TargetDB: A target information aggregation tool and tractability predictor

Precise tuning of gene expression levels in mammalian cells

(2019) Yale S. Michaels et al.   Nature Communications

TractaViewer: a genome-wide tool for preliminary assessment of therapeutic target druggability

(2019) Neil Pearson et al.   BIOINFORMATICS

Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens

(2019) Fiona M. Behan et al.   NATURE

Identifying and ranking potential driver genes of Alzheimer’s disease using multiview evidence aggregation

(2019) Sumit Mukherjee et al.   BIOINFORMATICS

The genetic risk of Alzheimer’s disease beyond APOE ε4: systematic review of Alzheimer’s genetic risk scores

(2018) Hannah Stocker et al.   Translational Psychiatry

A multi-omic atlas of the human frontal cortex for aging and Alzheimer’s disease research

(2018) Philip L. De Jager et al.   Scientific Data

Open Targets Platform: new developments and updates two years on

(2018) Denise Carvalho-Silva et al.   NUCLEIC ACIDS RESEARCH

Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation

(2018) Songhai Tian et al.   PLOS BIOLOGY

The 2018 Nucleic Acids Research database issue and the online molecular biology database collection

(2017) Daniel J Rigden et al.   NUCLEIC ACIDS RESEARCH

OUP accepted manuscript

(2017)   NUCLEIC ACIDS RESEARCH

DGIdb 3.0: a redesign and expansion of the drug–gene interaction database

(2017) Kelsy C Cotto et al.   NUCLEIC ACIDS RESEARCH

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Proteogenomic integration reveals therapeutic targets in breast cancer xenografts

(2017) Kuan-lin Huang et al.   Nature Communications

Pharos: Collating protein information to shed light on the druggable genome

(2016) Dac-Trung Nguyen et al.   NUCLEIC ACIDS RESEARCH

The ChEMBL database in 2017

(2016) Anna Gaulton et al.   NUCLEIC ACIDS RESEARCH

UniProt: the universal protein knowledgebase

(2016)   NUCLEIC ACIDS RESEARCH

From Proteomic Analysis to Potential Therapeutic Targets: Functional Profile of Two Lung Cancer Cell Lines, A549 and SW900, Widely Studied in Pre-Clinical Research

(2016) Luís Korrodi-Gregório et al.   PLoS One

InterMine: extensive web services for modern biology

(2014) Alex Kalderimis et al.   NUCLEIC ACIDS RESEARCH

Moving beyond Rules: The Development of a Central Nervous System Multiparameter Optimization (CNS MPO) Approach To Enable Alignment of Druglike Properties

(2010) Travis T. Wager et al.   ACS Chemical Neuroscience

Genomic Screening with RNAi: Results and Challenges

(2010) Stephanie Mohr et al.   Annual Review of Biochemistry

Understanding and Predicting Druggability. A High-Throughput Method for Detection of Drug Binding Sites

(2010) Peter Schmidtke et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fpocket: An open source platform for ligand pocket detection

(2009) Vincent Le Guilloux et al.   BMC BIOINFORMATICS