ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity

Adenine Nucleotide Translocase Is Acetylated in Vivo in Human Muscle: Modeling Predicts a Decreased ADP Affinity and Altered Control of Oxidative Phosphorylation

(2014) Clinton Mielke et al.   BIOCHEMISTRY

Opening of the mitochondrial permeability transition pore links mitochondrial dysfunction to insulin resistance in skeletal muscle

(2013) E.P. Taddeo et al.   Molecular Metabolism

High Oxidative Capacity Due to Chronic Exercise Training Attenuates Lipid-Induced Insulin Resistance

(2012) E. Phielix et al.   DIABETES

Targeting of mitochondrial reactive oxygen species production does not avert lipid-induced insulin resistance in muscle tissue from mice

(2012) S. Paglialunga et al.   DIABETOLOGIA

Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals

(2012) Naresh C Bal et al.   NATURE MEDICINE

Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice

(2011) Miranda Nabben et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Remodeling Lipid Metabolism and Improving Insulin Responsiveness in Human Primary Myotubes

(2011) Lauren M. Sparks et al.   PLoS One

Cold tolerance of UCP1-ablated mice: A skeletal muscle mitochondria switch toward lipid oxidation with marked UCP3 up-regulation not associated with increased basal, fatty acid- or ROS-induced uncoupling or enhanced GDP effects

(2010) Irina G. Shabalina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Palmitate-induced skeletal muscle insulin resistance does not require NF-κB activation

(2010) Pascal P. H. Hommelberg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance

(2010) J. Hoeks et al.   DIABETES

Increased Reactive Oxygen Species Production and Lower Abundance of Complex I Subunits and Carnitine Palmitoyltransferase 1B Protein Despite Normal Mitochondrial Respiration in Insulin-Resistant Human Skeletal Muscle

(2010) N. Lefort et al.   DIABETES

Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals

(2010) E. Phielix et al.   DIABETOLOGIA

Increased subsarcolemmal lipids in type 2 diabetes: effect of training on localization of lipids, mitochondria, and glycogen in sedentary human skeletal muscle

(2009) Joachim Nielsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity

(2009) R. C.R. Meex et al.   DIABETES

Effect of Short-Term Free Fatty Acids Elevation on Mitochondrial Function in Skeletal Muscle of Healthy Individuals

(2009) Alberto O. Chavez et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

(2008) E. Phielix et al.   DIABETES

The effect of UCP3 overexpression on mitochondrial ROS production in skeletal muscle of young versus aged mice

(2008) Miranda Nabben et al.   FEBS LETTERS

Mitochondrial function, content and ROS production in rat skeletal muscle: Effect of high-fat feeding

(2008) Joris Hoeks et al.   FEBS LETTERS

Increased substrate oxidation and mitochondrial uncoupling in skeletal muscle of endurance-trained individuals

(2008) D. E. Befroy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA