CCR5 tyrosine sulfation heterogeneity generates cell surface receptor subpopulations with different ligand binding properties

Maraviroc intensification modulates atherosclerotic progression in HIV suppressed patients at high cardiovascular risk. A randomized, cross-over, pilot study

(2019) Daniela Francisci et al.   Open Forum Infectious Diseases

CCR5 silencing reduces inflammatory response, inhibits viability, and promotes apoptosis of synovial cells in rat models of rheumatoid arthritis through the MAPK signaling pathway

(2019) You‐Yu Lan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cholesterol impacts chemokine CCR5 receptor ligand‐binding activity

(2019) Pierre Calmet et al.   FEBS Journal

CCR5: Established paradigms and new frontiers for a ‘celebrity’ chemokine receptor

(2018) Ilaria Scurci et al.   CYTOKINE

The solution structure of monomeric CCL5 in complex with a doubly sulfated N-terminal segment of CCR5

(2018) Meital Abayev et al.   FEBS Journal

Inhibition of the CCL5/CCR5 Axis against the Progression of Gastric Cancer

(2018) Donatella Aldinucci et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CCR5 adopts three homodimeric conformations that control cell surface delivery

(2018) Jun Jin et al.   Science Signaling

CCR5 adopts three homodimeric conformations that control cell surface delivery

(2018) Jun Jin et al.   Science Signaling

CCR5 antagonism by maraviroc inhibits Hodgkin lymphoma microenvironment interactions and xenograft growth

(2018) Naike Casagrande et al.   HAEMATOLOGICA

CCR5 structural plasticity shapes HIV-1 phenotypic properties

(2018) Philippe Colin et al.   PLoS Pathogens

Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV

(2017) Yi Zheng et al.   IMMUNITY

Systematic comparison of 2A peptides for cloning multi-genes in a polycistronic vector

(2017) Ziqing Liu et al.   Scientific Reports

Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients

(2016) Niels Halama et al.   CANCER CELL

A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors

(2016) Ryan J Park et al.   NATURE GENETICS

CCR5 blockade for neuroinflammatory diseases — beyond control of HIV

(2016) Guillaume Martin-Blondel et al.   Nature Reviews Neurology

Chemokine and chemokine receptor structure and interactions: implications for therapeutic strategies

(2015) Irina Kufareva et al.   IMMUNOLOGY AND CELL BIOLOGY

CCR5 susceptibility to ligand-mediated down-modulation differs between human T lymphocytes and myeloid cells

(2015) James M. Fox et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tyrosine Sulfation as a Protein Post-Translational Modification

(2015) Yuh-Shyong Yang et al.   MOLECULES

Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity

(2014) Jason W. Griffith et al.   Annual Review of Immunology

Targeting Spare CC Chemokine Receptor 5 (CCR5) as a Principle to Inhibit HIV-1 Entry

(2014) Jun Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CCR5 Conformations Are Dynamic and Modulated by Localization, Trafficking and G Protein Association

(2014) Ayanna J. Flegler et al.   PLoS One

The structural role of receptor tyrosine sulfation in chemokine recognition

(2013) Justin P Ludeman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Use of G-Protein-Coupled and -Uncoupled CCR5 Receptors by CCR5 Inhibitor-Resistant and -Sensitive Human Immunodeficiency Virus Type 1 Variants

(2013) R. Berro et al.   JOURNAL OF VIROLOGY

HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines

(2013) Philippe Colin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple CCR5 Conformations on the Cell Surface Are Used Differentially by Human Immunodeficiency Viruses Resistant or Sensitive to CCR5 Inhibitors

(2011) R. Berro et al.   JOURNAL OF VIROLOGY

Differential G-protein-coupled Receptor Phosphorylation Provides Evidence for a Signaling Bar Code

(2010) Adrian J. Butcher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CC Chemokine Receptor 5 (CCR5) Desensitization

(2010) Jean-Michel Escola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 - and  -cytoplasmic actins display distinct distribution and functional diversity

(2009) V. Dugina et al.   JOURNAL OF CELL SCIENCE

Phosphorylation Analysis of G Protein-Coupled Receptor by Mass Spectrometry: Identification of a Phosphorylation Site in V2 Vasopressin Receptor

(2008) Shilan Wu et al.   ANALYTICAL CHEMISTRY

Highly potent, fully recombinant anti-HIV chemokines: Reengineering a low-cost microbicide

(2008) H. Gaertner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA