Myocardial infarction affects Cx43 content of extracellular vesicles secreted by cardiomyocytes

Matrix mechanics and water permeation regulate extracellular vesicle transport

(2020) Stephen Lenzini et al.   Nature Nanotechnology

EHD1 Modulates Cx43 Gap Junction Remodeling Associated With Cardiac Diseases

(2020) Tania Martins-Marques et al.   CIRCULATION RESEARCH

Biological Functions of Connexin43 Beyond Intercellular Communication

(2019) Tania Martins-Marques et al.   TRENDS IN CELL BIOLOGY

Biofabrication of Cell-Derived Nanovesicles: A Potential Alternative to Extracellular Vesicles for Regenerative Medicine

(2019) Nazma F. Ilahibaks et al.   Cells

Intra-Cardiac Release of Extracellular Vesicles Shapes Inflammation Following Myocardial InfarctionNovelty and Significance

(2018) Xavier Loyer et al.   CIRCULATION RESEARCH

The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43

(2018) Jian Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular interactions at the surface of extracellular vesicles

(2018) Edit I. Buzás et al.   Seminars in Immunopathology

Vesicle-Mediated Control of Cell Function: The Role of Extracellular Matrix and Microenvironment

(2018) Gorjana Rackov et al.   Frontiers in Physiology

Fourth universal definition of myocardial infarction (2018)

(2018) Kristian Thygesen et al.   EUROPEAN HEART JOURNAL

The interplay between exosomes and autophagy – partners in crime

(2018) Jing Xu et al.   JOURNAL OF CELL SCIENCE

Ischaemia alters the effects of cardiomyocyte-derived extracellular vesicles on macrophage activation

(2018) Rafael Almeida Paiva et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Role of connexin 43 in different forms of intercellular communication – gap junctions, extracellular vesicles and tunnelling nanotubes

(2017) Teresa M. Ribeiro-Rodrigues et al.   JOURNAL OF CELL SCIENCE

Three-dimensional scaffolds of fetal decellularized hearts exhibit enhanced potential to support cardiac cells in comparison to the adult

(2016) A.C. Silva et al.   BIOMATERIALS

Bin1 and CD2AP polarise the endocytic generation of beta‐amyloid

(2016) Florent Ubelmann et al.   EMBO REPORTS

Phosphate induces formation of matrix vesicles during odontoblast-initiated mineralization in vitro

(2016) Sandeep C. Chaudhary et al.   MATRIX BIOLOGY

Deubiquitylation of Protein Cargo Is Not an Essential Step in Exosome Formation

(2016) Alyssa R. Huebner et al.   MOLECULAR & CELLULAR PROTEOMICS

Circulating Extracellular Vesicles Contain miRNAs and are Released as Early Biomarkers for Cardiac Injury

(2016) Janine C. Deddens et al.   Journal of Cardiovascular Translational Research

Exosomes from Cardiomyocyte Progenitor Cells and Mesenchymal Stem Cells Stimulate Angiogenesis Via EMMPRIN

(2016) Krijn R. Vrijsen et al.   Advanced Healthcare Materials

Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes

(2015) Tania Martins-Marques et al.   BIOCHEMICAL JOURNAL

To beat or not to beat: degradation of Cx43 imposes the heart rhythm: Figure 1

(2015) Tânia Martins-Marques et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Targeting soluble proteins to exosomes using a ubiquitin tag

(2015) Yong Cheng et al.   BIOTECHNOLOGY AND BIOENGINEERING

Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart

(2015) Tania Martins-Marques et al.   MOLECULAR & CELLULAR PROTEOMICS

Glucose Starvation in Cardiomyocytes Enhances Exosome Secretion and Promotes Angiogenesis in Endothelial Cells

(2015) Nahuel A. Garcia et al.   PLoS One

Decellularization of Fibroblast Cell Sheets for Natural Extracellular Matrix Scaffold Preparation

(2015) Qi Xing et al.   TISSUE ENGINEERING PART C-METHODS

Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells

(2015) Ana Rosa Soares et al.   Scientific Reports

AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions

(2014) Teresa M. Ribeiro-Rodrigues et al.   FASEB JOURNAL

Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

(2014) Claudia Bang et al.   JOURNAL OF CLINICAL INVESTIGATION

Characterisation of Connexin Expression and Electrophysiological Properties in Stable Clones of the HL-1 Myocyte Cell Line

(2014) Priyanthi Dias et al.   PLoS One

Peptide and small molecule inhibitors of HECT-type ubiquitin ligases

(2014) Thomas Mund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A 14-3-3 Mode-1 Binding Motif Initiates Gap Junction Internalization During Acute Cardiac Ischemia

(2014) James W. Smyth et al.   TRAFFIC

Functional analysis and regulation of purified connexin hemichannels

(2014) Mariana C. Fiori et al.   Frontiers in Physiology

STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy

(2013) João Vasco Ferreira et al.   Autophagy

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles

(2013) Marina Colombo et al.   JOURNAL OF CELL SCIENCE

Two tyrosine-based sorting signals in the Cx43 C-terminus cooperate to mediate gap junction endocytosis

(2013) John T. Fong et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner

(2012) Eloy Bejarano et al.   MOLECULAR BIOLOGY OF THE CELL

Ubiquitin-mediated internalization of connexin43 is independent of the canonical endocytic tyrosine-sorting signal

(2011) Steve Catarino et al.   BIOCHEMICAL JOURNAL

The Tetraspanin CD63 Regulates ESCRT-Independent and -Dependent Endosomal Sorting during Melanogenesis

(2011) Guillaume van Niel et al.   DEVELOPMENTAL CELL

Eps15 interacts with ubiquitinated Cx43 and mediates its internalization

(2009) Henrique Girão et al.   EXPERIMENTAL CELL RESEARCH

The Use of Inhibitors to Study Endocytic Pathways of Gene Carriers: Optimization and Pitfalls

(2009) Dries Vercauteren et al.   MOLECULAR THERAPY