Cardiolipin in Central Nervous System Physiology and Pathology

Cardiolipin Profile Changes are Associated to the Early Synaptic Mitochondrial Dysfunction in Alzheimer's Disease

(2018) Vera F. Monteiro-Cardoso et al.   JOURNAL OF ALZHEIMERS DISEASE

Reduced cardiolipin content decreases respiratory chain capacities and increases ATP synthesis yield in the human HepaRG cells

(2016) Laure Peyta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The ionization properties of cardiolipin and its variants in model bilayers

(2016) Murugappan Sathappa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cardiolipin-mediated procoagulant activity of mitochondria contributes to traumatic brain injury-associated coagulopathy in mice

(2016) Z. Zhao et al.   BLOOD

Therapies targeting lipid peroxidation in traumatic brain injury

(2016) Tamil Selvan Anthonymuthu et al.   BRAIN RESEARCH

Cardiolipin or MTCH2 can serve as tBID receptors during apoptosis

(2016) E Raemy et al.   CELL DEATH AND DIFFERENTIATION

New targets for monitoring and therapy in Barth syndrome

(2016) W. Reid Thompson et al.   GENETICS IN MEDICINE

Dark microglia: A new phenotype predominantly associated with pathological states

(2016) Kanchan Bisht et al.   GLIA

Defining functional classes of Barth syndrome mutation in humans

(2016) Ya-Wen Lu et al.   HUMAN MOLECULAR GENETICS

Increased Electron Paramagnetic Resonance Signal Correlates with Mitochondrial Dysfunction and Oxidative Stress in an Alzheimer’s disease Mouse Brain

(2016) Du Fang et al.   JOURNAL OF ALZHEIMERS DISEASE

The contribution of alpha synuclein to neuronal survival and function - Implications for Parkinson's disease

(2016) Matthew J. Benskey et al.   JOURNAL OF NEUROCHEMISTRY

Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson’s Disease

(2016) Shaoxiao Wang et al.   PLoS One

The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function

(2016) Samuel E. Marsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction of α-synuclein with biomembranes in Parkinson's disease —role of cardiolipin

(2016) Stephanie Ghio et al.   PROGRESS IN LIPID RESEARCH

Barth Syndrome: From Mitochondrial Dysfunctions Associated with Aberrant Production of Reactive Oxygen Species to Pluripotent Stem Cell Studies

(2016) Ana Saric et al.   Frontiers in Genetics

Metabolomics Reveals New Mechanisms for Pathogenesis in Barth Syndrome and Introduces Novel Roles for Cardiolipin in Cellular Function

(2016) Yana Sandlers et al.   PLoS One

Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagy

(2015) Paul Hsu et al.   Autophagy

Exogenous cardiolipin localizes to mitochondria and prevents TAZ knockdown-induced apoptosis in myeloid progenitor cells

(2015) Nikita Ikon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cardiolipin metabolism and its causal role in the etiology of the inherited cardiomyopathy Barth syndrome

(2015) Gerard J. Gaspard et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Cardiolipin and Its Different Properties in Mitophagy and Apoptosis

(2015) Xiao-Xiao Li et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Tau in physiology and pathology

(2015) Yipeng Wang et al.   NATURE REVIEWS NEUROSCIENCE

Ceramides in Alzheimer’s Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and AβAccumulation

(2015) Maja Jazvinšćak Jembrek et al.   Oxidative Medicine and Cellular Longevity

Disorders of phospholipid metabolism: an emerging class of mitochondrial disease due to defects in nuclear genes

(2015) Ya-Wen Lu et al.   Frontiers in Genetics

Neuroinflammation in Parkinson’s disease and its potential as therapeutic target

(2015) Qinqin Wang et al.   Translational Neurodegeneration

LC3 binds externalized cardiolipin on injured mitochondria to signal mitophagy in neurons

(2014) Charleen T Chu et al.   Autophagy

Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits

(2014) Dun-Sheng Yang et al.   BRAIN

α-Synuclein amino terminus regulates mitochondrial membrane permeability

(2014) Jiamei Shen et al.   BRAIN RESEARCH

α-Synuclein oligomers distinctively permeabilize complex model membranes

(2014) Anja N. D. Stefanovic et al.   FEBS Journal

Cardiolipin-incorporated liposomes with surface CRM197 for enhancing neuronal survival against neurotoxicity

(2014) Yung-Chih Kuo et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Modulation of the Respiratory Supercomplexes in Yeast

(2014) Tie-Zhong Cui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deciphering of Mitochondrial Cardiolipin Oxidative Signaling in Cerebral Ischemia-Reperfusion

(2014) Jing Ji et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Astrocytic modulation of blood brain barrier: perspectives on Parkinson’s disease

(2014) Ricardo Cabezas et al.   Frontiers in Cellular Neuroscience

Mitochondrial membrane permeabilisation by amyloid aggregates and protection by polyphenols

(2013) Angelique Camilleri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mammalian cardiolipin biosynthesis

(2013) Edgard M. Mejia et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Effect of nanoparticles binding ß-amyloid peptide on nitric oxide production by cultured endothelial cells and macrophages

(2013) Francesca Re et al.   International Journal of Nanomedicine

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

(2013) Charleen T. Chu et al.   NATURE CELL BIOLOGY

Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain

(2013) E. Lapuente-Brun et al.   SCIENCE

Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration

(2013) E.-M. Mandelkow et al.   Cold Spring Harbor Perspectives in Medicine

Cardiolipin remodeling and the function of tafazzin

(2012) Michael Schlame   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Seven functional classes of Barth syndrome mutation

(2012) Kevin Whited et al.   HUMAN MOLECULAR GENETICS

Origin of the Conformational Heterogeneity of Cardiolipin-Bound Cytochrome c

(2012) Yuning Hong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury

(2012) Jing Ji et al.   NATURE NEUROSCIENCE

Cardiolipin Affects the Supramolecular Organization of ATP Synthase in Mitochondria

(2011) Devrim Acehan et al.   BIOPHYSICAL JOURNAL

Mitochondrial ATP synthase: architecture, function and pathology

(2011) An I. Jonckheere et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Mitochondrial dysfunction in brain aging: Role of oxidative stress and cardiolipin

(2011) Giuseppe Paradies et al.   NEUROCHEMISTRY INTERNATIONAL

A Mathematical Model for the Determination of Steady-State Cardiolipin Remodeling Mechanisms Using Lipidomic Data

(2011) Lu Zhang et al.   PLoS One

Oxidative Stress in Parkinson's Disease

(2010) Chun Zhou et al.   Annals of the New York Academy of Sciences

Lipid-based nanoparticles with high binding affinity for amyloid-β1–42 peptide

(2010) Marco Gobbi et al.   BIOMATERIALS

Clinical characteristics and pathophysiological mechanisms of focal and diffuse traumatic brain injury

(2010) Teuntje M. J. C. Andriessen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury

(2010) Louis J. Sparvero et al.   JOURNAL OF NEUROCHEMISTRY

Microglial activation and chronic neurodegeneration

(2010) Melinda E. Lull et al.   Neurotherapeutics

In Vitro Growth Environment Produces Lipidomic and Electron Transport Chain Abnormalities in Mitochondria from Non-Tumorigenic Astrocytes and Brain Tumours

(2009) Michael A Kiebish et al.   ASN Neuro

Mitochondrial kinases and their molecular interaction with cardiolipin

(2009) Uwe Schlattner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mitochondrial Creatine Kinase Binding to Phospholipid Monolayers Induces Cardiolipin Segregation

(2009) Ofelia Maniti et al.   BIOPHYSICAL JOURNAL

Role of cardiolipin peroxidation and Ca2+ in mitochondrial dysfunction and disease

(2009) Giuseppe Paradies et al.   CELL CALCIUM

Cytochrome c/cardiolipin relations in mitochondria: a kiss of death

(2009) Valerian E. Kagan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Peroxidase Mechanism of Lipid-dependent Cross-linking of Synuclein with Cytochromec

(2009) Hülya Bayır et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic Ablation of Calcium-independent Phospholipase A2γ Leads to Alterations in Hippocampal Cardiolipin Content and Molecular Species Distribution, Mitochondrial Degeneration, Autophagy, and Cognitive Dysfunction

(2009) David J. Mancuso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shotgun Lipidomics Reveals the Temporally Dependent, Highly Diversified Cardiolipin Profile in the Mammalian Brain: Temporally Coordinated Postnatal Diversification of Cardiolipin Molecular Species with Neuronal Remodeling†

(2008) Hua Cheng et al.   BIOCHEMISTRY

Oxidative stress and mitochondrial dysfunction in neurodegeneration; cardiolipin a critical target?

(2008) Simon Pope et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria

(2008) Michael A. Kiebish et al.   JOURNAL OF NEUROCHEMISTRY

Respiratory Active Mitochondrial Supercomplexes

(2008) Rebeca Acín-Pérez et al.   MOLECULAR CELL

Mitochondrial dysfunction in rat brain with agingInvolvement of complex I, reactive oxygen species and cardiolipin

(2008) G PETROSILLO et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroglia: the 150 years after

(2008) Helmut Kettenmann et al.   TRENDS IN NEUROSCIENCES