Mendelian randomization analysis identified genes pleiotropically associated with the risk and prognosis of COVID-19

Abnormal Coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia

(2020) Ning Tang et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

An interactive web-based dashboard to track COVID-19 in real time

(2020) Ensheng Dong et al.   LANCET INFECTIOUS DISEASES

Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia

(2020) Qun Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

(2020)   Nature Microbiology

Is Low Alveolar Type II Cell SOD3 in the Lungs of Elderly Linked to the Observed Severity of COVID-19?

(2020) Ahmed S. Abouhashem et al.   ANTIOXIDANTS & REDOX SIGNALING

The COVID-19 Pandemic: A Global Natural Experiment

(2020) Blake Thomson   CIRCULATION

The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic

(2020)   EUROPEAN JOURNAL OF HUMAN GENETICS

Interferon-α2b Treatment for COVID-19

(2020) Qiong Zhou et al.   Frontiers in Immunology

Attention should be paid to venous thromboembolism prophylaxis in the management of COVID-19

(2020) Tao Wang et al.   Lancet Haematology

Immunothrombotic Dysregulation in COVID-19 Pneumonia is Associated with Respiratory Failure and Coagulopathy

(2020) Leo Nicolai et al.   CIRCULATION

Interplay between SARS-CoV-2 and the type I interferon response

(2020) Margarida Sa Ribero et al.   PLoS Pathogens

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

(2019) Eleonora Porcu et al.   Nature Communications

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

NK cell–intrinsic FcεRIγ limits CD8+ T-cell expansion and thereby turns an acute into a chronic viral infection

(2019) Vikas Duhan et al.   PLoS Pathogens

Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease

(2019) Tianxiao Huan et al.   Nature Communications

Type III interferons: Balancing tissue tolerance and resistance to pathogen invasion

(2019) Achille Broggi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Paraoxonase-2 regulates coagulation activation through endothelial tissue factor

(2018) Julia Ebert et al.   BLOOD

ATF4 Deficiency Promotes Intestinal Inflammation in Mice by Reducing Uptake of Glutamine and Expression of Antimicrobial Peptides

(2018) Xiaoming Hu et al.   GASTROENTEROLOGY

Mendelian Randomization

(2017) Connor A. Emdin et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

Rapid and Efficient Stable Gene Transfer to Mesenchymal Stromal Cells Using a Modified Foamy Virus Vector

(2016) Nathan Paul Sweeney et al.   MOLECULAR THERAPY

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

(2016) Zhihong Zhu et al.   NATURE GENETICS

Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits

(2016) Jennifer M. Whitehead Pavlides et al.   Genome Medicine

Human IFNAR2 deficiency: Lessons for antiviral immunity

(2015) Christopher J. A. Duncan et al.   Science Translational Medicine

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

Beyond GWASs: Illuminating the Dark Road from Association to Function

(2013) Stacey L. Edwards et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Activating transcription factor 4 is involved in endoplasmic reticulum stress-mediated apoptosis contributing to vascular calcification

(2013) Xiao-Hui Duan et al.   APOPTOSIS

Leptin and leptin-related gene polymorphisms, obesity, and influenza A/H1N1 vaccine-induced immune responses in older individuals

(2013) Inna G. Ovsyannikova et al.   VACCINE

Modulation of paraoxonases during infectious diseases and its potential impact on atherosclerosis

(2012) Ayman Farid et al.   Lipids in Health and Disease

TRIM5 Acts as More Than a Retroviral Restriction Factor

(2011) Suresh De Silva et al.   Viruses-Basel

One Enzyme, Two Functions

(2010) Sebastian Altenhöfer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Role for the Human Nucleotide-binding Domain, Leucine-rich Repeat-containing Family Member NLRC5 in Antiviral Responses

(2010) Andreas Neerincx et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MCM3AP, a novel HBV integration site in hepatocellular carcinoma and its implication in hepatocarcinogenesis

(2010) Jing Wang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences