Kaempferol Inhibits Zearalenone-Induced Oxidative Stress and Apoptosis via the PI3K/Akt-Mediated Nrf2 Signaling Pathway: In Vitro and In Vivo Studies

The PI3K/AKT/mTOR signaling pathway in osteoarthritis: a narrative review

(2020) K. Sun et al.   OSTEOARTHRITIS AND CARTILAGE

Chlorogenic acid rescues zearalenone induced injury to mouse ovarian granulosa cells

(2020) YanYan Yi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Lonicera caerulea L. Polyphenols Alleviate Oxidative Stress‐Induced Intestinal Environment Imbalance and Lipopolysaccharide‐Induced Liver Injury in HFD‐Fed Rats by Regulating the Nrf2/HO‐1/NQO1 and MAPK Pathways

(2020) Bin Li et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Heme oxygenase-1 alleviated non-alcoholic fatty liver disease via suppressing ROS-dependent endoplasmic reticulum stress

(2020) Dongdong Li et al.   LIFE SCIENCES

Suppression of LPS-Induced Inflammation by Chalcone Flavokawain A through Activation of Nrf2/ARE-Mediated Antioxidant Genes and Inhibition of ROS/NFκB Signaling Pathways in Primary Splenocytes

(2020) Hsin-Ling Yang et al.   Oxidative Medicine and Cellular Longevity

Zearalenone-Induced Interaction between PXR and Sp1 Increases Binding of Sp1 to a Promoter Site of the eNOS, Decreasing Its Transcription and NO Production in BAECs

(2020) Hyeon-Ju Lee et al.   Toxins

Effects of Deoxynivalenol and Zearalenone on the Histology and Ultrastructure of Pig Liver

(2020) Natalia Skiepko et al.   Toxins

Kaempferol Protects Blood Vessels From Damage Induced by Oxidative Stress and Inflammation in Association With the Nrf2/HO-1 Signaling Pathway

(2020) He Yao et al.   Frontiers in Pharmacology

Grape Seed Proanthocyanidin Extract Alleviates AflatoxinB1-Induced Immunotoxicity and Oxidative Stress via Modulation of NF-κB and Nrf2 Signaling Pathways in Broilers

(2019) Shahid Rajput et al.   Toxins

Sulforaphane potentially attenuates arsenic-induced nephrotoxicity via the PI3K/Akt/Nrf2 pathway in albino Wistar rats

(2019) Shanmugam Thangapandiyan et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Kaempferol: A Key Emphasis to Its Anticancer Potential

(2019) Muhammad Imran et al.   MOLECULES

PI3K/AKT inhibitors aggravate death receptor-mediated hepatocyte apoptosis and liver injury

(2019) Wei Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Resveratrol Attenuates Oxidative Stress-Induced Intestinal Barrier Injury through PI3K/Akt-Mediated Nrf2 Signaling Pathway

(2019) Yu Zhuang et al.   Oxidative Medicine and Cellular Longevity

Zearalenone Induces Endoplasmic Reticulum Stress and Modulates the Expression of Phase I/II Enzymes in Human Liver Cells

(2019) Jee Eun Yoon et al.   Toxins

Zerumbone protects human skin keratinocytes against UVA-irradiated damages through Nrf2 induction

(2018) Hsin-Ling Yang et al.   BIOCHEMICAL PHARMACOLOGY

OUP accepted manuscript

(2018)   JOURNAL OF NUTRITION

Ganglioside GM1 protects against high altitude cerebral edema in rats by suppressing the oxidative stress and inflammatory response via the PI3K/AKT-Nrf2 pathway

(2018) Gu Gong et al.   MOLECULAR IMMUNOLOGY

Proanthocyanidins Protect Epithelial Cells from Zearalenone-Induced Apoptosis via Inhibition of Endoplasmic Reticulum Stress-Induced Apoptosis Pathways in Mouse Small Intestines

(2018) Miao Long et al.   MOLECULES

Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice

(2018) Ming-Shiun Tsai et al.   TOXICOLOGY LETTERS

Mycotoxins and oxidative stress: where are we?

(2018) E.O. da Silva et al.   World Mycotoxin Journal

Protective Effect of Fisetin Against angiotensin II-induced Apoptosis by Activation of IGF-IR-PI3K-Akt Signaling in H9c2 cells and Spontaneous hypertension rats

(2018) Bih-Cheng Chen et al.   PHYTOMEDICINE

Protective effects of selenium against zearalenone-induced apoptosis in chicken spleen lymphocyte via an endoplasmic reticulum stress signaling pathway

(2018) Yinxia Xiao et al.   CELL STRESS & CHAPERONES

Chalcone flavokawain A attenuates TGF ‐β1‐induced fibrotic pathology via inhibition of ROS /Smad3 signaling pathways and induction of Nrf2/ ARE ‐mediated antioxidant genes in vascular smooth muscle cells

(2018) You‐Cheng Hseu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Protection of Kaempferol on Oxidative Stress-Induced Retinal Pigment Epithelial Cell Damage

(2018) Weiwei Du et al.   Oxidative Medicine and Cellular Longevity

Zearalenone causes embryotoxicity and induces oxidative stress and apoptosis in differentiated human embryonic stem cells

(2018) Hanwen Cao et al.   TOXICOLOGY IN VITRO

Toxicity of zearalenone on the intestines of pregnant sows and their offspring and alleviation with modified halloysite nanotubes

(2017) Min Liu et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Natural Dietary Supplementation of Anthocyanins via PI3K/Akt/Nrf2/HO-1 Pathways Mitigate Oxidative Stress, Neurodegeneration, and Memory Impairment in a Mouse Model of Alzheimer’s Disease

(2017) Tahir Ali et al.   MOLECULAR NEUROBIOLOGY

Oxidative Stress in Liver Diseases: Pathogenesis, Prevention, and Therapeutics

(2017) Ravirajsinh N. Jadeja et al.   Oxidative Medicine and Cellular Longevity

Protective effects of ellagic acid against tetrachloride-induced cirrhosis in mice through the inhibition of reactive oxygen species formation and angiogenesis

(2017) Yuan Ding et al.   Experimental and Therapeutic Medicine

Cytotoxic effects of zearalenone and its metabolites and antioxidant cell defense in CHO-K1 cells

(2016) Elena Tatay et al.   FOOD AND CHEMICAL TOXICOLOGY

Nrf2 knockdown attenuates the ameliorative effects of ligustrazine on hepatic fibrosis by targeting hepatic stellate cell transdifferentiation

(2016) Chunfeng Lu et al.   TOXICOLOGY

Biological and physiological role of reactive oxygen species - the good, the bad and the ugly

(2015) L. Zuo et al.   Acta Physiologica

Physio-Chemical Changes During Repeated Frying of Cooked Oil: A Review

(2015) Prakash Kumar Nayak et al.   JOURNAL OF FOOD BIOCHEMISTRY

Zearalenone induces oxidative damage involving Keap1/Nrf2/HO-1 pathway in hepatic L02 cells

(2015) Kejia Wu et al.   Molecular & Cellular Toxicology

Kaempferol, a potential cytostatic and cure for inflammatory disorders

(2014) Peramaiyan Rajendran et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model

(2014) Muthu K. Shanmugam et al.   MOLECULAR CARCINOGENESIS

Effects of zearalenone on oxidative stress and inflammation in weanling piglets

(2013) Daniela E. Marin et al.   FOOD AND CHEMICAL TOXICOLOGY

Antioxidant effects of diallyl trisulfide on high glucose-induced apoptosis are mediated by the PI3K/Akt-dependent activation of Nrf2 in cardiomyocytes

(2013) Cheng-Yen Tsai et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner

(2011) Janel E. Le Belle et al.   Cell Stem Cell

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genotoxic and Carcinogenic Risks Associated with the Consumption of Repeatedly Boiled Sunflower Oil

(2010) Smita Srivastava et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effects of zearalenone and its derivatives on the innate immune response of swine

(2010) Daniela E. Marin et al.   TOXICON

Mycotoxins in fruits and their processed products: Analysis, occurrence and health implications

(2010) María L. Fernández-Cruz et al.   Journal of Advanced Research

Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: Novel cytoprotective mechanism against oxidative damage

(2008) Ju Hee Lim et al.   PHARMACOLOGICAL RESEARCH