Melatonin attenuates acute kidney ischemia/reperfusion injury in diabetic rats by activation of the SIRT1/Nrf2/HO-1 signaling pathway

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Acute Kidney Injury and Progression of Diabetic Kidney Disease

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Ischemic acute kidney injury and klotho in renal transplantation

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Melatonin and Oxidative Stress in the Diabetic State: Clinical Implications and Potential Therapeutic Applications

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Neuroprotective Effects of Melatonin on Experimental Allergic Encephalomyelitis Mice Via Anti-Oxidative Stress Activity

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The crosstalk between Sirt1 and Keap1/Nrf2/ARE anti-oxidative pathway forms a positive feedback loop to inhibit FN and TGF-β1 expressions in rat glomerular mesangial cells

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Effects of sevoflurane on NF-кB and TNF-α expression in renal ischemia–reperfusion diabetic rats

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Activation of Nrf2/HO-1 Pathway by Glycogen Synthase Kinase-3β Inhibition Attenuates Renal Ischemia/Reperfusion Injury in Diabetic Rats

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Tucum-do-Cerrado (Bactris setosa Mart.) May Promote Anti-Aging Effect by Upregulating SIRT1-Nrf2 Pathway and Attenuating Oxidative Stress and Inflammation

(2017) Marcela da Cunha et al.   Nutrients

Melatonin Stimulates the SIRT1/Nrf2 Signaling Pathway Counteracting Lipopolysaccharide (LPS)-Induced Oxidative Stress to Rescue Postnatal Rat Brain

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SIRT1 exerts protective effects against paraquat-induced injury in mouse type II alveolar epithelial cells by deacetylating NRF2 in vitro

(2016) YING-WEI DING et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

On the significance of an alternate pathway of melatonin synthesis via 5-methoxytryptamine: comparisons across species

(2016) Dun-Xian Tan et al.   JOURNAL OF PINEAL RESEARCH

Melatonin Attenuates Early Brain Injury via the Melatonin Receptor/Sirt1/NF-κB Signaling Pathway Following Subarachnoid Hemorrhage in Mice

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Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds

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Thioredoxin-Interacting Protein Mediates NLRP3 Inflammasome Activation Involved in the Susceptibility to Ischemic Acute Kidney Injury in Diabetes

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Melatonin prevents acute kidney injury in severely burned rats via the activation of SIRT1

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Selective inhibition of PTEN preserves ischaemic post-conditioning cardioprotection in STZ-induced Type 1 diabetic rats: role of the PI3K/Akt and JAK2/STAT3 pathways

(2015) R. Xue et al.   CLINICAL SCIENCE

Reduced silent information regulator 1 signaling exacerbates myocardial ischemia-reperfusion injury in type 2 diabetic rats and the protective effect of melatonin

(2015) Liming Yu et al.   JOURNAL OF PINEAL RESEARCH

Melatonin alleviates brain injury in mice subjected to cecal ligation and puncture via attenuating inflammation, apoptosis, and oxidative stress: the role of SIRT1 signaling

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Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells

(2015) Kaipeng Huang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2–ARE signaling pathway as a potential mechanism

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Effects of melatonin on the serum levels of pro-inflammatory cytokines and tissue injury after renal ischemia reperfusion in rats

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Evaluation of Renal Protection From High Doses of Melatonin in an Experimental Model of Renal Ischemia and Reperfusion in Hyperglycemic Rats

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Anti-aging molecule, Sirt1: a novel therapeutic target for diabetic nephropathy

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Melatonin: Buffering the Immune System

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Role of Nrf2 in protection against acute kidney injury

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Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-κB-mediated inflammatory response

(2013) Tao Jiang et al.   KIDNEY INTERNATIONAL

Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway

(2013) Ulkan Kilic et al.   Nutrition & Metabolism

SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential

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Sirtuins and renal diseases: relationship with aging and diabetic nephropathy

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Mammalian Sirt1: insights on its biological functions

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Alteration of Forkhead Box O (Foxo4) Acetylation Mediates Apoptosis of Podocytes in Diabetes Mellitus

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Mammalian Sirtuins: Biological Insights and Disease Relevance

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Photoentrainment in blind and sighted rodent species: responses to photophase light with different wavelengths

(2010) A. E. Zubidat et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Melatonin protects kidney grafts from ischemia/reperfusion injury through inhibition of NF-kB and apoptosis after experimental kidney transplantation

(2009) Zhanqing Li et al.   JOURNAL OF PINEAL RESEARCH

Effect of melatonin on testicular ischemia/reperfusion injury in rats: is this effect related to the proinflammatory cytokines?

(2007) Zehra Kurcer et al.   FERTILITY AND STERILITY