Melatonin alleviates sepsis-induced heart injury through activating the Nrf2 pathway and inhibiting the NLRP3 inflammasome
出版年份 2020 全文链接
标题
Melatonin alleviates sepsis-induced heart injury through activating the Nrf2 pathway and inhibiting the NLRP3 inflammasome
作者
关键词
-
出版物
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-09-16
DOI
10.1007/s00210-020-01972-5
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Regulation of Nrf2/Keap1 signalling in human skeletal muscle during exercise to exhaustion in normoxia, severe acute hypoxia and post-exercise ischaemia: Influence of metabolite accumulation and oxygenation
- (2020) Angel Gallego-Selles et al. Redox Biology
- The protective role of autophagy in sepsis
- (2019) Ying Feng et al. MICROBIAL PATHOGENESIS
- Melatonin Attenuates LPS-Induced Acute Depressive-Like Behaviors and Microglial NLRP3 Inflammasome Activation Through the SIRT1/Nrf2 Pathway
- (2019) Burak I. Arioz et al. Frontiers in Immunology
- STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3
- (2019) Ning Li et al. Redox Biology
- Melatonin protects against chromium(VI)-induced cardiac injury via activating the AMPK/Nrf2 pathway
- (2019) Jiayi Li et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation
- (2019) Qisheng Lin et al. Redox Biology
- Melatonin attenuates acute kidney ischemia/reperfusion injury in diabetic rats by activation of the SIRT1/Nrf2/HO-1 signaling pathway
- (2018) Si Shi et al. BIOSCIENCE REPORTS
- Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway
- (2018) Junmin Wang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Melatonin administration to wild-type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis
- (2017) Ibtissem Rahim et al. JOURNAL OF PINEAL RESEARCH
- Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis
- (2017) Flavia Lambertucci et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Protective role of heme oxygenase-1 in atrial remodeling
- (2016) Yung-Hsin Yeh et al. BASIC RESEARCH IN CARDIOLOGY
- Microglia antioxidant systems and redox signalling
- (2016) F Vilhardt et al. BRITISH JOURNAL OF PHARMACOLOGY
- Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism
- (2016) Agnieszka Loboda et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Cardiac dysfunction, mitochondrial architecture, energy production, and inflammatory pathways: Interrelated aspects in endotoxemia and sepsis
- (2016) Silvia Alvarez et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin
- (2016) Huayqui Volt et al. JOURNAL OF PINEAL RESEARCH
- Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network
- (2016) María E. Díaz-Casado et al. JOURNAL OF PINEAL RESEARCH
- Oxidative-Nitrosative Stress and Myocardial Dysfunctions in Sepsis: Evidence from the Literature and Postmortem Observations
- (2016) M. Neri et al. MEDIATORS OF INFLAMMATION
- The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update
- (2016) Meng-Chen Lu et al. MEDICINAL RESEARCH REVIEWS
- Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network
- (2016) Carolina Doerrier et al. MITOCHONDRION
- ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms
- (2015) Lulu Li et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice
- (2015) José A. García et al. FASEB JOURNAL
- Melatonin induces the expression of Nrf2-regulated antioxidant enzymes via PKC and Ca2+ influx activation in mouse pancreatic acinar cells
- (2015) Patricia Santofimia-Castaño et al. FREE RADICAL BIOLOGY AND MEDICINE
- Melatonin alleviates brain injury in mice subjected to cecal ligation and puncture via attenuating inflammation, apoptosis, and oxidative stress: the role of SIRT1 signaling
- (2015) Lei Zhao et al. JOURNAL OF PINEAL RESEARCH
- The Keap1-Nrf2-antioxidant response element pathway: A review of its regulation by melatonin and the proteasome
- (2015) Jerry Vriend et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Autophagy and apoptosis: where do they meet?
- (2014) Subhadip Mukhopadhyay et al. APOPTOSIS
- Self-consumption: the interplay of autophagy and apoptosis
- (2014) Guillermo Mariño et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Analysis of the role of Nrf2 in the expression of liver proteins in mice using two-dimensional gel-based proteomics
- (2014) Azman Abdullah et al. Pharmacological Reports
- The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia–reperfusion injury
- (2013) Øystein Sandanger et al. CARDIOVASCULAR RESEARCH
- The beneficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of iNOS and preservation of nNOS
- (2013) Francisco Ortiz et al. JOURNAL OF PINEAL RESEARCH
- The role of mitochondrial dysfunction in sepsis-induced multi-organ failure
- (2013) Mervyn Singer Virulence
- Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration
- (2013) K. M. Holmstrom et al. Biology Open
- Melatonin-mitochondria Interplay in Health and Disease
- (2012) Dario Acuna Castroviejo et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Small Molecule Modulators of Keap1-Nrf2-ARE Pathway as Potential Preventive and Therapeutic Agents
- (2012) Sadagopan Magesh et al. MEDICINAL RESEARCH REVIEWS
- Enhancing Nrf2 Pathway by Disruption of Keap1 in Myeloid Leukocytes Protects against Sepsis
- (2011) Xiaoni Kong et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- High Throughput Microplate Respiratory Measurements Using Minimal Quantities Of Isolated Mitochondria
- (2011) George W. Rogers et al. PLoS One
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- Sepsis and the heart
- (2009) J.D. Hunter et al. BRITISH JOURNAL OF ANAESTHESIA
- Immunodesign of experimental sepsis by cecal ligation and puncture
- (2009) Daniel Rittirsch et al. Nature Protocols
- Redox compartmentalization in eukaryotic cells
- (2008) Young-Mi Go et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
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