Type I Natural Killer T Cells as Key Regulators of the Immune Response to Infectious Diseases

EGFR and TGF-β Signaling Pathways Cooperate to Mediate Chlamydia Pathogenesis

(2020) Joseph U. Igietseme et al.   INFECTION AND IMMUNITY

The emergence of a novel coronavirus (SARS-CoV-2), their biology and therapeutic options

(2020) Suliman Khan et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Innate Immune Components That Regulate the Pathogenesis and Resolution of hRSV and hMPV Infections

(2020) Catalina A. Andrade et al.   Viruses-Basel

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells

(2018) Mauro Gaya et al.   CELL

Immune evasion of the CD1d/NKT cell axis

(2018) Randy R Brutkiewicz et al.   CURRENT OPINION IN IMMUNOLOGY

Leishmania donovani mediated higher expression of CCL4 induces differential accumulation of CD4 + CD56 + NKT and CD8 + CD56 + NKT cells at infection site

(2018) Sarita Kumari et al.   CYTOKINE

Prevalence of Listeria spp. and characterization of Listeria monocytogenes isolated from food products in Tetouan, Morocco

(2018) Nadia Amajoud et al.   FOOD CONTROL

CD8 dim but not CD8 bright cells positive to CD56 dominantly express KIR and are cytotoxic during visceral leishmaniasis

(2018) Sarita Kumari et al.   HUMAN IMMUNOLOGY

Elevated Hepatic CD1d Levels Coincide with Invariant NKT Cell Defects in Chronic Hepatitis B Virus Infection

(2018) Xiaosheng Tan et al.   JOURNAL OF IMMUNOLOGY

Memory Follicular Helper Invariant NKT Cells Recognize Lipid Antigens on Memory B Cells and Elicit Antibody Recall Responses

(2018) Zuolong Chen et al.   JOURNAL OF IMMUNOLOGY

Leishmaniasis

(2018) Sakib Burza et al.   LANCET

Natural Killer T Cells and Mucosal-Associated Invariant T Cells in Lung Infections

(2018) François Trottein et al.   Frontiers in Immunology

Type II NKT Cells: An Elusive Population With Immunoregulatory Properties

(2018) Avadhesh Kumar Singh et al.   Frontiers in Immunology

Origin and evolution of pathogenic coronaviruses

(2018) Jie Cui et al.   NATURE REVIEWS MICROBIOLOGY

Human Metapneumovirus: Mechanisms and Molecular Targets Used by the Virus to Avoid the Immune System

(2018) Jorge A. Soto et al.   Frontiers in Immunology

GM-CSF and IL-4 produced by NKT cells inversely regulate IL-1β production by macrophages

(2017) Sehee Ahn et al.   IMMUNOLOGY LETTERS

Harnessing Invariant NKT Cells to Improve Influenza Vaccines: A Pig Perspective

(2017) Guan Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

New Insights Contributing to the Development of Effective Vaccines and Therapies to Reduce the Pathology Caused by hRSV

(2017) Nicolás Gálvez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Type II NKT Cells and Their Emerging Role in Health and Disease

(2017) Madhav V. Dhodapkar et al.   JOURNAL OF IMMUNOLOGY

Epithelial-derived TGF-β1 acts as a pro-viral factor in the lung during influenza A infection

(2017) L Denney et al.   Mucosal Immunology

The burden of hepatitis B virus (HBV) infection, genotypes and drug resistance mutations in human immunodeficiency virus-positive patients in Northwest Ethiopia

(2017) Tekalign Deressa et al.   PLoS One

Natural killer T cell sensitization during neonatal respiratory syncytial virus infection induces eosinophilic lung disease in re-infected adult mice

(2017) Seung Young Lee et al.   PLoS One

Invariant NKT cells promote skin wound healing by preventing a prolonged neutrophilic inflammatory response

(2017) Hiromasa Tanno et al.   WOUND REPAIR AND REGENERATION

Activation of invariant natural killer T cells stimulated with microbial α-mannosyl glycolipids

(2017) Michio Shimamura et al.   Scientific Reports

Taxonomy of the order Mononegavirales: update 2016

(2016) Claudio L. Afonso et al.   ARCHIVES OF VIROLOGY

NKT cells mediate the recruitment of neutrophils by stimulating epithelial chemokine secretion during colitis

(2016) Enyu Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hallmarks of Tissue-Resident Lymphocytes

(2016) Xiying Fan et al.   CELL

Activation of murine invariant NKT cells promotes susceptibility to candidiasis by IL-10 induced modulation of phagocyte antifungal activity

(2016) Norihiro Haraguchi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A potent adjuvant effect of a CD1d-binding NKT cell ligand in human immune system mice

(2016) Xiangming Li et al.   Expert Review of Vaccines

The dynamic changes of circulating invariant natural killer T cells during chronic hepatitis B virus infection

(2016) Man Li et al.   Hepatology International

The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013

(2016) Jeffrey D Stanaway et al.   LANCET

The global economic burden of dengue: a systematic analysis

(2016) Donald S Shepard et al.   LANCET INFECTIOUS DISEASES

Cytokine responses in primary and secondary respiratory syncytial virus infections

(2016) Kelechi Ugonna et al.   PEDIATRIC RESEARCH

Update on Human Rhinovirus and Coronavirus Infections

(2016) Stephen Greenberg   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

The Global Burden of Latent Tuberculosis Infection: A Re-estimation Using Mathematical Modelling

(2016) Rein M. G. J. Houben et al.   PLOS MEDICINE

Rapid control of pandemic H1N1 influenza by targeting NKT-cells

(2016) Bianca L. Artiaga et al.   Scientific Reports

Borrelia burgdorferi, the Causative Agent of Lyme Disease, Forms Drug-Tolerant Persister Cells

(2015) Bijaya Sharma et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Innate-like lymphocytes in intestinal infections

(2015) Michael S. Bennett et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Leishmania donovani skews the CD56+ Natural Killer T cell response during human visceral leishmaniasis

(2015) Sarita Kumari et al.   CYTOKINE

CD252 regulates mast cell mediated, CD1d-restricted NKT-cell activation in mice

(2015) Nestor Gonzalez Roldan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Pathogen-expanded CD11b+ invariant NKT cells feedback inhibit T cell proliferation via membrane-bound TGF-β1

(2015) Yanmei Han et al.   JOURNAL OF AUTOIMMUNITY

Human Invariant Natural Killer T cells possess immune-modulating functions duringAspergillusinfection

(2015) Antonia Beitzen-Heineke et al.   MEDICAL MYCOLOGY

Preserved Function of Circulating Invariant Natural Killer T Cells in Patients With Chronic Hepatitis B Virus Infection

(2015) Haoxiang Zhu et al.   MEDICINE

Antigen-specific human NKT cells from tuberculosis patients produce IL-21 to help B cells for the production of immunoglobulins

(2015) Changyou Wu et al.   Oncotarget

Type II NKT Cells in Inflammation, Autoimmunity, Microbial Immunity, and Cancer

(2015) Idania Marrero et al.   Frontiers in Immunology

Regulation of NKT Cell Localization in Homeostasis and Infection

(2015) Drew Slauenwhite et al.   Frontiers in Immunology

The Response of CD1d-Restricted Invariant NKT Cells to Microbial Pathogens and Their Products

(2015) Luc Van Kaer et al.   Frontiers in Immunology

Sphingolipids from a Symbiotic Microbe Regulate Homeostasis of Host Intestinal Natural Killer T Cells

(2014) Dingding An et al.   CELL

IFN-γ-producing NKT cells exacerbate sepsis by enhancing C5a generation via IL-10-mediated inhibition of CD55 expression on neutrophils

(2014) Ji Hyung Kim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mycobacterium Tuberculosis-Specific Memory NKT Cells in Patients with Tuberculous Pleurisy

(2014) Zitao Li et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Cutting Edge: Programmed Death-1/Programmed Death Ligand 1 Interaction Regulates the Induction and Maintenance of Invariant NKT Cell Anergy

(2014) W.-S. Chang et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Histamine Receptor H4 Activation Positively Regulates In Vivo IL-4 and IFN-  Production by Invariant NKT Cells

(2014) M. C. Leite-de-Moraes et al.   JOURNAL OF IMMUNOLOGY

Antigen-Dependent versus -Independent Activation of Invariant NKT Cells during Infection

(2014) K. L. Holzapfel et al.   JOURNAL OF IMMUNOLOGY

HIV infection: epidemiology, pathogenesis, treatment, and prevention

(2014) Gary Maartens et al.   LANCET

Surface expression of the hRSV nucleoprotein impairs immunological synapse formation with T cells

(2014) P. F. Cespedes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Invariant NKT Cell Response to Dengue Virus Infection in Human

(2014) Ponpan Matangkasombut et al.   PLoS Neglected Tropical Diseases

Immune Modulating Effects of NKT Cells in a Physiologically Low Dose Leishmania major Infection Model after αGalCer Analog PBS57 Stimulation

(2014) Klaus G. Griewank et al.   PLoS Neglected Tropical Diseases

iNKT Cell Production of GM-CSF Controls Mycobacterium tuberculosis

(2014) Alissa C. Rothchild et al.   PLoS Pathogens

The Intracellular Life of Cryptococcus neoformans

(2013) Carolina Coelho et al.   Annual Review of Pathology-Mechanisms of Disease

Dynamics of cellular immune responses in the acute phase of dengue virus infection

(2013) Tomoyuki Yoshida et al.   ARCHIVES OF VIROLOGY

Human metapneumovirus keeps dendritic cells from priming antigen-specific naive T cells

(2013) Pablo F. Céspedes et al.   IMMUNOLOGY

Exacerbation of Invasive Candida albicans Infection by Commensal Bacteria or a Glycolipid Through IFN-γ Produced in Part by iNKT Cells

(2013) Norihito Tarumoto et al.   JOURNAL OF INFECTIOUS DISEASES

PD-1/PDL1 and CD28/CD80 pathways modulate natural killer T cell function to inhibit hepatitis B virus replication

(2013) X. F. Wang et al.   JOURNAL OF VIRAL HEPATITIS

Malaria

(2013) Nicholas J White et al.   LANCET

Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells

(2013) You Jeong Lee et al.   NATURE IMMUNOLOGY

Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity

(2013) Lee A Albacker et al.   NATURE MEDICINE

Lack of PD-L1 Expression by iNKT Cells Improves the Course of Influenza A Infection

(2013) Hadi Maazi et al.   PLoS One

Production of α-Galactosylceramide by a Prominent Member of the Human Gut Microbiota

(2013) Laura C. Wieland Brown et al.   PLOS BIOLOGY

Development and function of murine ROR t+ iNKT cells are under TGF-  signaling control

(2012) C. Havenar-Daughton et al.   BLOOD

A Limited Role of iNKT Cells in Controlling Systemic Candida albicans Infections

(2012) Norihito Tarumoto et al.   JAPANESE JOURNAL OF INFECTIOUS DISEASES

Human and Mouse Type I Natural Killer T Cell Antigen Receptors Exhibit Different Fine Specificities for CD1d-Antigen Complex

(2012) Kwok S. Wun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Components of Streptococcus pneumoniae Suppress Allergic Airways Disease and NKT Cells by Inducing Regulatory T Cells

(2012) A. N. Thorburn et al.   JOURNAL OF IMMUNOLOGY

Key Role for Respiratory CD103+ Dendritic Cells, IFN- , and IL-17 in Protection Against Streptococcus pneumoniae Infection in Response to  -Galactosylceramide

(2012) S. Ivanov et al.   JOURNAL OF INFECTIOUS DISEASES

Immature murine NKT cells pass through a stage of developmentally programmed innate IL-4 secretion

(2012) Nina Dickgreber et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Lower TCR repertoire diversity in Traj18-deficient mice

(2012) Romain Bedel et al.   NATURE IMMUNOLOGY

Type II natural killer T cells use features of both innate-like and conventional T cells to recognize sulfatide self antigens

(2012) Enrico Girardi et al.   NATURE IMMUNOLOGY

Invariant NKT Cells Drive Hepatic Cytokinic Microenvironment Favoring Efficient Granuloma Formation and Early Control of Leishmania donovani Infection

(2012) Florence Robert-Gangneux et al.   PLoS One

Activation of Natural Killer Cells during Microbial Infections

(2012) Amir Horowitz et al.   Frontiers in Immunology

Does T Helper Differentiation Correlate with Resistance or Susceptibility to Infection with L. major? Some Insights From the Murine Model

(2012) Fabienne Tacchini-Cottier et al.   Frontiers in Immunology

Innate Recognition of Cell Wall β-Glucans Drives Invariant Natural Killer T Cell Responses against Fungi

(2011) Nadia R. Cohen et al.   Cell Host & Microbe

A Molecular Basis for NKT Cell Recognition of CD1d-Self-Antigen

(2011) Thierry Mallevaey et al.   IMMUNITY

Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria

(2011) Yuki Kinjo et al.   NATURE IMMUNOLOGY

Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses

(2011) Pheh-Ping Chang et al.   NATURE IMMUNOLOGY

Restored Circulating Invariant NKT Cells Are Associated with Viral Control in Patients with Chronic Hepatitis B

(2011) Xiaotao Jiang et al.   PLoS One

Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance

(2011) A. L. St. John et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

α-Galactosylceramide as a Therapeutic Agent for PulmonaryMycobacterium tuberculosisInfection

(2010) Isabel Sada-Ovalle et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inhibition of lipid antigen presentation in dendritic cells by HIV-1 Vpu interference with CD1d recycling from endosomal compartments

(2010) M. Moll et al.   BLOOD

Clinical development of a novel CD1d-binding NKT cell ligand as a vaccine adjuvant

(2010) Neal N. Padte et al.   CLINICAL IMMUNOLOGY

Cytokine dependent and independent iNKT cell activation

(2010) Emma C. Reilly et al.   CYTOKINE

Transcriptional control of invariant NKT cell development

(2010) Rupali Das et al.   IMMUNOLOGICAL REVIEWS

 -Galactosylceramide Promotes Killing of Listeria monocytogenes within the Macrophage Phagosome through Invariant NKT-Cell Activation

(2010) M. Emoto et al.   INFECTION AND IMMUNITY

Activation of pulmonary invariant NKT cells leads to exacerbation of acute lung injury caused by LPS through local production of IFN-  and TNF-  by Gr-1+ monocytes

(2010) T. Aoyagi et al.   INTERNATIONAL IMMUNOLOGY

Cutting Edge: Thymic NK Cells Develop Independently from T Cell Precursors

(2010) V. S. G. Ribeiro et al.   JOURNAL OF IMMUNOLOGY

CD1d-Restricted IFN- -Secreting NKT Cells Promote Immune Complex-Induced Acute Lung Injury by Regulating Macrophage-Inflammatory Protein-1  Production and Activation of Macrophages and Dendritic Cells

(2010) J. H. Kim et al.   JOURNAL OF IMMUNOLOGY

Invariant NKT Cells Preferentially Modulate the Function of CD8α + Dendritic Cell Subset in Inducing Type 1 Immunity against Infection

(2010) Antony George Joyee et al.   JOURNAL OF IMMUNOLOGY

α-Galactosylceramide Analogs with Weak Agonist Activity for Human iNKT Cells Define New Candidate Anti-Inflammatory Agents

(2010) Gabriel Bricard et al.   PLoS One

Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant

(2010) X. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

iNKT cell development is orchestrated by different branches of TGF-β signaling

(2009) Jean-Marc Doisne et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Local Production of IFN-  by Invariant NKT Cells Modulates Acute Lyme Carditis

(2009) C. M. Olson et al.   JOURNAL OF IMMUNOLOGY

Natural Killer T Cells: An Unconventional T-Cell Subset with Diverse Effector and Regulatory Functions

(2009) Anna Balato et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cellular Immune Responses to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection in Senescent BALB/c Mice: CD4+ T Cells Are Important in Control of SARS-CoV Infection

(2009) J. Chen et al.   JOURNAL OF VIROLOGY

Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease

(2009) J. BRIAN de SOUZA et al.   PARASITOLOGY

Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells

(2009) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity

(2009) C. Guillonneau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD1d-restricted iNKT cells, the ‘Swiss-Army knife’ of the immune system

(2008) Jennifer L Matsuda et al.   CURRENT OPINION IN IMMUNOLOGY

Activation of invariant NKT cells enhances the innate immune response and improves the disease course in influenza A virus infection

(2008) Ling‐Pei Ho et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The growing burden of antimicrobial resistance

(2008) P. M. Hawkey   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Invariant NKT cells reduce the immunosuppressive activity of influenza A virus–induced myeloid-derived suppressor cells in mice and humans

(2008) Carmela De Santo et al.   JOURNAL OF CLINICAL INVESTIGATION

NK T cells provide lipid antigen-specific cognate help for B cells

(2008) E. A. Leadbetter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo

(2008) P. Barral et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Invariant NKT Cells Recognize Mycobacterium tuberculosis–Infected Macrophages, Produce Interferon-γ, and Kill Intracellular Bacteria

(2008) Isabel Sada-Ovalle et al.   PLoS Pathogens

Immunological decision-making: how does the immune system decide to mount a helper T-cell response?

(2007) Gerard E. Kaiko et al.   IMMUNOLOGY