SUMOylation of PUM2 promotes the vasculogenic mimicry of glioma cells via regulating CEBPD

SUMO pathway inhibition targets an aggressive pancreatic cancer subtype

(2020) Alexander Biederstädt et al.   GUT

SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes

(2020) Yongxing Zhang et al.   Cell Reports

SUMOylation in the control of cholesterol homeostasis

(2020) Ana Talamillo et al.   Open Biology

Desmoglein-2 modulates tumor progression and osimertinib drug resistance through the EGFR/Src/PAK1 pathway in lung adenocarcinoma

(2020) Runsen Jin et al.   CANCER LETTERS

SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock

(2019) Frauke Liebelt et al.   Cell Reports

Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b

(2019) Kaibo Lin et al.   Cell Reports

Circ_0075932 in adipocyte-derived exosomes induces inflammation and apoptosis in human dermal keratinocytes by directly binding with PUM2 and promoting PUM2-mediated activation of AuroraA/NF-κB pathway

(2019) Xi Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A conserved role for transcription factor sumoylation in binding-site selection

(2019) Emanuel Rosonina   CURRENT GENETICS

CCAAT/enhancer binding protein delta (C/EBPδ) demonstrates a dichotomous role in tumour initiation and promotion of epithelial carcinoma

(2019) Ramlogan Sowamber et al.   EBioMedicine

RNA binding protein PUM2 promotes the stemness of breast cancer cells via competitively binding to neuropilin-1 (NRP-1) mRNA with miR-376a

(2019) Lansheng Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation

(2019) Shao-Ming Wang et al.   Journal of Neuroinflammation

Anti-angiogenesis triggers exosomes release from endothelial cells to promote tumor vasculogenesis

(2019) Ye Zeng et al.   Journal of Extracellular Vesicles

Hepatoma-derived growth factor supports the antiapoptosis and profibrosis of pancreatic stellate cells

(2019) Yi-Ting Chen et al.   CANCER LETTERS

Vasculogenic Mimicry: Become an Endothelial Cell “But Not So Much”

(2019) Mónica Fernández-Cortés et al.   Frontiers in Oncology

Dominant-Negative ATF5 Compromises Cancer Cell Survival by Targeting CEBPB and CEBPD

(2019) Xiaotian Sun et al.   MOLECULAR CANCER RESEARCH

The poly-SUMO2/3 protease SENP6 enables assembly of the constitutive centromere-associated network by group deSUMOylation

(2019) Frauke Liebelt et al.   Nature Communications

Investigation of the Prognostic Significance of Vasculogenic Mimicry and Its Inhibition by Sorafenib in Canine Mammary Gland Tumors

(2019) Maria Carolina Mangini Prado et al.   Frontiers in Oncology

Mitochondrial Retrograde Signaling in Mammals Is Mediated by the Transcriptional Cofactor GPS2 via Direct Mitochondria-to-Nucleus Translocation

(2018) Maria Dafne Cardamone et al.   MOLECULAR CELL

Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation

(2018) Shao-Ming Wang et al.   Redox Biology

RNA-binding protein PUM2 suppresses osteosarcoma progression via partly and competitively binding to STARD13 3′UTR with miRNAs

(2018) Ruixi Hu et al.   CELL PROLIFERATION

SUMO-Mediated Regulation of Nuclear Functions and Signaling Processes

(2018) Xiaolan Zhao   MOLECULAR CELL

Action and clinical significance of CCAAT/enhancer-binding protein delta in hepatocellular carcinoma

(2018) Pengyu Liu et al.   CARCINOGENESIS

The long noncoding RNA LINC00312 induces lung adenocarcinoma migration and vasculogenic mimicry through directly binding YBX1

(2018) Zhenzi Peng et al.   Molecular Cancer

Post-transcriptional Regulatory Functions of Mammalian Pumilio Proteins

(2018) Aaron C. Goldstrohm et al.   TRENDS IN GENETICS

Desmoglein 2 modulates extracellular vesicle release from squamous cell carcinoma keratinocytes

(2017) Andrew M. Overmiller et al.   FASEB JOURNAL

RNA interference for glioblastoma therapy: Innovation ladder from the bench to clinical trials

(2017) Eunice L. Lozada-Delgado et al.   LIFE SCIENCES

SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis

(2017) Haihua Yuan et al.   Molecular Cancer

SUMO proteases as potential targets for cancer therapy

(2017) Piotr Bialik et al.   Postepy Higieny I Medycyny Doswiadczalnej

History and current state of immunotherapy in glioma and brain metastasis

(2017) Tresa McGranahan et al.   Therapeutic Advances in Medical Oncology

Compositional Control of Phase-Separated Cellular Bodies

(2016) Salman F. Banani et al.   CELL

Inhibition of the EGFR/STAT3/CEBPD Axis Reverses Cisplatin Cross-resistance with Paclitaxel in the Urothelial Carcinoma of the Urinary Bladder

(2016) Wei-Jan Wang et al.   CLINICAL CANCER RESEARCH

Desmoglein-2 is overexpressed in non-small cell lung cancer tissues and its knockdown suppresses NSCLC growth by regulation of p27 and CDK2

(2016) Feng Cai et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

The C/EBPδ protein is stabilized by estrogen receptor α activity, inhibits SNAI2 expression and associates with good prognosis in breast cancer

(2016) D Mendoza-Villanueva et al.   ONCOGENE

NORAD: Defender of the Genome

(2016) Andrea Ventura   TRENDS IN GENETICS

Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome

(2016) Lih Yin Tan et al.   Oncotarget

c-Src/Cav1-dependent activation of the EGFR by Dsg2

(2016) Andrew M. Overmiller et al.   Oncotarget

HMDB and 5-AzadC Combination Reverses Tumor Suppressor CCAAT/Enhancer-Binding Protein Delta to Strengthen the Death of Liver Cancer Cells

(2015) C.-F. Li et al.   MOLECULAR CANCER THERAPEUTICS

SUMOylation-Mediated Regulation of Cell Cycle Progression and Cancer

(2015) Karolin Eifler et al.   TRENDS IN BIOCHEMICAL SCIENCES

Increase of Zinc Finger Protein 179 in Response to CCAAT/Enhancer Binding Protein Delta Conferring an Antiapoptotic Effect in Astrocytes of Alzheimer’s Disease

(2014) Shao-Ming Wang et al.   MOLECULAR NEUROBIOLOGY

SUMO1 modification stabilizes CDK6 protein and drives the cell cycle and glioblastoma progression

(2014) Anita C. Bellail et al.   Nature Communications

Control of Nuclear Activities by Substrate-Selective and Protein-Group SUMOylation

(2013) Stefan Jentsch et al.   Annual Review of Genetics

The Many Faces of C/EBPδ and their Relevance for Inflammation and Cancer

(2013) Kuppusamy Balamurugan et al.   International Journal of Biological Sciences

Glycogen synthase kinase-3β–mediated CCAAT/enhancer-binding protein delta phosphorylation in astrocytes promot es migration and activation of microglia/macrophages

(2013) Chiung-Yuan Ko et al.   NEUROBIOLOGY OF AGING

Loss of the desmosomal cadherin desmoglein-2 suppresses colon cancer cell proliferation through EGFR signaling

(2013) R Kamekura et al.   ONCOGENE

Vasculogenic mimicry: a novel target for glioma therapy

(2013) Yin-Sheng Chen et al.   Chinese Journal of Cancer

Tumor angiogenesis and anti-angiogenic therapy in malignant gliomas revisited

(2012) Karl H. Plate et al.   ACTA NEUROPATHOLOGICA

Molecular Pathways: Vasculogenic Mimicry in Tumor Cells: Diagnostic and Therapeutic Implications

(2012) D. A. Kirschmann et al.   CLINICAL CANCER RESEARCH

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY