Emerging Links between Control of Mitochondrial Protein ATAD3A and Cancer

Recurrent De Novo NAHR Reciprocal Duplications in the ATAD3 Gene Cluster Cause a Neurogenetic Trait with Perturbed Cholesterol and Mitochondrial Metabolism

(2020) Adam C. Gunning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Zn 2+ and Ca 2+ ‐binding S100B and S100A1 proteins: beyond the myths

(2020) Jacques Baudier et al.   BIOLOGICAL REVIEWS

A splice variant in ATAD3A expands the clinical and genetic spectrum of Harel-Yoon syndrome

(2020) Ilana Hanes et al.   Neurology-Genetics

Mitochondrial dysfunction caused by novel ATAD3A mutations

(2020) Nathalie Dorison et al.   MOLECULAR GENETICS AND METABOLISM

Prohibitins: A Critical Role in Mitochondrial Functions and Implication in Diseases

(2019) Anna Signorile et al.   Cells

ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects

(2019) Yuanyuan Zhao et al.   Nature Communications

Prognostic value of ATAD3 gene cluster expression in hepatocellular carcinoma

(2019) Xiaoling Liu et al.   Oncology Letters

Novel ATAD3A recessive mutation associated to fatal cerebellar hypoplasia with multiorgan involvement and mitochondrial structural abnormalities

(2019) Susana Peralta et al.   MOLECULAR GENETICS AND METABOLISM

Mitochondrial ATAD3A regulates milk biosynthesis and proliferation of mammary epithelial cells from dairy cow via the mTOR pathway

(2018) Dongying Chen et al.   CELL BIOLOGY INTERNATIONAL

ATAD3 controls mitochondrial cristae structure in mouse muscle, influencing mtDNA replication and cholesterol levels

(2018) Susana Peralta et al.   JOURNAL OF CELL SCIENCE

ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia

(2017) Helen M. Cooper et al.   HUMAN MOLECULAR GENETICS

Interaction of Mitochondria with the Endoplasmic Reticulum and Plasma Membrane in Calcium Homeostasis, Lipid Trafficking and Mitochondrial Structure

(2017) Jędrzej Szymański et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

S100B expression in breast cancer as a predictive marker for cancer metastasis

(2017) Meng-Chi Yen et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

The mammalian phosphate carrier SLC25A3 is a mitochondrial copper transporter required for cytochromecoxidase biogenesis

(2017) Aren Boulet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recurrent De Novo and Biallelic Variation of ATAD3A , Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes

(2016) Tamar Harel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Resveratrol inhibits lipogenesis of 3T3-L1 and SGBS cells by inhibition of insulin signaling and mitochondrial mass increase

(2016) Shuijie Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Control of mitochondrial function and cell growth by the atypical cadherin Fat1

(2016) Longyue L. Cao et al.   NATURE

WASF3 provides the conduit to facilitate invasion and metastasis in breast cancer cells through HER2/HER3 signaling

(2016) Y Teng et al.   ONCOGENE

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether

(2016) Deborah Naon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UbiNet: an online resource for exploring the functional associations and regulatory networks of protein ubiquitylation

(2016) Van-Nui Nguyen et al.   Database-The Journal of Biological Databases and Curation

Mitochondria-Associated Membrane Formation in Hormone-Stimulated Leydig Cell Steroidogenesis: Role of ATAD3

(2015) Leeyah Issop et al.   ENDOCRINOLOGY

Three Functions of Cadherins in Cell Adhesion

(2013) Jean-Léon Maître et al.   CURRENT BIOLOGY

Mitochondrial protein ATPase family, AAA domain containing 3A correlates with radioresistance in glioblastoma

(2013) W.-C. You et al.   NEURO-ONCOLOGY

Protein kinase C and cancer: what we know and what we do not

(2013) R Garg et al.   ONCOGENE

WASF3 regulates miR-200 inactivation by ZEB1 through suppression of KISS1 leading to increased invasiveness in breast cancer cells

(2013) Y Teng et al.   ONCOGENE

Atad3 Function Is Essential for Early Post-Implantation Development in the Mouse

(2013) Tobias Goller et al.   PLoS One

Integrative Analysis of Deep Sequencing Data Identifies Estrogen Receptor Early Response Genes and Links ATAD3B to Poor Survival in Breast Cancer

(2013) Kristian Ovaska et al.   PLoS Computational Biology

Mitochondrial Complex III Deficiency Caused by a HomozygousUQCRC2Mutation Presenting with Neonatal-Onset Recurrent Metabolic Decompensation

(2012) Noriko Miyake et al.   HUMAN MUTATION

ATAD3, a vital membrane bound mitochondrial ATPase involved in tumor progression

(2012) Shuijie Li et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

ATAD3B is a human embryonic stem cell specific mitochondrial protein, re-expressed in cancer cells, that functions as dominant negative for the ubiquitous ATAD3A

(2012) Nicolas Merle et al.   MITOCHONDRION

Identification of a Dynamic Mitochondrial Protein Complex Driving Cholesterol Import, Trafficking, and Metabolism to Steroid Hormones

(2012) Malena B. Rone et al.   MOLECULAR ENDOCRINOLOGY

New insights into the regulation and cellular functions of the ARP2/3 complex

(2012) Jeremy D. Rotty et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis

(2012) J. He et al.   NUCLEIC ACIDS RESEARCH

Structure and function of the AAA+ nucleotide binding pocket

(2011) Petra Wendler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Steroid hormone receptors in cancer development: A target for cancer therapeutics

(2010) Nihal Ahmad et al.   CANCER LETTERS

Topological analysis of ATAD3A insertion in purified human mitochondria

(2010) Arnaud Hubstenberger et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

ATPase family AAA domain-containing 3A is a novel anti-apoptotic factor in lung adenocarcinoma cells

(2010) H.-Y. Fang et al.   JOURNAL OF CELL SCIENCE

The Calcium-Dependent Interaction between S100B and the Mitochondrial AAA ATPase ATAD3A and the Role of This Complex in the Cytoplasmic Processing of ATAD3A

(2010) Benoît Gilquin et al.   MOLECULAR AND CELLULAR BIOLOGY

The AAA+ ATPase ATAD3A Controls Mitochondrial Dynamics at the Interface of the Inner and Outer Membranes

(2010) B. Gilquin et al.   MOLECULAR AND CELLULAR BIOLOGY

Why are tumour blood vessels abnormal and why is it important to know?

(2009) J A Nagy et al.   BRITISH JOURNAL OF CANCER

Functional organization of mammalian mitochondrial DNA in nucleoids: History, recent developments, and future challenges

(2009) Johannes N. Spelbrink   IUBMB LIFE

C. elegans ATAD-3 Is Essential for Mitochondrial Activity and Development

(2009) Michael Hoffmann et al.   PLoS One

ATAD 3A and ATAD 3B are distal 1p-located genes differentially expressed in human glioma cell lines and present in vitro anti-oncogenic and chemoresistant properties

(2008) Arnaud Hubstenberger et al.   EXPERIMENTAL CELL RESEARCH