Key advances in biocatalytic phosphorylations in the last two decades: Biocatalytic syntheses in vitro and biotransformations in vivo (in humans)

Preparative‐Scale Enzymatic Synthesis of rac ‐Glycerol‐1‐phosphate from Crude Glycerol Using Acid Phosphatases and Phosphate

(2020) Gábor Tasnádi et al.   ChemSusChem

The shift of phosphorus transfers in global fisheries and aquaculture

(2020) Yuanyuan Huang et al.   Nature Communications

A Multi-Enzymatic Cascade Reaction for the Synthesis of Vidarabine 5′-Monophosphate

(2020) Marina Simona Robescu et al.   Catalysts

Catalytic Chemoselective O-Phosphorylation of Alcohols

(2020) K. Domon et al.   ACS Central Science

The Selectivity of Fosfosal for STAT5b over STAT5a is Mediated by Arg566 in the Linker Domain

(2020) Julian Gräb et al.   CHEMBIOCHEM

Evolving understanding of HIV-1 reverse transcriptase structure, function, inhibition, and resistance

(2020) Francesc Xavier RUIZ et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Antibiotics in the clinical pipeline in October 2019

(2020) Mark S. Butler et al.   JOURNAL OF ANTIBIOTICS

Supply of phosphate to early Earth by photogeochemistry after meteoritic weathering

(2020) Dougal J. Ritson et al.   Nature Geoscience

Let’s Make White Phosphorus Obsolete

(2020) Michael B. Geeson et al.   ACS Central Science

Synthesis of Islatravir Enabled by a Catalytic, Enantioselective Alkynylation of a Ketone

(2020) Niki R. Patel et al.   ORGANIC LETTERS

Phosphine gas in the cloud decks of Venus

(2020) Jane S. Greaves et al.   Nature Astronomy

Natural Products Containing ‘Rare’ Organophosphorus Functional Groups

(2019) Janusz Petkowski et al.   MOLECULES

Bioeconomy for sustainable development

(2019) Alfredo Aguilar et al.   Biotechnology Journal

Probing the substrate promiscuity of isopentenyl phosphate kinase as a platform for hemiterpene analogue production

(2019) Sean Lund et al.   CHEMBIOCHEM

Facile synthesis of D-xylulose-5-phosphate and L-xylulose-5-phosphate by xylulokinase-catalyzed phosphorylation

(2019) Norman Hardt et al.   BIOCATALYSIS AND BIOTRANSFORMATION

Efficient biocatalytic synthesis of D-tagatose 1,6-diphosphate by LacC-catalysed phosphorylation of D-tagatose 6-phosphate

(2019) Bernhard Schoenenberger et al.   BIOCATALYSIS AND BIOTRANSFORMATION

Enzyme-Catalyzed Kinetic Resolution of Chiral Precursors to Antiviral Prodrugs

(2019) Dao Feng Xiang et al.   BIOCHEMISTRY

Functional Characterization of YdjH, a Sugar Kinase of Unknown Specificity in Escherichia coli K12

(2019) Jamison P. Huddleston et al.   BIOCHEMISTRY

Fosmidomycin biosynthesis diverges from related phosphonate natural products

(2019) Elizabeth I. Parkinson et al.   Nature Chemical Biology

ATP regeneration system in chemoenzymatic amide bond formation with thermophilic CoA ligase

(2019) Anne Zaparucha et al.   ChemCatChem

Thermodynamics of Prebiotic Phosphorylation

(2019) Matthew A. Pasek   CHEMICAL REVIEWS

Human Deoxycytidine Kinase Is a Valuable Biocatalyst for the Synthesis of Nucleotide Analogues

(2019) Katja F. Hellendahl et al.   Catalysts

Characterization of alkaline phosphatase PhoK from Sphingomonas sp. BSAR-1 for phosphate monoester synthesis and hydrolysis

(2019) Michael Lukesch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

ALMA and ROSINA detections of phosphorus-bearing molecules: the interstellar thread between star-forming regions and comets

(2019) V M Rivilla et al.   MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

(2019) Mark A. Huffman et al.   SCIENCE

Characterization of a thermotolerant ROK-type mannofructokinase from Streptococcus mitis: application to the synthesis of phosphorylated sugars

(2018) Carine Vergne-Vaxelaire et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Recombinant AroL-Catalyzed Phosphorylation for the Efficient Synthesis of Shikimic Acid 3-Phosphate

(2018) Bernhard Schoenenberger et al.   Biotechnology Journal

Horizons of Systems Biocatalysis and Renaissance of Metabolite Synthesis

(2018) Roland Wohlgemuth   Biotechnology Journal

Characterisation of a Bacterial Galactokinase with High Activity and Broad Substrate Tolerance for Chemoenzymatic Synthesis of 6-Aminogalactose-1-Phosphate and Analogues

(2018) Kun Huang et al.   CHEMBIOCHEM

Phosphorylation Catalyzed by Dihydroxyacetone Kinase

(2018) Dominik Gauss et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

SbnI is a free serine kinase that generatesO-phospho-l-serine for staphyloferrin B biosynthesis inStaphylococcus aureus

(2018) Meghan M. Verstraete et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset

(2018) Charlotte M. Miton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombinant AroL-Catalyzed Phosphorylation for the Efficient Synthesis of Shikimic Acid 3-Phosphate

(2018) Bernhard Schoenenberger et al.   Biotechnology Journal

Horizons of Systems Biocatalysis and Renaissance of Metabolite Synthesis

(2018) Roland Wohlgemuth   Biotechnology Journal

Evaluation of Natural and Synthetic Phosphate Donors for the Improved Enzymatic Synthesis of Phosphate Monoesters

(2018) Gábor Tasnádi et al.   ADVANCED SYNTHESIS & CATALYSIS

Substrate Specificity and Chemical Mechanism for the Reaction Catalyzed by Glutamine Kinase

(2018) Zane W. Taylor et al.   BIOCHEMISTRY

The Role of the Phosphorus Atom in Drug Design

(2018) Juan Bautista Rodriguez et al.   ChemMedChem

A role for phosphorus redox in emerging and modern biochemistry

(2018) Matthew Pasek   CURRENT OPINION IN CHEMICAL BIOLOGY

Biosynthesis of an antiviral compound using a stabilized phosphopentomutase by multipoint covalent immobilization

(2017) Cintia W. Rivero et al.   JOURNAL OF BIOTECHNOLOGY

The ProTide Prodrug Technology: From the Concept to the Clinic

(2017) Youcef Mehellou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of a Glutamine Kinase Required for the Biosynthesis of the O-Methyl Phosphoramidate Modifications Found in the Capsular Polysaccharides of Campylobacter jejuni

(2017) Zane W. Taylor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biocatalytic Phosphorylations of Metabolites: Past, Present, and Future

(2017) Roland Wohlgemuth et al.   TRENDS IN BIOTECHNOLOGY

Bioreaction Engineering Leading to Efficient Synthesis of L-Glyceraldehyd-3-Phosphate

(2017) Getachew S. Molla et al.   Biotechnology Journal

New Synthetic Methods for Phosphate Labeling

(2017) Amit K. Dutta et al.   Topics in Current Chemistry

Amiselimod, a novel sphingosine 1-phosphate receptor-1 modulator, has potent therapeutic efficacy for autoimmune diseases, with low bradycardia risk

(2016) Kunio Sugahara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Phosphonate Biochemistry

(2016) Geoff P. Horsman et al.   CHEMICAL REVIEWS

The ProTides Boom

(2016) Youcef Mehellou   ChemMedChem

Approved Antiviral Drugs over the Past 50 Years

(2016) Erik De Clercq et al.   CLINICAL MICROBIOLOGY REVIEWS

Microbial transformations in phosphonate biosynthesis and catabolism, and their importance in nutrient cycling

(2016) Jason P Chin et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Biocatalytic functionalization of hydroxyalkyl acrylates and phenoxyethanol via phosphorylation

(2016) Gábor Tasnádi et al.   JOURNAL OF BIOTECHNOLOGY

Evolution of the global phosphorus cycle

(2016) Christopher T. Reinhard et al.   NATURE

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

(2016) Travis K. Warren et al.   NATURE

Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA)

(2016) Zhe Li Salie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An archaeal ADP-dependent serine kinase involved in cysteine biosynthesis and serine metabolism

(2016) Yuki Makino et al.   Nature Communications

Facile Enzymatic Synthesis of Phosphorylated Ketopentoses

(2016) Liuqing Wen et al.   ACS Catalysis

Straightforward Synthesis of Terminally Phosphorylated L -Sugars via Multienzymatic Cascade Reactions

(2015) Virgil Hélaine et al.   ADVANCED SYNTHESIS & CATALYSIS

Diastereoselective Synthesis of Glycosyl Phosphates by Using a Phosphorylase-Phosphatase Combination Catalyst

(2015) Patricia Wildberger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Facile Enzymatic Synthesis of Ketoses

(2015) Liuqing Wen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Facile enzymatic synthesis of sugar 1-phosphates as substrates for phosphorylases using anomeric kinases

(2015) Yuan Liu et al.   CARBOHYDRATE RESEARCH

Enzymatic synthesis using glycoside phosphorylases

(2015) Ellis C. O’Neill et al.   CARBOHYDRATE RESEARCH

Emerging Enzymes for ATP Regeneration in Biocatalytic Processes

(2015) Jennifer N. Andexer et al.   CHEMBIOCHEM

Exploiting Acid Phosphatases in the Synthesis of Phosphorylated Monoalcohols and Diols

(2015) Gábor Tasnádi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Greening the global phosphorus cycle: how green chemistry can help achieve planetary P sustainability

(2015) Paul J. A. Withers et al.   GREEN CHEMISTRY

Development of a Diastereoselective Phosphorylation of a Complex Nucleoside via Dynamic Kinetic Resolution

(2015) Kristy Tran et al.   JOURNAL OF ORGANIC CHEMISTRY

Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes

(2015) Kou-San Ju et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Planetary boundaries: Guiding human development on a changing planet

(2015) W. Steffen et al.   SCIENCE

ImmobilizedDrosophila melanogasterDeoxyribonucleoside Kinase (DmdNK) as a High Performing Biocatalyst for the Synthesis of Purine Arabinonucleotides

(2014) Immacolata Serra et al.   ADVANCED SYNTHESIS & CATALYSIS

Microbially Mediated Transformations of Phosphorus in the Sea: New Views of an Old Cycle

(2014) David M. Karl   Annual Review of Marine Science

Chemical and enzymatic methodologies for the synthesis of enantiomerically pure glyceraldehyde 3-phosphates

(2014) Dominik Gauss et al.   CARBOHYDRATE RESEARCH

Beyond C, H, O, and N! Analysis of the Elemental Composition of U.S. FDA Approved Drug Architectures

(2014) Brandon R. Smith et al.   JOURNAL OF MEDICINAL CHEMISTRY

Phosphate esters and anhydrides – recent strategies targeting nature's favoured modifications

(2014) Henning J. Jessen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Biocatalytic asymmetric phosphorylation of mevalonate

(2014) R. Matsumi et al.   RSC Advances

Phosphonate biosynthesis and catabolism: a treasure trove of unusual enzymology

(2013) Spencer C Peck et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Efficient biocatalytic processes for highly valuable terminally phosphorylated C5 to C9d-ketoses

(2013) C. Guérard-Hélaine et al.   GREEN CHEMISTRY

Why nature really chose phosphate

(2013) Shina C. L. Kamerlin et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Conferring the ability to utilize inorganic polyphosphate on ATP-specific NAD kinase

(2013) Yusuke Nakamichi et al.   Scientific Reports

One-Pot Cascade Reactions using Fructose-6-phosphate Aldolase: Efficient Synthesis of D-Arabinose 5-Phosphate, D-Fructose 6-Phosphate and Analogues

(2012) Israel Sánchez-Moreno et al.   ADVANCED SYNTHESIS & CATALYSIS

Continuous-Flow Reactor-Based Enzymatic Synthesis of Phosphorylated Compounds on a Large Scale

(2012) Lara Babich et al.   CHEMISTRY-A EUROPEAN JOURNAL

GFAJ-1 Is an Arsenate-Resistant, Phosphate-Dependent Organism

(2012) T. J. Erb et al.   SCIENCE

Plate Tectonics, the Wilson Cycle, and Mantle Plumes: Geodynamics from the Top

(2011) Kevin Burke   Annual Review of Earth and Planetary Sciences

Synthesis of non-natural carbohydrates from glycerol and aldehydes in a one-pot four-enzyme cascade reaction

(2011) Lara Babich et al.   GREEN CHEMISTRY

A broken biogeochemical cycle

(2011) James Elser et al.   NATURE

Operational stability of immobilized sucrose phosphorylase: Continuous production of α-glucose-1-phosphate at elevated temperatures

(2011) Karel De Winter et al.   PROCESS BIOCHEMISTRY

Peak Phosphorus: Clarifying the Key Issues of a Vigorous Debate about Long-Term Phosphorus Security

(2011) Dana Cordell et al.   Sustainability

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

(2010) Volker Brinkmann et al.   NATURE REVIEWS DRUG DISCOVERY

Improvement of an Acid Phosphatase/DHAP-Dependent Aldolase Cascade Reaction by Using Directed Evolution

(2009) Teunie van Herk et al.   CHEMBIOCHEM

Aryloxy Phosphoramidate Triesters: a Technology for Delivering Monophosphorylated Nucleosides and Sugars into Cells

(2009) Youcef Mehellou et al.   ChemMedChem