SOD3 deficiency induces liver fibrosis by promoting hepatic stellate cell activation and epithelial–mesenchymal transition

Pterostilbene prevents hepatocyte EMT in fructose-induced liver fibrosis through suppressing miR-34a/Sirt1/p53 and TGF-β1/Smads signaling

(2019) Lin Song et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nicotinamide riboside protects against liver fibrosis induced by CCl4 via regulating the acetylation of Smads signaling pathway

(2019) Rui Jiang et al.   LIFE SCIENCES

TGF-β in fibrosis by acting as a conductor for contractile properties of myofibroblasts

(2019) Alexandre Vallée et al.   Cell and Bioscience

Extracellular Superoxide Dismutase Attenuates Renal Oxidative Stress Through the Activation of Adenosine Monophosphate-Activated Protein Kinase in Diabetic Nephropathy

(2018) Yu Ah Hong et al.   ANTIOXIDANTS & REDOX SIGNALING

SIRT1 antagonizes liver fibrosis by blocking hepatic stellate cell activation in mice

(2018) Min Li et al.   FASEB JOURNAL

Extracellular superoxide dismutase 3 (SOD3) regulates oxidative stress at the vitreoretinal interface

(2018) Katherine J. Wert et al.   FREE RADICAL BIOLOGY AND MEDICINE

Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis

(2018) Huanyu Zhao et al.   PHARMACOLOGICAL RESEARCH

miR-133b and miR-199b knockdown attenuate TGF-β1-induced epithelial to mesenchymal transition and renal fibrosis by targeting SIRT1 in diabetic nephropathy

(2018) Zhiqiang Sun et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy

(2018) Gaëtan Juban et al.   Cell Reports

AICAR-Induced AMPK Activation Inhibits the Noncanonical NF-κB Pathway to Attenuate Liver Injury and Fibrosis in BDL Rats

(2018) Haoyang Zhu et al.   Canadian Journal of Gastroenterology and Hepatology

The origin of fibrogenic myofibroblasts in fibrotic liver

(2017) Tatiana Kisseleva   HEPATOLOGY

Berberine suppresses LPS-induced inflammation through modulating Sirt1/NF-κB signaling pathway in RAW264.7 cells

(2017) Hao Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Aging aggravates alcoholic liver injury and fibrosis in mice by downregulating sirtuin 1 expression

(2017) Teresa Ramirez et al.   JOURNAL OF HEPATOLOGY

Glutamine inhibits CCl4 induced liver fibrosis in mice and TGF-β1 mediated epithelial–mesenchymal transition in mouse hepatocytes

(2016) Nirajan Shrestha et al.   FOOD AND CHEMICAL TOXICOLOGY

Controversies over the Epithelial-to-Mesenchymal Transition in Liver Fibrosis

(2016) Kojiro Taura et al.   Journal of Clinical Medicine

Transcriptional repression of SIRT1 by protein inhibitor of activated STAT 4 (PIAS4) in hepatic stellate cells contributes to liver fibrosis

(2016) Lina Sun et al.   Scientific Reports

Silent information regulator 1 (SIRT1) ameliorates liver fibrosis via promoting activated stellate cell apoptosis and reversion

(2015) Yuting Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Protective effect of Actiniopteris radiata (Sw.) Link. against CCl4 induced oxidative stress in albino rats

(2014) Manjunath Manubolu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Origin of myofibroblasts in the fibrotic liver in mice

(2014) K. Iwaisako et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SIRT1 and other sirtuins in metabolism

(2014) Hung-Chun Chang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Deletion of SIRT1 From Hepatocytes in Mice Disrupts Lipin-1 Signaling and Aggravates Alcoholic Fatty Liver

(2013) Huquan Yin et al.   GASTROENTEROLOGY

The Protective Effect of Glycyrrhetinic Acid on Carbon Tetrachloride-Induced Chronic Liver Fibrosis in Mice via Upregulation of Nrf2

(2013) Shaoru Chen et al.   PLoS One

Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver injury

(2013) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

(2013) Ingmar Mederacke et al.   Nature Communications

Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK–SIRT1–PGC1α axis in db/db mice

(2012) M. Y. Kim et al.   DIABETOLOGIA

Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent

(2012) Tomonori Aoyama et al.   HEPATOLOGY

Fibrosis-dependent mechanisms of hepatocarcinogenesis

(2012) David Y. Zhang et al.   HEPATOLOGY

Epidermal Growth Factor-induced Vacuolar (H+)-ATPase Assembly

(2012) Yanqing Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis

(2011) Andrew S. Chu et al.   HEPATOLOGY

Saponins from Panax japonicus Protect Against Alcohol-Induced Hepatic Injury in Mice by Up-regulating the Expression of GPX3, SOD1 and SOD3

(2010) Y.-G. Li et al.   ALCOHOL AND ALCOHOLISM

Sirt1 inhibition promotes in vivo arterial thrombosis and tissue factor expression in stimulated cells

(2010) Alexander Breitenstein et al.   CARDIOVASCULAR RESEARCH

Genetic Labeling Does Not Detect Epithelial-to-Mesenchymal Transition of Cholangiocytes in Liver Fibrosis in Mice

(2010) David Scholten et al.   GASTROENTEROLOGY

The epithelial to mesenchymal transition in liver fibrosis: Here today, gone tomorrow?

(2010) Rebecca G. Wells   HEPATOLOGY

Regulation of superoxide dismutase genes: Implications in disease

(2009) Lu Miao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Epithelial-to-mesenchymal transitions in the liver

(2009) Steve S. Choi et al.   HEPATOLOGY

Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice

(2009) Kojiro Taura et al.   HEPATOLOGY

Extracellular superoxide dismutase regulates cardiac function and fibrosis

(2009) Corrine R. Kliment et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Extracellular Superoxide Dismutase in Pulmonary Fibrosis

(2007) Fei Gao et al.   ANTIOXIDANTS & REDOX SIGNALING

Evidence for the epithelial to mesenchymal transition in biliary atresia fibrosis

(2007) Rosalyn Díaz et al.   HUMAN PATHOLOGY