标题
Mitochondrial stress and GDF15 in the pathophysiology of sepsis
作者
关键词
GDF15, Mitochondrial stress, Integrated stress response, Sepsis, Inflammation
出版物
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Volume 696, Issue -, Pages 108668
出版商
Elsevier BV
发表日期
2020-11-12
DOI
10.1016/j.abb.2020.108668
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury
- (2020) Jing Liu et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Mitochondrial stress is relayed to the cytosol by an OMA1–DELE1–HRI pathway
- (2020) Xiaoyan Guo et al. NATURE
- A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol
- (2020) Evelyn Fessler et al. NATURE
- Mitochondrial Functions in Infection and Immunity
- (2020) Varnesh Tiku et al. TRENDS IN CELL BIOLOGY
- Serine Catabolism Feeds NADH when Respiration Is Impaired
- (2020) Lifeng Yang et al. Cell Metabolism
- GDF15: A hormone conveying somatic distress to the brain
- (2020) Samuel M Lockhart et al. ENDOCRINE REVIEWS
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
- CXCL5-mediated recruitment of neutrophils into the peritoneal cavity of Gdf15-deficient mice protects against abdominal sepsis
- (2020) Isa Santos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pivotal role of the transcriptional co-activator YAP in trophoblast stemness of the developing human placenta
- (2020) Gudrun Meinhardt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell
- (2020) Eran Mick et al. eLife
- HSF1 is required for induction of mitochondrial chaperones during the mitochondrial unfolded protein response
- (2020) Arpit Katiyar et al. FEBS Open Bio
- Growth differentiation factor 15 protects against the aging‐mediated systemic inflammatory response in humans and mice
- (2020) Ji Sun Moon et al. AGING CELL
- Antibody-mediated inhibition of GDF15–GFRAL activity reverses cancer cachexia in mice
- (2020) Rowena Suriben et al. NATURE MEDICINE
- The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic
- (2020) Leiluo Geng et al. Nature Reviews Endocrinology
- GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans
- (2019) Satish Patel et al. Cell Metabolism
- Specificity, versatility, and control of TGF-β family signaling
- (2019) Rik Derynck et al. Science Signaling
- The motor protein Myo1c regulates transforming growth factor-β-signaling and fibrosis in podocytes
- (2019) Ehtesham Arif et al. KIDNEY INTERNATIONAL
- GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS
- (2019) Vicky Wang-Wei Tsai et al. INTERNATIONAL JOURNAL OF OBESITY
- Cardioprotection by the mitochondrial unfolded protein response requires ATF5
- (2019) Yves T. Wang et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Mitochondrial bioenergetics links inflammation and cardiac contractility in endotoxemia
- (2019) Tamara Antonela Vico et al. BASIC RESEARCH IN CARDIOLOGY
- Heme-regulated eIF2alpha kinase in erythropoiesis and hemoglobinopthies
- (2019) Jane-Jane Chen et al. BLOOD
- GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance
- (2019) Harding H. Luan et al. CELL
- Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions
- (2019) Saara Forsström et al. Cell Metabolism
- MIC-1/GDF15 Overexpression Is Associated with Increased Functional Recovery in Traumatic Spinal Cord Injury
- (2019) Masoud Hassanpour Golakani et al. JOURNAL OF NEUROTRAUMA
- GDF15 mediates the effects of metformin on body weight and energy balance
- (2019) Anthony P. Coll et al. NATURE
- Undulating changes in human plasma proteome profiles across the lifespan
- (2019) Benoit Lehallier et al. NATURE MEDICINE
- Plasma proteomic signature of age in healthy humans
- (2018) Toshiko Tanaka et al. AGING CELL
- Hepatic GDF15 is regulated by CHOP of the unfolded protein response and alleviates NAFLD progression in obese mice
- (2018) Ding Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- HCV-induced EGFR-ERK signaling promotes a pro-inflammatory and pro-angiogenic signature contributing to liver cancer pathogenesis
- (2018) Mohammed Benkheil et al. BIOCHEMICAL PHARMACOLOGY
- YAP promotes breast cancer metastasis by repressing growth differentiation factor-15
- (2018) Ting Wang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Human Aging and Longevity Are Characterized by High Levels of Mitokines
- (2018) Maria Conte et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Sepsis and septic shock
- (2018) Maurizio Cecconi et al. LANCET
- Mitochondrial dynamics in adaptive and maladaptive cellular stress responses
- (2018) Verónica Eisner et al. NATURE CELL BIOLOGY
- C5a induces A549 cell proliferation of non-small cell lung cancer via GDF15 gene activation mediated by GCN5-dependent KLF5 acetylation
- (2018) Chenhui Zhao et al. ONCOGENE
- The MIC-1/GDF15-GFRAL Pathway in Energy Homeostasis: Implications for Obesity, Cachexia, and Other Associated Diseases
- (2018) Vicky W.W. Tsai et al. Cell Metabolism
- GDF15 maturation requires proteolytic cleavage by PCSK3, 5 and 6
- (2018) Jing Jing Li et al. MOLECULAR AND CELLULAR BIOLOGY
- Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals
- (2017) Pedro M. Quirós et al. JOURNAL OF CELL BIOLOGY
- NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development
- (2017) Nivedita M. Ratnam et al. JOURNAL OF CLINICAL INVESTIGATION
- Growth Differentiation Factor–15 and Risk of CKD Progression
- (2017) Viji Nair et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15
- (2017) Jer-Yuan Hsu et al. NATURE
- GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand
- (2017) Linda Yang et al. NATURE MEDICINE
- GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates
- (2017) Shannon E Mullican et al. NATURE MEDICINE
- The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL
- (2017) Paul J Emmerson et al. NATURE MEDICINE
- The mitochondrial UPR: mechanisms, physiological functions and implications in ageing
- (2017) Tomer Shpilka et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Sex-specific differences in the modulation of Growth Differentiation Factor 15 (GDF15) by hyperoxia in vivo and in vitro : Role of Hif-1α
- (2017) Yuhao Zhang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells
- (2017) Inge M.N. Wortel et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Growth Differentiation Factor-15 Deficiency Augments Inflammatory Response and Exacerbates Septic Heart and Renal Injury Induced by Lipopolysaccharide
- (2017) Palida Abulizi et al. Scientific Reports
- GDF15 deficiency exacerbates chronic alcohol- and carbon tetrachloride-induced liver injury
- (2017) Hyo Kyun Chung et al. Scientific Reports
- The Transcription Factor ATF5 Mediates a Mammalian Mitochondrial UPR
- (2016) Christopher J. Fiorese et al. CURRENT BIOLOGY
- Secreted growth differentiation factor 15 as a potential biomarker for mitochondrial dysfunctions in aging and age-related disorders
- (2016) Yasunori Fujita et al. Geriatrics & Gerontology International
- Macrophages in Tissue Repair, Regeneration, and Fibrosis
- (2016) Thomas A. Wynn et al. IMMUNITY
- The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
- (2016) Mervyn Singer et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis
- (2016) Hyo Kyun Chung et al. JOURNAL OF CELL BIOLOGY
- Mitonuclear communication in homeostasis and stress
- (2016) Pedro M. Quirós et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mitochondrial Function in Sepsis
- (2016) Nishkantha Arulkumaran et al. SHOCK
- Mitochondrial diseases
- (2016) Gráinne S. Gorman et al. Nature Reviews Disease Primers
- Growth differentiation factor 15 as a useful biomarker for mitochondrial disorders
- (2015) Shuichi Yatsuga et al. ANNALS OF NEUROLOGY
- Sepsis: a roadmap for future research
- (2015) Jonathan Cohen et al. LANCET INFECTIOUS DISEASES
- GDF15 is a novel biomarker to evaluate efficacy of pyruvate therapy for mitochondrial diseases
- (2015) Yasunori Fujita et al. MITOCHONDRION
- NAG-1/GDF15 accumulates in the nucleus and modulates transcriptional regulation of the Smad pathway
- (2015) K-W Min et al. ONCOGENE
- Transcriptomic profiling of TK2 deficient human skeletal muscle suggests a role for the p53 signalling pathway and identifies growth and differentiation factor-15 as a potential novel biomarker for mitochondrial myopathies
- (2014) Susana Kalko et al. BMC GENOMICS
- Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1-dependent mitochondrial dynamics
- (2014) M. J. Baker et al. EMBO JOURNAL
- Cardiac mitochondrial biogenesis in endotoxemia is not accompanied by mitochondrial function recovery
- (2014) Virginia Vanasco et al. FREE RADICAL BIOLOGY AND MEDICINE
- NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism
- (2014) K Chrysovergis et al. INTERNATIONAL JOURNAL OF OBESITY
- Maturation of Growth Differentiation Factor 15 in Human Placental Trophoblast Cells Depends on the Interaction With Matrix Metalloproteinase-26
- (2014) Sisi Li et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Early septic shock induces loss of oxidative phosphorylation yield plasticity in liver mitochondria
- (2014) Pierre Eyenga et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- An atlas of active enhancers across human cell types and tissues
- (2014) Robin Andersson et al. NATURE
- A promoter-level mammalian expression atlas
- (2014) NATURE
- Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP+
- (2014) A K Krug et al. Cell Death & Disease
- Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine
- (2013) Susanne Keipert et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Metformin-induced inhibition of the mitochondrial respiratory chain increases FGF21 expression via ATF4 activation
- (2013) Kook Hwan Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Regulation and effects of GDF-15 in the retina following optic nerve crush
- (2013) Petar Charalambous et al. CELL AND TISSUE RESEARCH
- Change in Growth Differentiation Factor 15 Concentrations over Time Independently Predicts Mortality in Community-Dwelling Elderly Individuals
- (2013) K. M. Eggers et al. CLINICAL CHEMISTRY
- TGF-b Superfamily Cytokine MIC-1/GDF15 Is a Physiological Appetite and Body Weight Regulator
- (2013) Vicky Wang-Wei Tsai et al. PLoS One
- Growth Differentiation Factor-15 Suppresses Maturation and Function of Dendritic Cells and Inhibits Tumor-Specific Immune Response
- (2013) Zhizhong Zhou et al. PLoS One
- Metabolomic profiling rationalized pyruvate efficacy in cybrid cells harboring MELAS mitochondrial DNA mutations
- (2012) Kenjiro Kami et al. MITOCHONDRION
- Macrophage Inhibitory Cytokine 1 (MIC-1/GDF15) Decreases Food Intake, Body Weight and Improves Glucose Tolerance in Mice on Normal & Obesogenic Diets
- (2012) Laurence Macia et al. PLoS One
- Growth-Differentiation Factor-15 Is a Robust, Independent Predictor of 11-Year Mortality Risk in Community-Dwelling Older Adults
- (2011) Lori B. Daniels et al. CIRCULATION
- Induction of dsRNA-activated protein kinase links mitochondrial unfolded protein response to the pathogenesis of intestinal inflammation
- (2011) Eva Rath et al. GUT
- Estrogen receptor mediates a distinct mitochondrial unfolded protein response
- (2011) L. Papa et al. JOURNAL OF CELL SCIENCE
- The Effects of Sepsis on Mitochondria
- (2011) Glòria Garrabou et al. JOURNAL OF INFECTIOUS DISEASES
- FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study
- (2011) Anu Suomalainen et al. LANCET NEUROLOGY
- GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice
- (2011) Tibor Kempf et al. NATURE MEDICINE
- Growth Differentiation Factor 15 Is Induced by Hepatitis C Virus Infection and Regulates Hepatocellular Carcinoma-Related Genes
- (2011) Youhui Si et al. PLoS One
- Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality
- (2010) Fredrik E. Wiklund et al. AGING CELL
- NSAID-activated gene-1 as a molecular target for capsaicin-induced apoptosis through a novel molecular mechanism involving GSK3 , C/EBP and ATF3
- (2010) S. H. Lee et al. CARCINOGENESIS
- GDF-15 Contributes to Proliferation and Immune Escape of Malignant Gliomas
- (2010) P. Roth et al. CLINICAL CANCER RESEARCH
- Growth/differentiation factor-15 is an abundant cytokine in human seminal plasma
- (2010) K. Soucek et al. HUMAN REPRODUCTION
- The TGF-β Superfamily Cytokine MIC-1/GDF15: Secretory Mechanisms Facilitate Creation of Latent Stromal Stores
- (2010) Asne R. Bauskin et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Inhibition of mitochondrial function induces an integrated stress response in oligodendroglia
- (2009) Jillian M. Silva et al. NEUROBIOLOGY OF DISEASE
- Nonsteroidal Anti-inflammatory Drug-activated Gene (NAG-1/GDF15) Expression Is Increased by the Histone Deacetylase Inhibitor Trichostatin A
- (2008) Hiroki Yoshioka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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