Histone demethylase JMJD2D promotes the self-renewal of liver cancer stem-like cells by enhancing EpCAM and Sox9 expression

Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling

(2020) Minghui Zhuo et al.   ONCOGENE

Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis

(2019) Wei Lu et al.   DEVELOPMENTAL CELL

H3K9 demethylase KDM4E is an epigenetic regulator for bovine embryonic development and a defective factor for nuclear reprogramming

(2018) Xin Liu et al.   DEVELOPMENT

Nuclear Receptor Nur77 Facilitates Melanoma Cell Survival under Metabolic Stress by Protecting Fatty Acid Oxidation

(2018) Xiao-xue Li et al.   MOLECULAR CELL

Genomic Profiling and Metabolic Homeostasis in Primary Liver Cancers

(2018) Julian A. Gingold et al.   TRENDS IN MOLECULAR MEDICINE

Histone demethylase KDM4D promotes gastrointestinal stromal tumor progression through HIF1β/VEGFA signalling

(2018) Fuqing Hu et al.   Molecular Cancer

Histone Demethylase JMJD2D Interacts with Beta-catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice

(2018) Kesong Peng et al.   GASTROENTEROLOGY

Epigenetics in cancer stem cells

(2017) Tan Boon Toh et al.   Molecular Cancer

Histone demethylase JMJD1A promotes urinary bladder cancer progression by enhancing glycolysis through coactivation of hypoxia inducible factor 1α

(2017) W Wan et al.   ONCOGENE

Sox9 regulates self-renewal and tumorigenicity by promoting symmetrical cell division of cancer stem cells in hepatocellular carcinoma

(2016) Chungang Liu et al.   HEPATOLOGY

Long non-coding RNA DILC regulates liver cancer stem cells via IL-6/STAT3 axis

(2016) Xue Wang et al.   JOURNAL OF HEPATOLOGY

H3K9me3 demethylase Kdm4d facilitates the formation of pre-initiative complex and regulates DNA replication

(2016) Rentian Wu et al.   NUCLEIC ACIDS RESEARCH

Steroid Receptor Coactivator 1 Promotes Human Hepatocellular Carcinoma Progression by Enhancing Wnt/β-Catenin Signaling

(2015) Zhangwei Tong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Notch, Hedgehog and Wnt pathways in cancer stem cells: clinical update

(2015) Naoko Takebe et al.   Nature Reviews Clinical Oncology

C8orf4 negatively regulates self-renewal of liver cancer stem cells via suppression of NOTCH2 signalling

(2015) Pingping Zhu et al.   Nature Communications

Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma

(2015) Kathleen M. Capaccione et al.   Oncotarget

Epigenetics of cancer stem cells: Pathways and therapeutics

(2014) Samriddhi Shukla et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Epidemiology of hepatocellular carcinoma in the United States: Where are we? Where do we go?

(2014) Hashem B. El-Serag et al.   HEPATOLOGY

Tackling the cancer stem cells — what challenges do they pose?

(2014) Diwakar R. Pattabiraman et al.   NATURE REVIEWS DRUG DISCOVERY

PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair

(2014) H. Khoury-Haddad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KDM4/JMJD2 Histone Demethylases: Epigenetic Regulators in Cancer Cells

(2013) W. L. Berry et al.   CANCER RESEARCH

Twist2 promotes self-renewal of liver cancer stem-like cells by regulating CD24

(2013) Allan Yi Liu et al.   CARCINOGENESIS

OV6+ tumor-initiating cells contribute to tumor progression and invasion in human hepatocellular carcinoma

(2012) Wen Yang et al.   JOURNAL OF HEPATOLOGY

Chromatin-modifying enzymes as modulators of reprogramming

(2012) Tamer T. Onder et al.   NATURE

Novel Histone Demethylase LSD1 Inhibitors Selectively Target Cancer Cells with Pluripotent Stem Cell Properties

(2011) J. Wang et al.   CANCER RESEARCH

The cancer stem cell: premises, promises and challenges

(2011) Hans Clevers   NATURE MEDICINE

Twist2 contributes to breast cancer progression by promoting an epithelial–mesenchymal transition and cancer stem-like cell self-renewal

(2011) X Fang et al.   ONCOGENE

CD13 is a therapeutic target in human liver cancer stem cells

(2010) Naotsugu Haraguchi et al.   JOURNAL OF CLINICAL INVESTIGATION

EpCAM, a new marker for cancer stem cells in hepatocellular carcinoma

(2009) Benoit Terris et al.   JOURNAL OF HEPATOLOGY

Hepatic Stem-like Phenotype and Interplay of Wnt/β-Catenin and Myc Signaling in Aggressive Childhood Liver Cancer

(2008) Stefano Cairo et al.   CANCER CELL

Significance of CD90+ Cancer Stem Cells in Human Liver Cancer

(2008) Zhen Fan Yang et al.   CANCER CELL