Colony stimulating factor 1 receptor inhibition eliminates microglia and attenuates brain injury after intracerebral hemorrhage

Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation

(2016) Qiang Liu et al.   NATURE NEUROSCIENCE

Selective Sphingosine-1-Phosphate Receptor 1 Modulation Attenuates Experimental Intracerebral Hemorrhage

(2016) Na Sun et al.   STROKE

Inhibition of colony stimulating factor-1 receptor improves antitumor efficacy of BRAF inhibition

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CSF1 Receptor Targeting in Prostate Cancer Reverses Macrophage-Mediated Resistance to Androgen Blockade Therapy

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Infiltration of circulating myeloid cells through CD95L contributes to neurodegeneration in mice

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Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice

(2015) Nabil N. Dagher et al.   Journal of Neuroinflammation

Immune interventions in stroke

(2015) Ying Fu et al.   Nature Reviews Neurology

Targeting secondary injury in intracerebral haemorrhage—perihaematomal oedema

(2015) Sebastian Urday et al.   Nature Reviews Neurology

Colony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization

(2015) Jason H. Stafford et al.   NEURO-ONCOLOGY

Fingolimod alters inflammatory mediators and vascular permeability in intracerebral hemorrhage

(2015) Yu-Jing Li et al.   Neuroscience Bulletin

Characterizing Newly Repopulated Microglia in the Adult Mouse: Impacts on Animal Behavior, Cell Morphology, and Neuroinflammation

(2015) Monica R. P. Elmore et al.   PLoS One

Toll-like receptor 2/4 heterodimer mediates inflammatory injury in intracerebral hemorrhage

(2014) Yan-Chun Wang et al.   ANNALS OF NEUROLOGY

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

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Ischemic neurons recruit natural killer cells that accelerate brain infarction

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Neuroinflammation after intracerebral hemorrhage

(2014) Eva Mracsko et al.   Frontiers in Cellular Neuroscience

Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy

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Microglial Responses after Ischemic Stroke and Intracerebral Hemorrhage

(2013) Roslyn A. Taylor et al.   Clinical & Developmental Immunology

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Delayed Bone Regeneration Is Linked to Chronic Inflammation in Murine Muscular Dystrophy

(2013) Rana Abou-Khalil et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival

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Beyond Stem Cells: Self-Renewal of Differentiated Macrophages

(2013) M. H. Sieweke et al.   SCIENCE

The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation

(2012) Sayan Nandi et al.   DEVELOPMENTAL BIOLOGY

What Sequences on High-Field MR Best Depict Temporal Resolution of Experimental ICH and Edema Formation in Mice?

(2012) Mingchang Li et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS

(2012) Oleg Butovsky et al.   JOURNAL OF CLINICAL INVESTIGATION

Intracerebral haemorrhage: mechanisms of injury and therapeutic targets

(2012) Richard F Keep et al.   LANCET NEUROLOGY

The immunology of acute stroke

(2012) Ángel Chamorro et al.   Nature Reviews Neurology

Stroke and the immune system: from pathophysiology to new therapeutic strategies

(2011) Richard Macrez et al.   LANCET NEUROLOGY

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Absence of Colony Stimulation Factor-1 Receptor Results in Loss of Microglia, Disrupted Brain Development and Olfactory Deficits

(2011) Bryna Erblich et al.   PLoS One

Minocycline-Induced Attenuation of Iron Overload and Brain Injury After Experimental Intracerebral Hemorrhage

(2011) Fan Zhao et al.   STROKE

Central nervous system (CNS)–resident natural killer cells suppress Th17 responses and CNS autoimmune pathology

(2010) Junwei Hao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Preclinical and clinical research on inflammation after intracerebral hemorrhage

(2010) Jian Wang   PROGRESS IN NEUROBIOLOGY

Rodent Models of Intracerebral Hemorrhage

(2010) C. L. MacLellan et al.   STROKE

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Colony-Stimulating Factor-1 Receptor Inhibitors for the Treatment of Cancer and Inflammatory Disease

(2009) Sharmila Patel et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

A mouse model of intracerebral hemorrhage using autologous blood infusion

(2008) Michal A Rynkowski et al.   Nature Protocols

Discovery of a Cytokine and Its Receptor by Functional Screening of the Extracellular Proteome

(2008) H. Lin et al.   SCIENCE