Brain transforms natural killer cells that exacerbate brain edema after intracerebral hemorrhage

Deferoxamine mesylate in patients with intracerebral haemorrhage (i-DEF): a multicentre, randomised, placebo-controlled, double-blind phase 2 trial

(2019) Magdy Selim et al.   LANCET NEUROLOGY

Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial

(2019) Daniel F Hanley et al.   LANCET

Siponimod (BAF-312) Attenuates Perihemorrhagic Edema And Improves Survival in Experimental Intracerebral Hemorrhage

(2019) Tobias Bobinger et al.   STROKE

High-Dimensional Single-Cell Analysis Identifies Organ-Specific Signatures and Conserved NK Cell Subsets in Humans and Mice

(2018) Adeline Crinier et al.   IMMUNITY

A TSPO ligand attenuates brain injury after intracerebral hemorrhage

(2017) Minshu Li et al.   FASEB JOURNAL

Brain Ischemia Suppresses Immunity in the Periphery and Brain via Different Neurogenic Innervations

(2017) Qiang Liu et al.   IMMUNITY

Selective NLRP3 (Pyrin Domain–Containing Protein 3) Inflammasome Inhibitor Reduces Brain Injury After Intracerebral Hemorrhage

(2017) Honglei Ren et al.   STROKE

Mechanism and Therapy of Brain Edema after Intracerebral Hemorrhage

(2016) Haiping Zheng et al.   CEREBROVASCULAR DISEASES

Rate of Perihematomal Edema Expansion Predicts Outcome After Intracerebral Hemorrhage

(2016) Sebastian Urday et al.   CRITICAL CARE MEDICINE

Colony stimulating factor 1 receptor inhibition eliminates microglia and attenuates brain injury after intracerebral hemorrhage

(2016) Minshu Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Rate of perihaematomal oedema expansion is associated with poor clinical outcomes in intracerebral haemorrhage

(2016) Santosh B Murthy et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation

(2016) Qiang Liu et al.   NATURE NEUROSCIENCE

Astrocyte-derived interleukin-15 exacerbates ischemic brain injury via propagation of cellular immunity

(2016) Minshu Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune interventions in stroke

(2015) Ying Fu et al.   Nature Reviews Neurology

Targeting secondary injury in intracerebral haemorrhage—perihaematomal oedema

(2015) Sebastian Urday et al.   Nature Reviews Neurology

Accumulation of natural killer cells in ischemic brain tissues and the chemotactic effect of IP-10

(2014) Yao Zhang et al.   Journal of Neuroinflammation

Ischemic neurons recruit natural killer cells that accelerate brain infarction

(2014) Y. Gan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leukocyte Invasion of the Brain After Experimental Intracerebral Hemorrhage in Mice

(2014) Eva Mracsko et al.   STROKE

Neuroinflammation after intracerebral hemorrhage

(2014) Eva Mracsko et al.   Frontiers in Cellular Neuroscience

Alterations of natural killer cells in traumatic brain injury

(2014) Xiao-Dong Kong et al.   Neuroscience Bulletin

Fingolimod for the Treatment of Intracerebral Hemorrhage

(2014) Ying Fu et al.   JAMA Neurology

Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition

(2013) Eric O. Long et al.   Annual Review of Immunology

Natural killer cells and their receptors in multiple sclerosis

(2012) Gurman Kaur et al.   BRAIN

Intracerebral haemorrhage: mechanisms of injury and therapeutic targets

(2012) Richard F Keep et al.   LANCET NEUROLOGY

Neutrophil Depletion Reduces Blood-Brain Barrier Breakdown, Axon Injury, and Inflammation After Intracerebral Hemorrhage

(2011) Iska Moxon-Emre et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE

Molecular Pathophysiology of Cerebral Hemorrhage

(2011) Jaroslaw Aronowski et al.   STROKE

NKG2D Is Required for NK Cell Activation and Function in Response to E1-Deleted Adenovirus

(2010) J. Zhu et al.   JOURNAL OF IMMUNOLOGY

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

(2010) Volker Brinkmann et al.   NATURE REVIEWS DRUG DISCOVERY

Fingolimod is a potential novel therapy for multiple sclerosis

(2010) Orhan Aktas et al.   Nature Reviews Neurology

Preclinical and clinical research on inflammation after intracerebral hemorrhage

(2010) Jian Wang   PROGRESS IN NEUROBIOLOGY

Intracerebral haemorrhage

(2009) Adnan I Qureshi et al.   LANCET