Pyrrolidinyl Synthetic Cathinones α-PHP and 4F-α-PVP Metabolite Profiling Using Human Hepatocyte Incubations

Designer drugs: mechanism of action and adverse effects

(2020) Dino Luethi et al.   ARCHIVES OF TOXICOLOGY

A review of synthetic cathinone-related fatalities from 2017 to 2020

(2020) Nunzia La Maida et al.   THERAPEUTIC DRUG MONITORING

New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites

(2019) Xingxing Diao et al.   Frontiers in Chemistry

A multi-analyte LC–MS/MS method for screening and quantification of 16 synthetic cathinones in hair: Application to postmortem cases

(2019) Francesca Freni et al.   FORENSIC SCIENCE INTERNATIONAL

Postmortem concentrations of the synthetic opioid U-47700 in 26 fatalities associated with the drug

(2019) Helena Fels et al.   FORENSIC SCIENCE INTERNATIONAL

Para-Halogenation Affects Monoamine Transporter Inhibition Properties and Hepatocellular Toxicity of Amphetamines and Methcathinones

(2019) Dino Luethi et al.   Frontiers in Pharmacology

Testing Unconventional Matrices to Monitor for Prenatal Exposure to Heroin, Cocaine, Amphetamines, Synthetic Cathinones, and Synthetic Opioids

(2019) Jeremy Carlier et al.   THERAPEUTIC DRUG MONITORING

The synthetic cathinone α-pyrrolidinovalerophenone (α-PVP): pharmacokinetic and pharmacodynamic clinical and forensic aspects

(2018) Leandro Nóbrega et al.   DRUG METABOLISM REVIEWS

Different in vitro and in vivo tools for elucidating the human metabolism of alpha-cathinone-derived drugs of abuse

(2018) Sascha K. Manier et al.   Drug Testing and Analysis

Metabolism of the new synthetic cannabinoid EG-018 in human hepatocytes by high-resolution mass spectrometry

(2018) Xingxing Diao et al.   Forensic Toxicology

Metabolism of α-PHP and α-PHPP in humans and the effects of alkyl chain lengths on the metabolism of α-pyrrolidinophenone-type designer drugs

(2018) Shuntaro Matsuta et al.   Forensic Toxicology

OUP accepted manuscript

(2018)   JOURNAL OF ANALYTICAL TOXICOLOGY

Synthetic cannabinoid BB-22 (QUCHIC): Human hepatocytes metabolism with liquid chromatography-high resolution mass spectrometry detection

(2018) Jeremy Carlier et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Fetal death associated with the use of 3,4-MDPHP and α-PHP

(2018) Piotr Adamowicz et al.   CLINICAL TOXICOLOGY

Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters

(2018) Amy J. Eshleman et al.   PSYCHOPHARMACOLOGY

In vitro metabolism of new synthetic cannabinoid SDB-006 in human hepatocytes by high-resolution mass spectrometry

(2017) Xingxing Diao et al.   Forensic Toxicology

First metabolic profile of PV8, a novel synthetic cathinone, in human hepatocytes and urine by high-resolution mass spectrometry

(2016) Madeleine J. Swortwood et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Approaches, Challenges, and Advances in Metabolism of New Synthetic Cannabinoids and Identification of Optimal Urinary Marker Metabolites

(2016) X Diao et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

25C-NBOMe and 25I-NBOMe metabolite studies in human hepatocytes, in vivo mouse and human urine with high-resolution mass spectrometry

(2016) Ariane Wohlfarth et al.   Drug Testing and Analysis

Identification and analytical characterization of nine synthetic cathinone derivatives N -ethylhexedrone, 4-Cl-pentedrone, 4-Cl-α -EAPP, propylone, N -ethylnorpentylone, 6-MeO-bk-MDMA, α -PiHP, 4-Cl-α -PHP, and 4-F-α -PHP

(2016) Cuimei Liu et al.   Drug Testing and Analysis

GC–MS analysis of the designer drug α-pyrrolidinovalerophenone and its metabolites in urine and blood in an acute poisoning case

(2016) Marcel Grapp et al.   FORENSIC SCIENCE INTERNATIONAL

In vitro and in vivo human metabolism of a new synthetic cannabinoid NM-2201 (CBL-2201)

(2016) Xingxing Diao et al.   Forensic Toxicology

In vitro, in vivo and in silico metabolic profiling of α-pyrrolidinopentiothiophenone, a novel thiophene stimulant

(2016) Madeleine J Swortwood et al.   Bioanalysis

Thermal Degradation of Small Molecules: A Global Metabolomic Investigation

(2015) Mingliang Fang et al.   ANALYTICAL CHEMISTRY

Quantitative structure-activity relationship analysis of the pharmacology ofpara-substituted methcathinone analogues

(2015) J S Bonano et al.   BRITISH JOURNAL OF PHARMACOLOGY

Metabolic characterization of AH-7921, a synthetic opioid designer drug:in vitrometabolic stability assessment and metabolite identification, evaluation ofin silicoprediction, andin vivoconfirmation

(2015) Ariane Wohlfarth et al.   Drug Testing and Analysis

Metabolism of the designer drug α-pyrrolidinobutiophenone (α-PBP) in humans: Identification and quantification of the phase I metabolites in urine

(2015) Shuntaro Matsuta et al.   FORENSIC SCIENCE INTERNATIONAL

Urinary excretion and metabolism of the α-pyrrolidinophenone designer drug 1-phenyl-2-(pyrrolidin-1-yl)octan-1-one (PV9) in humans

(2015) Noriaki Shima et al.   Forensic Toxicology

4-Methoxy-α-PVP: in silico prediction, metabolic stability, and metabolite identification by human hepatocyte incubation and high-resolution mass spectrometry

(2015) Kayla N. Ellefsen et al.   Forensic Toxicology

Thermal Degradation of Synthetic Cathinones: Implications for Forensic Toxicology

(2015) Sarah Kerrigan et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

Identification of phase I and II metabolites of the new designer drugα-pyrrolidinohexiophenone (α-PHP) in human urine by liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS)

(2015) Michael Paul et al.   JOURNAL OF MASS SPECTROMETRY

Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products

(2014) Nahoko Uchiyama et al.   FORENSIC SCIENCE INTERNATIONAL

Chemical analysis of a benzofuran derivative, 2-(2-ethylaminopropyl)benzofuran (2-EAPB), eight synthetic cannabinoids, five cathinone derivatives, and five other designer drugs newly detected in illegal products

(2014) Nahoko Uchiyama et al.   Forensic Toxicology

Thermal degradation of α-pyrrolidinopentiophenone during injection in gas chromatography/mass spectrometry

(2013) Kenji Tsujikawa et al.   FORENSIC SCIENCE INTERNATIONAL

Metabolism of the newly encountered designer drug α-pyrrolidinovalerophenone in humans: identification and quantitation of urinary metabolites

(2013) Noriaki Shima et al.   Forensic Toxicology

New cathinone-derived designer drugs 3-bromomethcathinone and 3-fluoromethcathinone: studies on their metabolism in rat urine and human liver microsomes using GC-MS and LC-high-resolution MS and their detectability in urine

(2012) Markus R. Meyer et al.   JOURNAL OF MASS SPECTROMETRY

New designer drug α‐pyrrolidinovalerophenone (PVP): studies on its metabolism and toxicological detection in rat urine using gas chromatographic/mass spectrometric techniques

(2009) Christoph Sauer et al.   JOURNAL OF MASS SPECTROMETRY