标题
Paradoxical Roles of the MAL/Tirap Adaptor in Pathologies
作者
关键词
-
出版物
Frontiers in Immunology
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-09-25
DOI
10.3389/fimmu.2020.569127
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A peptide derived from the core β-sheet region of TIRAP decoys TLR4 and reduces inflammatory and autoimmune symptoms in murine models
- (2020) Asma Achek et al. EBioMedicine
- The αC helix of TIRAP holds therapeutic potential in TLR-mediated autoimmune diseases
- (2020) Masaud Shah et al. BIOMATERIALS
- The receptor for advanced glycation end-products (RAGE) is an important pattern recognition receptor (PRR) for inflammaging
- (2019) Thibault Teissier et al. BIOGERONTOLOGY
- Inhibition of the TIRAP-c-Jun interaction as a therapeutic strategy for AP1-mediated inflammatory responses
- (2019) Mansi Srivastava et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Phycocyanin Exerts Anti-Proliferative Effects through Down-Regulating TIRAP/NF-κB Activity in Human Non-Small Cell Lung Cancer Cells
- (2019) Shuai Hao et al. Cells
- Systemic RAGE ligands are upregulated in tuberculosis individuals with diabetes co-morbidity and modulated by anti-tuberculosis treatment and metformin therapy
- (2019) Nathella Pavan Kumar et al. BMC INFECTIOUS DISEASES
- HSV-1/TLR9-Mediated IFNβ and TNFα Induction Is Mal-Dependent in Macrophages
- (2019) Joanna Zyzak et al. Journal of Innate Immunity
- Growth ofMycobacterium tuberculosisin vivo segregates with host macrophage metabolism and ontogeny
- (2018) Lu Huang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes
- (2018) Bjoern Chapuy et al. NATURE MEDICINE
- Insight into Phosphatidylinositol-Dependent Membrane Localization of the Innate Immune Adaptor Protein Toll/Interleukin 1 Receptor Domain-Containing Adaptor Protein
- (2018) Mahesh Chandra Patra et al. Frontiers in Immunology
- Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination
- (2018) Sara B. Cohen et al. Cell Host & Microbe
- Carp Toll-like receptor 8 (Tlr8): An intracellular Tlr that recruits TIRAP as adaptor and activates AP-1 pathway in immune response
- (2018) Shijuan Shan et al. FISH & SHELLFISH IMMUNOLOGY
- Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein 180L Single-Nucleotide Polymorphism Is Associated With Susceptibility to Recurrent Pneumococcal Lower Respiratory Tract Infections in Children
- (2018) Johan N. Siebert et al. Frontiers in Immunology
- TIRAP p.R81C is a novel lymphoma risk variant which enhances cell proliferation via NF-κB mediated signaling in B-cells
- (2018) Regula Burkhard et al. HAEMATOLOGICA
- Cytoplasmic Linker Protein CLIP170 Negatively Regulates TLR4 Signaling by Targeting the TLR Adaptor Protein TIRAP
- (2017) Padmaja Jakka et al. JOURNAL OF IMMUNOLOGY
- Protein kinase C-delta (PKCδ), a marker of inflammation and tuberculosis disease progression in humans, is important for optimal macrophage killing effector functions and survival in mice
- (2017) S P Parihar et al. Mucosal Immunology
- Host-directed therapies for bacterial and viral infections
- (2017) Stefan H. E. Kaufmann et al. NATURE REVIEWS DRUG DISCOVERY
- Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling
- (2017) Mark M. Hughes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Membrane targeting of TIRAP is negatively regulated by phosphorylation in its phosphoinositide-binding motif
- (2017) Xiaolin Zhao et al. Scientific Reports
- Brucella TIR-like protein TcpB/Btp1 specifically targets the host adaptor protein MAL/TIRAP to promote infection
- (2016) Wenna Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Toll-Interleukin 1 Receptor domain-containing adaptor protein positively regulates BV2 cell M1 polarization
- (2016) Leilei Gong et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Epistatic interaction betweenMyD88andTIRAPagainstHelicobacter pylori
- (2016) Andrea Fulgione et al. FEBS LETTERS
- A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling
- (2016) Clíona Ní Cheallaigh et al. IMMUNITY
- Heterozygous mutants of TIRAP (S180L) polymorphism protect adult patients with Plasmodium falciparum infection against severe disease and mortality
- (2016) Aditya K. Panda et al. INFECTION GENETICS AND EVOLUTION
- MyD88 Adapter-like (Mal)/TIRAP Is Required for Cytokine Production by Splenic Ly6CloTLR2hibut Not by Ly6ChiTLR2hiMonocytes duringTrypanosoma cruziInfection
- (2016) Humberto Doriguêtto Gravina et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HMGB1/RAGE Signaling and Pro-Inflammatory Cytokine Responses in Non-HIV Adults with Active Pulmonary Tuberculosis
- (2016) Grace Lui et al. PLoS One
- Innate Immune Pattern Recognition: A Cell Biological Perspective
- (2015) Sky W. Brubaker et al. Annual Review of Immunology
- Role of S180L polymorphism in etiology of malaria caused by Plasmodium falciparum in a small group of Pakistani population
- (2015) Syed Kashif Nawaz et al. Bosnian Journal of Basic Medical Sciences
- A Single Bacterial Immune Evasion Strategy Dismantles Both MyD88 and TRIF Signaling Pathways Downstream of TLR4
- (2015) Charles V. Rosadini et al. Cell Host & Microbe
- Microbial strategies for antagonizing Toll-like-receptor signal transduction
- (2015) Charles V Rosadini et al. CURRENT OPINION IN IMMUNOLOGY
- MyD88 adaptor-like (Mal) regulates intestinal homeostasis and colitis-associated colorectal cancer in mice
- (2014) Gabriella Aviello et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- A Promiscuous Lipid-Binding Protein Diversifies the Subcellular Sites of Toll-like Receptor Signal Transduction
- (2014) Kevin S. Bonham et al. CELL
- Genetic polymorphisms in the Toll-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer
- (2014) Natalia Castaño-Rodríguez et al. HUMAN IMMUNOLOGY
- TIRAP C539T polymorphism contributes to tuberculosis susceptibility: Evidence from a meta-analysis
- (2014) Qianqian Liu et al. INFECTION GENETICS AND EVOLUTION
- Association of TLR4 (D299G, T399I), TLR9 −1486T>C, TIRAP S180L and TNF-α promoter (−1031, −863, −857) polymorphisms with risk for systemic lupus erythematosus among South Indians
- (2014) Y Rupasree et al. LUPUS
- A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis
- (2014) N J Bernard et al. Mucosal Immunology
- The MyD88 rs6853 and TIRAP rs8177374 polymorphic sites are associated with resistance to human pulmonary tuberculosis
- (2013) R Capparelli et al. GENES AND IMMUNITY
- Mal, more than a bridge to MyD88
- (2013) Nicholas J. Bernard et al. IUBMB LIFE
- MyD88 adaptor-like (Mal) functions in the epithelial barrier and contributes to intestinal integrity via protein kinase C
- (2013) S C Corr et al. Mucosal Immunology
- BtpB, a novel Brucella TIR-containing effector protein with immune modulatory functions
- (2013) Suzana P. Salcedo et al. Frontiers in Cellular and Infection Microbiology
- Association of Mal/TIRAP S180L variant polymorphism with decreased infection risk in patients with advanced HIV-1 infection
- (2012) Antonios I. Papadopoulos et al. CYTOKINE
- Evaluation of Toll-like receptor and adaptor molecule polymorphisms for susceptibility to tuberculosis in a Colombian population
- (2012) D. Sánchez et al. International Journal of Immunogenetics
- Poxviral Protein A46 Antagonizes Toll-like Receptor 4 Signaling by Targeting BB Loop Motifs in Toll-IL-1 Receptor Adaptor Proteins to Disrupt Receptor:Adaptor Interactions
- (2012) Julianne Stack et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of polymorphisms of toll-like receptor (TLR) 4, TLR9, toll-interleukin 1 receptor domain containing adaptor protein (TIRAP) and FCGR2A genes in malaria susceptibility and severity in Burundian children
- (2012) Susanna Esposito et al. MALARIA JOURNAL
- The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock
- (2012) Ezra Aksoy et al. NATURE IMMUNOLOGY
- Association of TIRAP (MAL) gene polymorhisms with susceptibility to tuberculosis in a Chinese population
- (2011) Y.X. Zhang et al. GENETICS AND MOLECULAR RESEARCH
- Genetic variations in MyD88 adaptor-like are associated with atopic dermatitis
- (2011) Matsui INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Mal Mediates TLR-Induced Activation of CREB and Expression of IL-10
- (2011) M. Mellett et al. JOURNAL OF IMMUNOLOGY
- Genetic variation of TLR-4, TLR-9 and TIRAP genes in Iranian malaria patients
- (2011) Sedigheh Zakeri et al. MALARIA JOURNAL
- Poxvirus A46 protein binds to TIR domain-containing Mal/TIRAP via an α-helical sub-domain
- (2011) Shun-ichiro Oda et al. MOLECULAR IMMUNOLOGY
- TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding
- (2011) Masakiyo Sakaguchi et al. PLoS One
- TIRAP Ser180Leu polymorphism is associated with Behcet's disease
- (2011) O. Durrani et al. RHEUMATOLOGY
- Meta-analysis on the association of TIRAP S180L variant and tuberculosis susceptibility
- (2011) Ruifen Miao et al. TUBERCULOSIS
- Association between Single‐Nucleotide Polymorphisms inMal/TIRAPandInterleukin‐10Genes and Susceptibility to InvasiveHaemophilus influenzaeSerotype b Infection in Immunized Children
- (2010) Shamez N. Ladhani et al. CLINICAL INFECTIOUS DISEASES
- The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
- (2010) Taro Kawai et al. NATURE IMMUNOLOGY
- Toll-like receptor and TIRAP gene polymorphisms in pulmonary tuberculosis patients of South India
- (2010) P. Selvaraj et al. TUBERCULOSIS
- Toll-like receptor 4 signalling through MyD88 is essential to controlSalmonella entericaserovar Typhimurium infection, but not for the initiation of bacterial clearance
- (2009) Suzanne Talbot et al. IMMUNOLOGY
- Heterozygosity for the S180L Variant ofMAL/TIRAP,a Gene Expressing an Adaptor Protein in the Toll‐Like Receptor Pathway, Is Associated with Lower Risk of Developing Chronic Chagas Cardiomyopathy
- (2009) Rajendranath Ramasawmy et al. JOURNAL OF INFECTIOUS DISEASES
- TIRAP (MAL) S180L polymorphism is a common protective factor against developing tuberculosis and systemic lupus erythematosus
- (2008) John Castiblanco et al. INFECTION GENETICS AND EVOLUTION
- Analysis of association of the TIRAP (MAL) S180L variant and tuberculosis in three populations
- (2008) Sergey Nejentsev et al. NATURE GENETICS
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