Protocatechualdehyde protects oxygen-glucose deprivation/reoxygenation-induced myocardial injury via inhibiting PERK/ATF6α/IRE1α pathway

Up-Regulation of Trem2 Inhibits Hippocampal Neuronal Apoptosis and Alleviates Oxidative Stress in Epilepsy via the PI3K/Akt Pathway in Mice

(2019) Ai-Hua Liu et al.   Neuroscience Bulletin

Protocatechualdehyde reduces myocardial fibrosis by directly targeting conformational dynamics of collagen

(2019) Yan-Jun Wan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Regulation of PERK expression by FOXO3: a vulnerability of drug-resistant cancer cells

(2019) Glowi Alasiri et al.   ONCOGENE

Hes1 Knockdown Exacerbates Ischemic Stroke Following tMCAO by Increasing ER Stress-Dependent Apoptosis via the PERK/eIF2α/ATF4/CHOP Signaling Pathway

(2019) Yueyong Li et al.   Neuroscience Bulletin

Cardiovascular Disease, Aging, and Clonal Hematopoiesis

(2019) Megan A. Evans et al.   Annual Review of Pathology-Mechanisms of Disease

REDD1 knockdown protects H9c2 cells against myocardial ischemia/reperfusion injury through Akt/mTORC1/Nrf2 pathway-ameliorated oxidative stress: An in vitro study

(2019) Peng Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CTCF inhibits endoplasmic reticulum stress and apoptosis in cardiomyocytes by upregulating RYR2 via inhibiting S100A1

(2019) Zhu Zeng et al.   LIFE SCIENCES

Hydrogen Sulfide Protects Human Cardiac Fibroblasts Against H2O2-induced Injury Through Regulating Autophagy-Related Proteins

(2018) Ao Feng et al.   CELL TRANSPLANTATION

CRTH2 promotes endoplasmic reticulum stress‐induced cardiomyocyte apoptosis through m‐calpain

(2018) Shengkai Zuo et al.   EMBO Molecular Medicine

Targeting HMGB1 ameliorates cardiac fibrosis through restoring TLR2-mediated autophagy suppression in myocardial fibroblasts

(2018) Ri-Na Wu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

ROS signaling and ER stress in cardiovascular disease

(2018) Cristhiaan D. Ochoa et al.   MOLECULAR ASPECTS OF MEDICINE

An Integrated Proteomics and Bioinformatics Approach Reveals the Anti-inflammatory Mechanism of Carnosic Acid

(2018) Li-Chao Wang et al.   Frontiers in Pharmacology

Deficiency of PKD2L1 (TRPP3) Exacerbates Pathological Cardiac Hypertrophy by Augmenting NCX1-Mediated Mitochondrial Calcium Overload

(2018) Zongshi Lu et al.   Cell Reports

A Splicing-Independent Function of RBM10 Controls Specific 3′ UTR Processing to Regulate Cardiac Hypertrophy

(2018) Nimmy Mohan et al.   Cell Reports

Protein disulfide-isomerase A3 significantly reduces ischemia-induced damage by reducing oxidative and endoplasmic reticulum stress

(2018) Dae Young Yoo et al.   NEUROCHEMISTRY INTERNATIONAL

Chikusetsu saponin IVa attenuates isoprenaline-induced myocardial fibrosis in mice through activation autophagy mediated by AMPK/mTOR/ULK1 signaling

(2018) Luopei Wang et al.   PHYTOMEDICINE

Management of Ventricular Arrhythmias in Patients With Advanced Heart Failure

(2017) Pasquale Santangeli et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Alginate oligosaccharide alleviates myocardial reperfusion injury by inhibiting nitrative and oxidative stress and endoplasmic reticulum stress-mediated apoptosis

(2017) Jun-Jie Guo et al.   Drug Design Development and Therapy

The fibrosis-cell death axis in heart failure

(2016) A. Piek et al.   HEART FAILURE REVIEWS

Protocatechualdehyde Protects Against Cerebral Ischemia-Reperfusion-Induced Oxidative Injury Via Protein Kinase Cε/Nrf2/HO-1 Pathway

(2016) Chao Guo et al.   MOLECULAR NEUROBIOLOGY

Protocatechualdehyde Induces S-Phase Arrest and Apoptosis by Stimulating the p27KIP1-Cyclin A/D1-CDK2 and Mitochondrial Apoptotic Pathways in HT-29 Cells

(2016) Shi Zhong et al.   MOLECULES

Aldose Reductase Acts as a Selective Derepressor of PPARγ and the Retinoic Acid Receptor

(2016) Devi Thiagarajan et al.   Cell Reports

The Role of Endoplasmic Reticulum Stress in Human Pathology

(2015) Scott A. Oakes et al.   Annual Review of Pathology-Mechanisms of Disease

Molecular switches under TGFβ signalling during progression from cardiac hypertrophy to heart failure

(2015) J Heger et al.   BRITISH JOURNAL OF PHARMACOLOGY

Olmesartan restores the protective effect of remote ischemic perconditioning against myocardial ischemia/reperfusion injury in spontaneously hypertensive rats

(2015) X Lu et al.   Clinics

Protosappanin B protects PC12 cells against oxygen–glucose deprivation-induced neuronal death by maintaining mitochondrial homeostasis via induction of ubiquitin-dependent p53 protein degradation

(2015) Ke-Wu Zeng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The contribution of activating transcription factor 3 to apoptosis of human colorectal cancer cells by protocatechualdehyde, a naturally occurring phenolic compound

(2014) Jeong Rak Lee et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Anticancer Activity of Protocatechualdehyde in Human Breast Cancer Cells

(2014) Jieun Choi et al.   JOURNAL OF MEDICINAL FOOD

G Protein-Coupled Estrogen Receptor-1 Is Involved in the Protective Effect of Protocatechuic Aldehyde against Endothelial Dysfunction

(2014) Byung Soo Kong et al.   PLoS One

Protein disulfide isomerase in thrombosis and vascular inflammation

(2013) J. Cho   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Protocatechualdehyde possesses anti-cancer activity through downregulating cyclin D1 and HDAC2 in human colorectal cancer cells

(2012) Jin Boo Jeong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-inflammatory Effect of Protocatechuic Aldehyde on Myocardial Ischemia/Reperfusion Injury In Vivo and In Vitro

(2012) Guo Wei et al.   INFLAMMATION

In Vitro Antioxidant and Anti-Inflammatory Activities of Protocatechualdehyde Isolated from Phellinus gilvus

(2011) Zhi-Qiang CHANG et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Molecular Mechanisms Regulating Oxidative Activity of the Ero1 Family in the Endoplasmic Reticulum

(2010) Timothy J. Tavender et al.   ANTIOXIDANTS & REDOX SIGNALING

Antimicrobial and Antioxidative Activities of Bioactive Constituents from Hydnophytum formicarum Jack.

(2008) Supaluk Prachayasittikul et al.   MOLECULES

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS