Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes

Prevention of tuberculosis in macaques after intravenous BCG immunization

(2020) Patricia A. Darrah et al.   NATURE

Activation of CD8+ T Cell Responses after Melanoma Antigen Targeting to CD169+ Antigen Presenting Cells in Mice and Humans

(2019) Dieke van Dinther et al.   Cancers

Current Status of Immunotherapies for Treating Pancreatic Cancer

(2019) Annie A. Wu et al.   Current Oncology Reports

Programmed Cell Death Ligand-1 (PD-L1) and CD8 Expression Profiling Identify an Immunologic Subtype of Pancreatic Ductal Adenocarcinomas with Favorable Survival

(2019) Ludmila Danilova et al.   Cancer Immunology Research

PEGylated liposomes: immunological responses

(2019) Marwa Mohamed et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Anti-Siglec-1 antibodies block Ebola viral uptake and decrease cytoplasmic viral entry

(2019) Daniel Perez-Zsolt et al.   Nature Microbiology

From state-of-the-art treatments to novel therapies for advanced-stage pancreatic cancer

(2019) Christopher Nevala-Plagemann et al.   Nature Reviews Clinical Oncology

Constitutive Siglec-1 expression confers susceptibility to HIV-1 infection of human dendritic cell precursors

(2019) Nicolas Ruffin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

When Dendritic Cells Go Viral: The Role of Siglec-1 in Host Defense and Dissemination of Enveloped Viruses

(2019) Daniel Perez-Zsolt et al.   Viruses-Basel

Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population

(2019) Rebecca Leylek et al.   Cell Reports

The Immune Revolution: A Case for Priming, Not Checkpoint

(2018) Robert H. Vonderheide   CANCER CELL

CD169-positive sinus macrophages in the lymph nodes determine bladder cancer prognosis

(2018) Touko Asano et al.   CANCER SCIENCE

Human dendritic cell subsets: an update

(2018) Matthew Collin et al.   IMMUNOLOGY

Functional CD169 on Macrophages Mediates Interaction with Dendritic Cells for CD8 + T Cell Cross-Priming

(2018) Dieke van Dinther et al.   Cell Reports

Mouse DC-SIGN/CD209a as Target for Antigen Delivery and Adaptive Immunity

(2018) Sjoerd T. T. Schetters et al.   Frontiers in Immunology

Toll-Like Receptor 4 Triggering Promotes Cytosolic Routing of DC-SIGN-Targeted Antigens for Presentation on MHC Class I

(2018) Sophie K. Horrevorts et al.   Frontiers in Immunology

Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety

(2018) Kevin Van der Jeught et al.   ACS Nano

Membrane-wrapped nanoparticles probe divergent roles of GM3 and phosphatidylserine in lipid-mediated viral entry pathways

(2018) Fangda Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of Protein and Peptide Targeting for the Development of a CD169-Based Vaccination Strategy Against Melanoma

(2018) Dieke van Dinther et al.   Frontiers in Immunology

A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus

(2018) Pradeep D. Uchil et al.   Cell Host & Microbe

CD169+ Macrophages Capture and Dendritic Cells Instruct: The Interplay of the Gatekeeper and the General of the Immune System

(2018) Joanna Grabowska et al.   Frontiers in Immunology

Modulation of Immune Tolerance via Siglec-Sialic Acid Interactions

(2018) Joyce Lübbers et al.   Frontiers in Immunology

Current State of Dendritic Cell-Based Immunotherapy: Opportunities for in vitro Antigen Loading of Different DC Subsets?

(2018) Anne Huber et al.   Frontiers in Immunology

High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization

(2017) Marcela Alcántara-Hernández et al.   IMMUNITY

Targeting C-type lectin receptors: a high-carbohydrate diet for dendritic cells to improve cancer vaccines

(2017) Dieke van Dinther et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer

(2017) Vinod P. Balachandran et al.   NATURE

Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

(2017) Benjamin Mordmüller et al.   NATURE

Mapping the human DC lineage through the integration of high-dimensional techniques

(2017) Peter See et al.   SCIENCE

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Dendritic Cell-Based Immunotherapy: State of the Art and Beyond

(2016) K. F. Bol et al.   CLINICAL CANCER RESEARCH

Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species

(2016) Martin Guilliams et al.   IMMUNITY

The CD169 sialoadhesin molecule mediates cytotoxic T-cell responses to tumour apoptotic vesicles

(2016) Lane VC Black et al.   IMMUNOLOGY AND CELL BIOLOGY

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

(2016) Lena M. Kranz et al.   NATURE

SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions

(2016) F. Pucci et al.   SCIENCE

Route of administration of attenuated sporozoites is instrumental in rendering immunity against Plasmodia infection

(2016) Rajesh Parmar et al.   VACCINE

Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node

(2016) Yang Zhang et al.   eLife

New Developments in Liposomal Drug Delivery

(2015) Bhushan S. Pattni et al.   CHEMICAL REVIEWS

Mouse Siglec-1 Mediatestrans-Infection of Surface-bound Murine Leukemia Virus in a Sialic AcidN-Acyl Side Chain-dependent Manner

(2015) Elina Erikson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MPLA incorporation into DC-targeting glycoliposomes favours anti-tumour T cell responses

(2015) Martine A. Boks et al.   JOURNAL OF CONTROLLED RELEASE

Cross-presentation through langerin and DC-SIGN targeting requires different formulations of glycan-modified antigens

(2015) Cynthia M. Fehres et al.   JOURNAL OF CONTROLLED RELEASE

CD169+macrophages are sufficient for priming of CTLs with specificities left out by cross-priming dendritic cells

(2015) Caroline A. Bernhard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection

(2015) X. Sewald et al.   SCIENCE

Prognostic Significance of CD169+ Lymph Node Sinus Macrophages in Patients with Malignant Melanoma

(2015) Y. Saito et al.   Cancer Immunology Research

Virus Particle Release from Glycosphingolipid-Enriched Microdomains Is Essential for Dendritic Cell-Mediated Capture and Transfer of HIV-1 and Henipavirus

(2014) H. Akiyama et al.   JOURNAL OF VIROLOGY

Clinical use of dendritic cells for cancer therapy

(2014) Sébastien Anguille et al.   LANCET ONCOLOGY

Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

(2014) Samir Mitragotri et al.   NATURE REVIEWS DRUG DISCOVERY

Induction of Antigen-Specific Immunity with a Vaccine Targeting NY-ESO-1 to the Dendritic Cell Receptor DEC-205

(2014) M. V. Dhodapkar et al.   Science Translational Medicine

Glycosphingolipid-functionalized nanoparticles recapitulate CD169-dependent HIV-1 uptake and trafficking in dendritic cells

(2014) Xinwei Yu et al.   Nature Communications

Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer

(2013) Y Ino et al.   BRITISH JOURNAL OF CANCER

CD169-positive macrophages in regional lymph nodes are associated with a favorable prognosis in patients with colorectal carcinoma

(2013) Koji Ohnishi et al.   CANCER SCIENCE

Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation

(2013) N. Kawasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interferon-Inducible Mechanism of Dendritic Cell-Mediated HIV-1 Dissemination Is Dependent on Siglec-1/CD169

(2013) Wendy Blay Puryear et al.   PLoS Pathogens

Glycan-modified liposomes boost CD4+ and CD8+ T-cell responses by targeting DC-SIGN on dendritic cells

(2012) Wendy W.J. Unger et al.   JOURNAL OF CONTROLLED RELEASE

In Silico-Aided Design of a Glycan Ligand of Sialoadhesin for in Vivo Targeting of Macrophages

(2012) Corwin M. Nycholat et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antigen Delivery to Macrophages Using Liposomal Nanoparticles Targeting Sialoadhesin/CD169

(2012) Weihsu C. Chen et al.   PLoS One

HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells

(2012) W. B. Puryear et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sialoadhesin in recognition of self and non-self

(2012) Mariliis Klaas et al.   Seminars in Immunopathology

Siglec-1 Is a Novel Dendritic Cell Receptor That Mediates HIV-1 Trans-Infection Through Recognition of Viral Membrane Gangliosides

(2012) Nuria Izquierdo-Useros et al.   PLOS BIOLOGY

Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation

(2011) P. J. Tacken et al.   BLOOD

Effective collaboration between marginal metallophilic macrophages and CD8+ dendritic cells in the generation of cytotoxic T cells

(2009) R. Backer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sialoadhesin Expressed on IFN-Induced Monocytes Binds HIV-1 and Enhances Infectivity

(2008) Hans Rempel et al.   PLoS One

DEC-205/CD205+dendritic cells are abundant in the white pulp of the human spleen, including the border region between the red and white pulp

(2007) Maggi Pack et al.   IMMUNOLOGY