IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12Rβ1 internalization and suppress EAE

Roles of GM-CSF in the Pathogenesis of Autoimmune Diseases: An Update

(2019) Noushin Lotfi et al.   Frontiers in Immunology

Elevated expression of granulocyte-macrophage colony-stimulating factor receptor in multiple sclerosis lesions

(2018) Jaime Imitola et al.   JOURNAL OF NEUROIMMUNOLOGY

Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer’s pathology

(2018) Suresh B. Rangasamy et al.   JOURNAL OF CLINICAL INVESTIGATION

Aspirin ameliorates experimental autoimmune encephalomyelitis through interleukin-11–mediated protection of regulatory T cells

(2018) Susanta Mondal et al.   Science Signaling

Selective neutralization of IL-12 p40 monomer induces death in prostate cancer cells via IL-12–IFN-γ

(2017) Madhuchhanda Kundu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-12-polarized Th1 cells produce GM-CSF and induce EAE independent of IL-23

(2015) Heather M. Grifka-Walk et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases

(2015) Michele W L Teng et al.   NATURE MEDICINE

Cinnamon Ameliorates Experimental Allergic Encephalomyelitis in Mice via Regulatory T Cells: Implications for Multiple Sclerosis Therapy

(2015) Susanta Mondal et al.   PLoS One

Interleukin-12 (IL-12), but not IL-23, induces the expression of IL-7 in microglia and macrophages: implications for multiple sclerosis

(2013) Malabendu Jana et al.   IMMUNOLOGY

Induced CD4+Foxp3+ Regulatory T Cells in Immune Tolerance

(2012) Angelina M. Bilate et al.   Annual Review of Immunology

Protection of Tregs, Suppression of Th1 and Th17 Cells, and Amelioration of Experimental Allergic Encephalomyelitis by a Physically-Modified Saline

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Neuroimmune Pharmacological Control of EAE

(2010) Kalipada Pahan   Journal of Neuroimmune Pharmacology

Current Views on the Roles of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis

(2010) Mohamed El-behi et al.   Journal of Neuroimmune Pharmacology

Why did IL-12/IL-23 antibody therapy fail in multiple sclerosis?

(2009) Erin E Longbrake et al.   Expert Review of Neurotherapeutics

IL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12Rβ1

(2009) Malabendu Jana et al.   GLIA

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

Suppression of Regulatory T Cells by IL-12p40 Homodimer via Nitric Oxide

(2009) S. Brahmachari et al.   JOURNAL OF IMMUNOLOGY

Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Reduces Microglial and Astroglial Inflammatory Responses

(2009) S. Brahmachari et al.   JOURNAL OF IMMUNOLOGY

Functional Blocking Monoclonal Antibodies against IL-12p40 Homodimer Inhibit Adoptive Transfer of Experimental Allergic Encephalomyelitis

(2009) S. Mondal et al.   JOURNAL OF IMMUNOLOGY

Generation of Functional Blocking Monoclonal Antibodies Against Mouse Interleukin-12 p40 Homodimer and Monomer

(2008) Subhajit Dasgupta et al.   HYBRIDOMA

Induction of lymphotoxin-α by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70

(2008) Malabendu Jana et al.   IMMUNOLOGY

IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages

(2008) Malabendu Jana et al.   MOLECULAR IMMUNOLOGY

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology