Recruitment and Neurodegeneration Induced by the Mild Impairment of Oxidative Metabolism

(2010) Guang Yang et al.   BRAIN PATHOLOGY

Host species-specific usage of the TLR4-LPS receptor complex

(2008) Regina Lizundia et al.   Innate Immunity