MiR-17-92 enriched exosomes derived from multipotent mesenchymal stromal cells enhance axon-myelin remodeling and motor electrophysiological recovery after stroke

Exosomes — beyond stem cells for restorative therapy in stroke and neurological injury

(2019) Zheng Gang Zhang et al.   Nature Reviews Neurology

Myelin in the Central Nervous System: Structure, Function, and Pathology

(2019) Christine Stadelmann et al.   PHYSIOLOGICAL REVIEWS

Factors affecting post-stroke motor recovery: Implications on neurotherapy after brain injury

(2018) Ali Alawieh et al.   BEHAVIOURAL BRAIN RESEARCH

Role of Exosomes Derived from miR-133b Modified MSCs in an Experimental Rat Model of Intracerebral Hemorrhage

(2018) Haitao Shen et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells

(2018) Manuela Spagnuolo et al.   HAEMATOLOGICA

Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury

(2017) Yanlu Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Intranasal MSC-derived A1-exosomes ease inflammation, and prevent abnormal neurogenesis and memory dysfunction after status epilepticus

(2017) Qianfa Long et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-17–92 Cluster in Exosomes Enhance Neuroplasticity and Functional Recovery After Stroke in Rats

(2017) Hongqi Xin et al.   STROKE

Exosome Mediated Delivery of miR-124 Promotes Neurogenesis after Ischemia

(2017) Jialei Yang et al.   Molecular Therapy-Nucleic Acids

Cholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling

(2016) E. S. Mathews et al.   JOURNAL OF NEUROSCIENCE

Exosomes Derived from Mesenchymal Stromal Cells Promote Axonal Growth of Cortical Neurons

(2016) Yi Zhang et al.   MOLECULAR NEUROBIOLOGY

Emerging potential of exosomes and noncoding microRNAs for the treatment of neurological injury/diseases

(2015) Michael Chopp et al.   EXPERT OPINION ON EMERGING DRUGS

Oligodendrocytes: Myelination and Axonal Support

(2015) Mikael Simons et al.   Cold Spring Harbor Perspectives in Biology

Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression

(2015) Thorsten R. Doeppner et al.   Stem Cells Translational Medicine

Gap43 Transcription Modulation in the Adult Brain Depends on Sensory Activity and Synaptic Cooperation

(2014) Nicole Rosskothen-Kuhl et al.   PLoS One

Exosomes/miRNAs as mediating cell-based therapy of stroke

(2014) Hongqi Xin et al.   Frontiers in Cellular Neuroscience

Akt/mTOR signalling in myelination

(2013) Camilla Norrmén et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Systemic Administration of Exosomes Released from Mesenchymal Stromal Cells Promote Functional Recovery and Neurovascular Plasticity After Stroke in Rats

(2013) Hongqi Xin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The MicroRNA-17-92 Cluster Enhances Axonal Outgrowth in Embryonic Cortical Neurons

(2013) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Long-Term Post-Stroke Changes Include Myelin Loss, Specific Deficits in Sensory and Motor Behaviors and Complex Cognitive Impairment Detected Using Active Place Avoidance

(2013) Jin Zhou et al.   PLoS One

MiR-133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome-Enriched Extracellular Particles

(2013) Hongqi Xin et al.   STEM CELLS

Axonal Remodeling of the Corticospinal Tract in the Spinal Cord Contributes to Voluntary Motor Recovery After Stroke in Adult Mice

(2013) Zhongwu Liu et al.   STROKE

MicroRNA Cluster miR-17-92 Regulates Neural Stem Cell Expansion and Transition to Intermediate Progenitors in the Developing Mouse Neocortex

(2013) Shan Bian et al.   Cell Reports

Concepts and Methods for the Study of Axonal Regeneration in the CNS

(2012) Mark H. Tuszynski et al.   NEURON

Systemically administered human bone marrow-derived mesenchymal stem home into peripheral organs but do not induce neuroprotective effects in the MCAo-mouse model for cerebral ischemia

(2012) Barbara Steiner et al.   NEUROSCIENCE LETTERS

Assessing the Integrity of Corticospinal Pathways From Primary and Secondary Cortical Motor Areas After Stroke

(2012) Robert Schulz et al.   STROKE

Wnt/ -Catenin Signaling Is an Essential and Direct Driver of Myelin Gene Expression and Myelinogenesis

(2011) M. Tawk et al.   JOURNAL OF NEUROSCIENCE

Comparison of transcranial magnetic stimulation measures obtained at rest and under active conditions and their reliability

(2011) Suzy Ngomo et al.   JOURNAL OF NEUROSCIENCE METHODS

Subacute intranasal administration of tissue plasminogen activator increases functional recovery and axonal remodeling after stroke in rats

(2011) Zhongwu Liu et al.   NEUROBIOLOGY OF DISEASE

Exosomes: Extracellular organelles important in intercellular communication

(2010) Suresh Mathivanan et al.   Journal of Proteomics

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

(2010) Kai Liu et al.   NATURE NEUROSCIENCE

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

(2009) S. P.J. Fancy et al.   GENES & DEVELOPMENT

Motor recovery after stroke: a systematic review

(2009) Peter Langhorne et al.   LANCET NEUROLOGY

Remodeling of the Corticospinal Innervation and Spontaneous Behavioral Recovery After Ischemic Stroke in Adult Mice

(2009) Zhongwu Liu et al.   STROKE

Contralesional Axonal Remodeling of the Corticospinal System in Adult Rats After Stroke and Bone Marrow Stromal Cell Treatment

(2008) Zhongwu Liu et al.   STROKE

Evaluation of corticospinal axon loss by fluorescent dye tracing in mice with experimental autoimmune encephalomyelitis

(2007) Zhongwu Liu et al.   JOURNAL OF NEUROSCIENCE METHODS