Redox activation of ATM enhances GSNOR translation to sustain mitophagy and tolerance to oxidative stress

Mitophagy contributes to alpha-tocopheryl succinate toxicity in GSNOR-deficient hepatocellular carcinoma

(2020) Salvatore Rizza et al.   BIOCHEMICAL PHARMACOLOGY

ATM ‐ CHK 2‐Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress

(2020) Qi‐Qiang Guo et al.   EMBO JOURNAL

Mitochondria at the crossroads of ATM-mediated stress signaling and regulation of reactive oxygen species

(2020) Ji-Hoon Lee et al.   Redox Biology

Denitrosylate and live longer: how ADH5/GSNOR links mitophagy to aging

(2018) Salvatore Rizza et al.   Autophagy

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

(2018) Mario Mauthe et al.   Autophagy

S-nitrosylation drives cell senescence and aging in mammals by controlling mitochondrial dynamics and mitophagy

(2018) Salvatore Rizza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity

(2018) Yichong Zhang et al.   Science Signaling

ATM directs DNA damage responses and proteostasis via genetically separable pathways

(2018) Ji-Hoon Lee et al.   Science Signaling

Mitochondrial redox sensing by the kinase ATM maintains cellular antioxidant capacity

(2018) Yichong Zhang et al.   Science Signaling

ATM directs DNA damage responses and proteostasis via genetically separable pathways

(2018) Ji-Hoon Lee et al.   Science Signaling

40 Years of Research Put p53 in Translation

(2018) Virginie Marcel et al.   Cancers

Chronicles of a reductase: Biochemistry, genetics and physio-pathological role of GSNOR

(2017) Salvatore Rizza et al.   FREE RADICAL BIOLOGY AND MEDICINE

Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity

(2017) Zdenek Andrysik et al.   GENOME RESEARCH

Polysome-profiling in small tissue samples

(2017) Shuo Liang et al.   NUCLEIC ACIDS RESEARCH

Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53

(2017) Ishwarya Venkata Narayanan et al.   Scientific Reports

Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes

(2016) Irene Lopez-Fabuel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translation from the 5' untranslated region shapes the integrated stress response

(2016) S. R. Starck et al.   SCIENCE

Oxidized ATM promotes abnormal proliferation of breast CAFs through maintaining intracellular redox homeostasis and activating the PI3K-AKT, MEK-ERK, and Wnt-β-catenin signaling pathways

(2015) Shifu Tang et al.   CELL CYCLE

S-Nitrosoglutathione Reductase Plays Opposite Roles in SH-SY5Y Models of Parkinson’s Disease and Amyotrophic Lateral Sclerosis

(2015) Salvatore Rizza et al.   MEDIATORS OF INFLAMMATION

ATM functions at the peroxisome to induce pexophagy in response to ROS

(2015) Jiangwei Zhang et al.   NATURE CELL BIOLOGY

Nitric oxide synthase in innate and adaptive immunity: an update

(2015) Christian Bogdan   TRENDS IN IMMUNOLOGY

S-Nitrosoglutathione Reductase Deficiency-Induced S-Nitrosylation Results in Neuromuscular Dysfunction

(2014) Costanza Montagna et al.   ANTIOXIDANTS & REDOX SIGNALING

p53-directed translational control can shape and expand the universe of p53 target genes

(2014) S Zaccara et al.   CELL DEATH AND DIFFERENTIATION

Most hydrogen peroxide-induced histone H2AX phosphorylation is mediated by ATR and is not dependent on DNA double-strand breaks

(2014) T. Katsube et al.   JOURNAL OF BIOCHEMISTRY

Inducible nitric oxide synthase is a major intermediate in signaling pathways for the survival of plasma cells

(2014) Ankur S Saini et al.   NATURE IMMUNOLOGY

APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress

(2013) J. Willis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner

(2012) Magdalena Frank et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Prolonged Production of Reactive Oxygen Species in Response to B Cell Receptor Stimulation Promotes B Cell Activation and Proliferation

(2012) Matthew L. Wheeler et al.   JOURNAL OF IMMUNOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Mitochondrial dysfunction in ataxia-telangiectasia

(2011) Y. A. Valentin-Vega et al.   BLOOD

Forward light scatter is a simple measure of T-cell activation and proliferation but is not universally suited for doublet discrimination

(2011) Ralph M. Böhmer et al.   CYTOMETRY PART A

The redox stress hypothesis of aging

(2011) Rajindar S. Sohal et al.   FREE RADICAL BIOLOGY AND MEDICINE

The ATM protein kinase and cellular redox signaling: beyond the DNA damage response

(2011) Scott Ditch et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mitochondrial Reactive Oxygen Species Control T Cell Activation by Regulating IL-2 and IL-4 Expression: Mechanism of Ciprofloxacin-Mediated Immunosuppression

(2010) M. M. Kaminski et al.   JOURNAL OF IMMUNOLOGY

Lymphocyte Development Requires S-nitrosoglutathione Reductase

(2010) Z. Yang et al.   JOURNAL OF IMMUNOLOGY

Translational Regulation of Gene Expression during Conditions of Cell Stress

(2010) Keith A. Spriggs et al.   MOLECULAR CELL

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

SUnSET, a nonradioactive method to monitor protein synthesis

(2009) Enrico K Schmidt et al.   NATURE METHODS

An internal ribosomal entry site mediates redox-sensitive translation of Nrf2

(2009) Wenge Li et al.   NUCLEIC ACIDS RESEARCH