ATM functions at the peroxisome to induce pexophagy in response to ROS

To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate

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Peroxisomal Atg37 binds Atg30 or palmitoyl-CoA to regulate phagophore formation during pexophagy

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(2014) Alexandra Stolz et al.   NATURE CELL BIOLOGY

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MOF Phosphorylation by ATM Regulates 53BP1-Mediated Double-Strand Break Repair Pathway Choice

(2014) Arun Gupta et al.   Cell Reports

PEX5 and Ubiquitin Dynamics on Mammalian Peroxisome Membranes

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Redox-regulated Cargo Binding and Release by the Peroxisomal Targeting Signal Receptor, Pex5

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Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin

(2013) Naonobu Fujita et al.   JOURNAL OF CELL BIOLOGY

TSC on the peroxisome controls mTORC1

(2013) Don Benjamin et al.   NATURE CELL BIOLOGY

A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS

(2013) Jiangwei Zhang et al.   NATURE CELL BIOLOGY

Peroxisomes take shape

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Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1

(2013) D. N. Tripathi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria

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PEX5, the Shuttling Import Receptor for Peroxisomal Matrix Proteins, Is a Redox-Sensitive Protein

(2013) Oksana Apanasets et al.   TRAFFIC

Guidelines for the use and interpretation of assays for monitoring autophagy

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NBR1 acts as an autophagy receptor for peroxisomes

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Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex–dependent and –independent autophagy

(2012) Noor Gammoh et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

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Role of peroxisomes in ROS/RNS-metabolism: Implications for human disease

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Peroxisome assembly: matrix and membrane protein biogenesis

(2011) Changle Ma et al.   JOURNAL OF CELL BIOLOGY

A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

(2011) Sebastian A. Wagner et al.   MOLECULAR & CELLULAR PROTEOMICS

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

The ATM protein kinase and cellular redox signaling: beyond the DNA damage response

(2011) Scott Ditch et al.   TRENDS IN BIOCHEMICAL SCIENCES

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Superoxide is the major reactive oxygen species regulating autophagy

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Peroxisomal Dysfunction in Inflammatory Childhood White Matter Disorders: An Unexpected Contributor to Neuropathology

(2009) Inderjit Singh et al.   JOURNAL OF CHILD NEUROLOGY

Pex2 and Pex12 Function as Protein-Ubiquitin Ligases in Peroxisomal Protein Import

(2009) H. W. Platta et al.   MOLECULAR AND CELLULAR BIOLOGY

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

The peroxin Pex14p is involved in LC3-dependent degradation of mammalian peroxisomes

(2008) Sayuri Hara-Kuge et al.   EXPERIMENTAL CELL RESEARCH

Members of the E2D (UbcH5) Family Mediate the Ubiquitination of the Conserved Cysteine of Pex5p, the Peroxisomal Import Receptor

(2008) Cláudia P. Grou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

(2008) P. K. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PPARα: Mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators

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