Targeting of mitochondrial reactive oxygen species production does not avert lipid-induced insulin resistance in muscle tissue from mice

Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents

(2016) Vladimir N. Anisimov et al.   Aging-US

Normal adaptations to exercise despite protection against oxidative stress

(2011) Kazuhiko Higashida et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

High-sucrose diet increases ROS generation, FFA accumulation, UCP2 level, and proton leak in liver mitochondria

(2011) Angélica Ruiz-Ramírez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fatty acids acutely enhance insulin-induced oxidative stress and cause insulin resistance by increasing mitochondrial reactive oxygen species (ROS) generation and nuclear factor-κB inhibitor (IκB)–nuclear factor-κB (NFκB) activation in rat muscle, in the absence of mitochondrial dysfunction

(2011) R. Barazzoni et al.   DIABETOLOGIA

Enhanced lipid-but not carbohydrate-supported mitochondrial respiration in skeletal muscle of PGC-1α overexpressing mice

(2011) Joris Hoeks et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress

(2010) Larysa Yuzefovych et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cold tolerance of UCP1-ablated mice: A skeletal muscle mitochondria switch toward lipid oxidation with marked UCP3 up-regulation not associated with increased basal, fatty acid- or ROS-induced uncoupling or enhanced GDP effects

(2010) Irina G. Shabalina et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Targeted Expression of Catalase to Mitochondria Prevents Age-Associated Reductions in Mitochondrial Function and Insulin Resistance

(2010) Hui-Young Lee et al.   Cell Metabolism

Palmitate-induced skeletal muscle insulin resistance does not require NF-κB activation

(2010) Pascal P. H. Hommelberg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Increased Reactive Oxygen Species Production and Lower Abundance of Complex I Subunits and Carnitine Palmitoyltransferase 1B Protein Despite Normal Mitochondrial Respiration in Insulin-Resistant Human Skeletal Muscle

(2010) N. Lefort et al.   DIABETES

Antioxidant Supplementation Reduces Skeletal Muscle Mitochondrial Biogenesis

(2010) NATALIE A. STROBEL et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Oxidative stress in skeletal muscle impairs mitochondrial respiration and limits exercise capacity in type 2 diabetic mice

(2009) Takashi Yokota et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 2. Treatment of some ROS- and Age-related diseases (heart arrhythmia, heart infarctions, kidney ischemia, and stroke)

(2009) L. E. Bakeeva et al.   BIOCHEMISTRY-MOSCOW

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 4. Age-related eye disease. SkQ1 returns vision to blind animals

(2009) V. V. Neroev et al.   BIOCHEMISTRY-MOSCOW

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 5. SkQ1 prolongs lifespan and prevents development of traits of senescence

(2009) V. N. Anisimov et al.   BIOCHEMISTRY-MOSCOW

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: Synthesis and in vitro studies

(2009) Y. N. Antonenko et al.   BIOCHEMISTRY-MOSCOW

Reactive Oxygen Species Enhance Insulin Sensitivity

(2009) Kim Loh et al.   Cell Metabolism

Mitochondrial reactive oxygen species generation in obese non-diabetic and type 2 diabetic participants

(2009) M. A. Abdul-Ghani et al.   DIABETOLOGIA

Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation

(2009) Erich B. Tahara et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Adaptations in Mitochondrial Function Parallel, but Fail to Rescue, the Transition to Severe Hyperglycemia and Hyperinsulinemia: A Study in Zucker Diabetic Fatty Rats

(2009) Ellen Lenaers et al.   Obesity

Insulin resistance is a cellular antioxidant defense mechanism

(2009) K. L. Hoehn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antioxidants prevent health-promoting effects of physical exercise in humans

(2009) M. Ristow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An attempt to prevent senescence: A mitochondrial approach

(2008) Vladimir P. Skulachev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

IRS1-Independent Defects Define Major Nodes of Insulin Resistance

(2008) Kyle L. Hoehn et al.   Cell Metabolism

Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

(2008) E. Phielix et al.   DIABETES

Mitochondrial function, content and ROS production in rat skeletal muscle: Effect of high-fat feeding

(2008) Joris Hoeks et al.   FEBS LETTERS