标题
Melatonin and Autophagy in Aging-Related Neurodegenerative Diseases
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 19, Pages 7174
出版商
MDPI AG
发表日期
2020-09-29
DOI
10.3390/ijms21197174
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Picalm reduction exacerbates tau pathology in a murine tauopathy model
- (2020) Kunie Ando et al. ACTA NEUROPATHOLOGICA
- Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease
- (2020) Sandra Franco-Iborra et al. Autophagy
- Neuroregeneration: Regulation in Neurodegenerative Diseases and Aging
- (2020) N. V. Bobkova et al. BIOCHEMISTRY-MOSCOW
- Autophagy and disease: unanswered questions
- (2020) Ying Yang et al. CELL DEATH AND DIFFERENTIATION
- Quantitative Phosphoproteomic Analysis in Alpha-Synuclein Transgenic Mice Reveals the Involvement of Aberrant p25/Cdk5 Signaling in Early-stage Parkinson’s Disease
- (2020) Feng He et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- 11-Methoxytabersonine Induces Necroptosis with Autophagy through AMPK/mTOR and JNK Pathways in Human Lung Cancer Cells
- (2020) Di Ge et al. CHEMICAL & PHARMACEUTICAL BULLETIN
- Mitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatment
- (2020) Saeed Mehrzadi et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Astragalus polysaccharide exerts anti-Parkinson via activating the PI3K/AKT/mTOR pathway to increase cellular autophagy level in vitro
- (2020) Yinyin Tan et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Intracellular Calcium Dysregulation by the Alzheimer’s Disease-Linked Protein Presenilin 2
- (2020) Luisa Galla et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Importance of Melatonin in Assisted Reproductive Technology and Ovarian Aging
- (2020) Hiroshi Tamura et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- β2-adrenergic agonists rescue lysosome acidification and function in PSEN1 deficiency by reversing defective ER to lysosome delivery of ClC-7
- (2020) Ju-Hyun Lee et al. JOURNAL OF MOLECULAR BIOLOGY
- Initiation and propagation of α-synuclein aggregation in the nervous system
- (2020) Baraa A. Hijaz et al. Molecular Neurodegeneration
- Schizandrol A protects against Aβ1–42-induced autophagy via activation of PI3K/AKT/mTOR pathway in SH-SY5Y cells and primary hippocampal neurons
- (2020) Lin Song et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- A new threat to dopamine neurons: the downside of artificial light
- (2020) Irene Fasciani et al. NEUROSCIENCE
- The PINK1–Parkin axis: An Overview
- (2020) Keiji Tanaka NEUROSCIENCE RESEARCH
- β-Arrestin2 oligomers impair the clearance of pathological tau and increase tau aggregates
- (2020) Jung-A A. Woo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epidemiology of neurological diseases in older adults
- (2020) J. Dumurgier et al. REVUE NEUROLOGIQUE
- In Vitro CRISPR/Cas9-Directed Gene Editing to Model LRRK2 G2019S Parkinson’s Disease in Common Marmosets
- (2020) Scott C. Vermilyea et al. Scientific Reports
- Dexmedetomidine Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Enhancing Autophagy Through Inhibition of the PI3K/AKT/mTOR Pathway
- (2020) Yuan Zhao et al. Frontiers in Pharmacology
- Degradation of the Tumor Suppressor PDCD4 Is Impaired by the Suppression of p62/SQSTM1 and Autophagy
- (2020) M. Manirujjaman et al. Cells
- Examining aggregates through the eyes of WDFY3/Alfy
- (2020) Leora Fox et al. Autophagy
- Autophagy-dependent cancer cells circumvent loss of the upstream regulator RB1CC1/FIP200 and loss of LC3 conjugation by similar mechanisms
- (2020) Christina G. Towers et al. Autophagy
- CYLD is a causative gene for frontotemporal dementia – amyotrophic lateral sclerosis
- (2020) Carol Dobson-Stone et al. BRAIN
- N-degron-mediated degradation and regulation of mitochondrial PINK1 kinase
- (2020) Mohamed A. Eldeeb et al. CURRENT GENETICS
- Role of Alcohol Drinking in Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis
- (2020) Bin Peng et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Melatonin inhibits cytosolic mitochondrial DNA–induced neuroinflammatory signaling in accelerated aging and neurodegeneration
- (2020) Abhishek Jauhari et al. JOURNAL OF CLINICAL INVESTIGATION
- Cannabidiol exerts protective effects in an in vitro model of Parkinson's disease activating AKT/mTOR pathway
- (2020) Agnese Gugliandolo et al. FITOTERAPIA
- Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells
- (2019) Alexander Agrotis et al. Autophagy
- Biological Functions of Autophagy Genes: A Disease Perspective
- (2019) Beth Levine et al. CELL
- A VPS33A-binding motif on syntaxin17 controls autophagy completion in mammalian cells
- (2019) Rebecca S Saleeb et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Galangin decreases p‑tau, Aβ42 and β‑secretase levels, and suppresses autophagy in okadaic acid‑induced PC12 cells via an Akt/GSK3β/mTOR signaling‑dependent mechanism
- (2019) Liping Huang et al. Molecular Medicine Reports
- A Mammalian Mitophagy Receptor, Bcl2-L-13, Recruits the ULK1 Complex to Induce Mitophagy
- (2019) Tomokazu Murakawa et al. Cell Reports
- Tau and mTOR: The Hotspots for Multifarious Diseases in Alzheimer's Development
- (2019) Zeba Mueed et al. Frontiers in Neuroscience
- Patient-Specific iPSC-Derived Astrocytes Contribute to Non-Cell-Autonomous Neurodegeneration in Parkinson's Disease
- (2019) Angelique di Domenico et al. Stem Cell Reports
- PARP Inhibitors and Parkinson’s Disease
- (2019) Abby L. Olsen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Molecular Basis of Alzheimer’s Disease: Focus on Mitochondria
- (2019) Darryll M.A. Oliver et al. JOURNAL OF ALZHEIMERS DISEASE
- A PARP-1 Feed-Forward Mechanism To Accelerate α-Synuclein Toxicity in Parkinson’s Disease
- (2019) Buyan Pan et al. BIOCHEMISTRY
- Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway
- (2019) Abubakar Wani et al. Autophagy
- TP53INP2 contributes to autophagosome formation by promoting LC3-ATG7 interaction
- (2019) Zhiyuan You et al. Autophagy
- Small molecule-driven NLRP3 inflammation inhibition via interplay between ubiquitination and autophagy: implications for Parkinson disease
- (2019) Xiaojuan Han et al. Autophagy
- Cell death: a review of the major forms of apoptosis, necrosis and autophagy
- (2019) Mark S D’Arcy CELL BIOLOGY INTERNATIONAL
- EPPS treatment attenuates traumatic brain injury in mice by reducing Aβ burden and ameliorating neuronal autophagic flux
- (2019) Angela Melinda A. Anthony Jalin et al. EXPERIMENTAL NEUROLOGY
- Exocyst Subcomplex Functions in Autophagosome Biogenesis by Regulating Atg9 Trafficking
- (2019) Sunaina Singh et al. JOURNAL OF MOLECULAR BIOLOGY
- Melatonin Alleviates Cognition Impairment by Antagonizing Brain Insulin Resistance in Aged Rats Fed a High‐Fat Diet
- (2019) Jiqu Xu et al. JOURNAL OF PINEAL RESEARCH
- DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B
- (2019) Xiaoyu Tian et al. Autophagy
- p62/SQSTM1 protects against cisplatin-induced oxidative stress in kidneys by mediating the cross talk between autophagy and the Keap1-Nrf2 signalling pathway
- (2019) Weitang Liao et al. FREE RADICAL RESEARCH
- Melatonin in Alzheimer’s Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer’s Neuropathology
- (2019) Md. Farhad Hossain et al. MOLECULAR NEUROBIOLOGY
- Autophagy Induction by Bexarotene Promotes Mitophagy in Presenilin 1 Familial Alzheimer’s Disease iPSC-Derived Neural Stem Cells
- (2019) Patricia Martín-Maestro et al. MOLECULAR NEUROBIOLOGY
- Endo-lysosomal dysregulations and late-onset Alzheimer’s disease: impact of genetic risk factors
- (2019) Zoë P. Van Acker et al. Molecular Neurodegeneration
- Therapeutic approaches to enhance PINK1/Parkin mediated mitophagy for the treatment of Parkinson’s disease
- (2019) Silke Miller et al. NEUROSCIENCE LETTERS
- Upregulation of the Autophagy Adaptor p62/SQSTM1 Prolongs Health and Lifespan in Middle-Aged Drosophila
- (2019) Ricardo Aparicio et al. Cell Reports
- The role of chaperone-mediated autophagy in neurotoxicity induced by alpha-synuclein after methamphetamine exposure
- (2019) Leping Sun et al. Brain and Behavior
- Autophagy Is a Common Degradation Pathway for Bunina Bodies and TDP-43 Inclusions in Amyotrophic Lateral Sclerosis
- (2019) Fumiaki Mori et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- AAV-Mediated Expression of Dominant-Negative ULK1 Increases Neuronal Survival and Enhances Motor Performance in the MPTP Mouse Model of Parkinson’s Disease
- (2019) Dirk Balke et al. MOLECULAR NEUROBIOLOGY
- Autophagy regulator Atg9 is degraded by the proteasome
- (2019) Guohui Hu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Effect of Mutations in SOD1 and C9orf72 Genes on Autophagy in Lymphomonocytes in Myotrophic Lateral Sclerosis
- (2019) I. A. Kochergin et al. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
- Differential activation of the mTOR/autophagy pathway predicts cognitive performance in APP/PS1 mice
- (2019) Rasika S. Vartak et al. NEUROBIOLOGY OF AGING
- Effect of melatonin on Aβ42 induced changes in the mitochondrial function related to Alzheimer’s disease in Drosophila melanogaster
- (2019) Rehana Khatoon et al. NEUROSCIENCE LETTERS
- Impairment of Macroautophagy in Dopamine Neurons Has Opposing Effects on Parkinsonian Pathology and Behavior
- (2019) Benjamin H.M. Hunn et al. Cell Reports
- Heparan Sulfate Structure Affects Autophagy, Lifespan, Responses to Oxidative Stress, and Cell Degeneration inDrosophila parkin Mutants
- (2019) Claire Reynolds-Peterson et al. G3-Genes Genomes Genetics
- Beclin 1 deficiency causes hepatic cell apoptosis via endoplasmic reticulum stress in zebrafish larvae
- (2019) Guoping Dong et al. FEBS LETTERS
- Stress granule mediated protein aggregation and underlying gene defects in the FTD-ALS spectrum
- (2019) Yalda Baradaran-Heravi et al. NEUROBIOLOGY OF DISEASE
- Huntington’s Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy
- (2019) Leora M. Fox et al. NEURON
- Melatonin exerts neuroprotective effects by attenuating astro- and microgliosis and suppressing inflammatory response following spinal cord injury
- (2019) Zhijie Yang et al. NEUROPEPTIDES
- Interaction of melatonin and Bmal1 in the regulation of PI3K/AKT pathway components and cellular survival
- (2019) Mustafa C. Beker et al. Scientific Reports
- ATG3, a Target of miR-431-5p, Promotes Proliferation and Invasion of Colon Cancer via Promoting Autophagy
- (2019) Wei Huang et al. Cancer Management and Research
- Ganoderma lucidum extract ameliorates MPTP-induced parkinsonism and protects dopaminergic neurons from oxidative stress via regulating mitochondrial function, autophagy, and apoptosis
- (2018) Zhi-li Ren et al. ACTA PHARMACOLOGICA SINICA
- Piperlongumine restores the balance of autophagy and apoptosis by increasing BCL2 phosphorylation in rotenone-induced Parkinson disease models
- (2018) Jia Liu et al. Autophagy
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Huntington's disease: From basic science to therapeutics
- (2018) Carlos Cepeda et al. CNS Neuroscience & Therapeutics
- Pramipexole reduces soluble mutant huntingtin and protects striatal neurons through dopamine D3 receptors in a genetic model of Huntington's disease
- (2018) Diego Luis-Ravelo et al. EXPERIMENTAL NEUROLOGY
- mTOR in Down syndrome: Role in Aß and tau neuropathology and transition to Alzheimer disease-like dementia
- (2018) Fabio Di Domenico et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondria: Central Organelles for Melatonin′s Antioxidant and Anti-Aging Actions
- (2018) Russel Reiter et al. MOLECULES
- Mechanism and medical implications of mammalian autophagy
- (2018) Ivan Dikic et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanism of parkin activation by phosphorylation
- (2018) Véronique Sauvé et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Genetically reducing mTOR signaling rescues central insulin dysregulation in a mouse model of Alzheimer's disease
- (2018) Antonella Caccamo et al. NEUROBIOLOGY OF AGING
- Autophagy-related (ATG) 11, ATG9 and the phosphatidylinositol 3-kinase control ATG2-mediated formation of autophagosomes in Arabidopsis
- (2018) Sangwoo Kang et al. PLANT CELL REPORTS
- Ryanodine Receptors in Autophagy: Implications for Neurodegenerative Diseases?
- (2018) Tim Vervliet Frontiers in Cellular Neuroscience
- Oxidation of Atg3 and Atg7 mediates inhibition of autophagy
- (2018) Karen Frudd et al. Nature Communications
- Mechanism of parkin activation by phosphorylation
- (2018) Véronique Sauvé et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Activation of Neuregulin 1/ErbB Signaling Is Involved in the Development of TOCP-Induced Delayed Neuropathy
- (2018) Hai-Yang Xu et al. Frontiers in Molecular Neuroscience
- Dysfunction of Optineurin in Amyotrophic Lateral Sclerosis and Glaucoma
- (2018) Reka P. Toth et al. Frontiers in Immunology
- Melatonin and inflammation - story of a double-edged blade
- (2018) Rüdiger Hardeland JOURNAL OF PINEAL RESEARCH
- Structures of filaments from Pick’s disease reveal a novel tau protein fold
- (2018) Benjamin Falcon et al. NATURE
- Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases
- (2018) Claudio Soto et al. NATURE NEUROSCIENCE
- Differential Effects of Autophagy-Related 10 Protein on HCV Replication and Autophagy Flux Are Mediated by Its Cysteine44 and Cysteine135
- (2018) Miao-Qing Zhang et al. Frontiers in Immunology
- Early intrathecal infusion of everolimus restores cognitive function and mood in a murine model of Alzheimer's disease
- (2018) Tommaso Cassano et al. EXPERIMENTAL NEUROLOGY
- Intracellular metalloprotease activity controls intraneuronal Aβ aggregation and limits secretion of Aβ via exosomes
- (2018) Javier Pacheco-Quinto et al. FASEB JOURNAL
- The multiple protective roles and molecular mechanisms of melatonin and its precursor N-acetylserotonin in targeting brain injury and liver damage and in maintaining bone health
- (2018) Chengliang Luo et al. FREE RADICAL BIOLOGY AND MEDICINE
- Genetic suppression of collapsin response mediator protein 2 phosphorylation improves outcome in methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson’s model mice
- (2018) Kentaro Togashi et al. GENES TO CELLS
- Melatonin Influences Structural Plasticity in the Axons of Granule Cells in the Dentate Gyrus of Balb/C Mice
- (2018) Gerardo Ramírez-Rodríguez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration
- (2018) Gregor Bieri et al. Molecular Neurodegeneration
- Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson’s disease
- (2018) Tae-In Kam et al. SCIENCE
- ZZ-dependent regulation of p62/SQSTM1 in autophagy
- (2018) Yi Zhang et al. Nature Communications
- The mammalian ULK1 complex and autophagy initiation
- (2017) Maria Zachari et al. Essays in Biochemistry
- Pathogenic commonalities between spinal muscular atrophy and amyotrophic lateral sclerosis: Converging roads to therapeutic development
- (2017) Melissa Bowerman et al. European Journal of Medical Genetics
- Neferine augments therapeutic efficacy of cisplatin through ROS- mediated non-canonical autophagy in human lung adenocarcinoma (A549 cells)
- (2017) Sivalingam Kalai Selvi et al. FOOD AND CHEMICAL TOXICOLOGY
- Autophagy Roles in the Modulation of DNA Repair Pathways
- (2017) Luciana Gomes et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Autophagy-regulating protease Atg4: structure, function, regulation and inhibition
- (2017) Tatsuro Maruyama et al. JOURNAL OF ANTIBIOTICS
- Autophagy: The spotlight for cellular stress responses
- (2017) Palaniyandi Ravanan et al. LIFE SCIENCES
- Autophagy Receptors and Neurodegenerative Diseases
- (2017) Zhiqiang Deng et al. TRENDS IN CELL BIOLOGY
- Huntington’s disease: of mice and men
- (2017) Emma Yhnell Oncotarget
- DJ-1 Inhibits α-Synuclein Aggregation by Regulating Chaperone-Mediated Autophagy
- (2017) Chuan-Ying Xu et al. Frontiers in Aging Neuroscience
- Amyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms
- (2017) Martin Madill et al. Molecular Brain
- Parkin deficiency exacerbate ethanol-induced dopaminergic neurodegeneration by P38 pathway dependent inhibition of autophagy and mitochondrial function
- (2017) Chul Ju Hwang et al. Redox Biology
- Neuronal Cell Death and Degeneration through Increased Nitroxidative Stress and Tau Phosphorylation in HIV-1 Transgenic Rats
- (2017) Young-Eun Cho et al. PLoS One
- Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies
- (2016) Giuseppa Pistritto et al. Aging-US
- Enhanced autophagy as a potential mechanism for the improved physiological function by simvastatin in muscular dystrophy
- (2016) Nicholas P. Whitehead Autophagy
- Neferine prevents autophagy induced by hypoxia through activation of Akt/mTOR pathway and Nrf2 in muscle cells
- (2016) Rathinasamy Baskaran et al. BIOMEDICINE & PHARMACOTHERAPY
- Does any drug to treat cancer target mTOR and iron hemostasis in neurodegenerative disorders?
- (2016) Mohammad Jodeiri Farshbaf et al. BIOMETALS
- Mitochondrial dysfunction and cell death in neurodegenerative diseases through nitroxidative stress
- (2016) Mohammed Akbar et al. BRAIN RESEARCH
- Autophagy in the CNS and Periphery Coordinate Lipophagy and Lipolysis in the Brown Adipose Tissue and Liver
- (2016) Nuria Martinez-Lopez et al. Cell Metabolism
- Glutamate Excitotoxicity and Oxidative Stress in Epilepsy: Modulatory Role of Melatonin
- (2016) Shruti Vishnoi et al. JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY
- Regulation of autophagy by Beclin 1 in the heart
- (2016) Yasuhiro Maejima et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Mechanisms of Selective Autophagy in Normal Physiology and Cancer
- (2016) Joseph D. Mancias et al. JOURNAL OF MOLECULAR BIOLOGY
- Melatonin alleviates postinfarction cardiac remodeling and dysfunction by inhibiting Mst1
- (2016) Jianqiang Hu et al. JOURNAL OF PINEAL RESEARCH
- Parkinson's disease
- (2016) Richard Barnett LANCET
- Trehalose rescues glial cell dysfunction in striatal cultures from HD R6/1 mice at early postnatal development
- (2016) Juan Perucho et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- TRPM2 Promotes Neurotoxin MPP+/MPTP-Induced Cell Death
- (2016) Yuyang Sun et al. MOLECULAR NEUROBIOLOGY
- ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington’s disease models
- (2016) Mitchell S. Wold et al. Molecular Neurodegeneration
- Parkinson's disease
- (2016) Michelle Grayson NATURE
- Neurodegenerative diseases
- (2016) Marie-Thérèse Heemels NATURE
- Level of PICALM, a key component of clathrin-mediated endocytosis, is correlated with levels of phosphotau and autophagy-related proteins and is associated with tau inclusions in AD, PSP and Pick disease
- (2016) Kunie Ando et al. NEUROBIOLOGY OF DISEASE
- Activation of AMPK-induced autophagy ameliorates Huntington disease pathology in vitro
- (2016) Carolin Walter et al. NEUROPHARMACOLOGY
- Serine 403-phosphorylated p62/SQSTM1 immunoreactivity in inclusions of neurodegenerative diseases
- (2016) Masaru Kurosawa et al. NEUROSCIENCE RESEARCH
- Melatoninergic System in Parkinson’s Disease: From Neuroprotection to the Management of Motor and Nonmotor Symptoms
- (2016) Josiel Mileno Mack et al. Oxidative Medicine and Cellular Longevity
- Ubiquitin-Dependent And Independent Signals In Selective Autophagy
- (2016) Aliaksandr Khaminets et al. TRENDS IN CELL BIOLOGY
- α-Synuclein-Based Animal Models of Parkinson's Disease: Challenges and Opportunities in a New Era
- (2016) Naomi P. Visanji et al. TRENDS IN NEUROSCIENCES
- Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation
- (2015) Ling-Yan Su et al. Autophagy
- GBA deficiency promotes SNCA/α-synuclein accumulation through autophagic inhibition by inactivated PPP2A
- (2015) Ting-Ting Du et al. Autophagy
- A large-scale analysis of autophagy-related gene expression identifies new regulators of autophagy
- (2015) Amélie Bernard et al. Autophagy
- Progressive endolysosomal deficits impair autophagic clearance beginning at early asymptomatic stages in fALS mice
- (2015) Yuxiang Xie et al. Autophagy
- Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism
- (2015) Wen-Chuan Shen et al. Autophagy
- Choose Delicately and Reuse Adequately: The Newly Revealed Process of Autophagy
- (2015) Satoru Kobayashi BIOLOGICAL & PHARMACEUTICAL BULLETIN
- LAMP proteins account for the maturation delay during the establishment of theCoxiella burnetii-containing vacuole
- (2015) Jan Schulze-Luehrmann et al. CELLULAR MICROBIOLOGY
- Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer’s Disease
- (2015) Robert Baranello et al. Current Alzheimer Research
- Unc-51 like kinase 1 (ULK1) in silico analysis for biomarker identification: A vital component of autophagy
- (2015) Rohit Randhawa et al. GENE
- Autophagy and neurodegeneration
- (2015) Rebecca A. Frake et al. JOURNAL OF CLINICAL INVESTIGATION
- Parkin cooperates with GDNF/RET signaling to prevent dopaminergic neuron degeneration
- (2015) Durga Praveen Meka et al. JOURNAL OF CLINICAL INVESTIGATION
- mTOR: a pharmacologic target for autophagy regulation
- (2015) Young Chul Kim et al. JOURNAL OF CLINICAL INVESTIGATION
- Melatonin regulates the autophagic flux via activation of alpha-7 nicotinic acetylcholine receptors
- (2015) Jae-Kyo Jeong et al. JOURNAL OF PINEAL RESEARCH
- Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis
- (2015) Anna Fernández et al. JOURNAL OF PINEAL RESEARCH
- Melatonin attenuates impairments of structural hippocampal neuroplasticity in OXYS rats during active progression of Alzheimer's disease-like pathology
- (2015) Natalia A. Stefanova et al. JOURNAL OF PINEAL RESEARCH
- Live to die another way: modes of programmed cell death and the signals emanating from dying cells
- (2015) Yaron Fuchs et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The different roles of selective autophagic protein degradation in mammalian cells
- (2015) Da-wei Wang et al. Oncotarget
- Effects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculation
- (2015) Mustafa C. Beker et al. Oncotarget
- Therapeutic Effect of Berberine on Huntington’s Disease Transgenic Mouse Model
- (2015) Wenxiao Jiang et al. PLoS One
- NDP52 associates with phosphorylated tau in brains of an Alzheimer disease mouse model
- (2014) Sunhyo Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Interaction of Grb2 SH3 domain with UVRAG in an Alzheimer’s disease–like scenario
- (2014) Kasturi Roy et al. Biochemistry and Cell Biology
- Autophagy in the physiology and pathology of the central nervous system
- (2014) V Nikoletopoulou et al. CELL DEATH AND DIFFERENTIATION
- The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration
- (2014) David Heras-Sandoval et al. CELLULAR SIGNALLING
- Selective clearance of aberrant tau proteins and rescue of neurotoxicity by transcription factor EB
- (2014) V. A. Polito et al. EMBO Molecular Medicine
- Melatonin Regulates Aging and Neurodegeneration through Energy Metabolism, Epigenetics, Autophagy and Circadian Rhythm Pathways
- (2014) Anorut Jenwitheesuk et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- N-Acetyl-Serotonin Offers Neuroprotection through Inhibiting Mitochondrial Death Pathways and Autophagic Activation in Experimental Models of Ischemic Injury
- (2014) H. Zhou et al. JOURNAL OF NEUROSCIENCE
- Induction of autophagy in human neuroblastoma SH-SY5Y cells by tri-ortho-cresyl phosphate
- (2014) Ding-Xin Long et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Genetic deletion of MT1/MT2 melatonin receptors enhances murine cognitive and motor performance
- (2014) G. O’Neal-Moffitt et al. NEUROSCIENCE
- PICALM modulates autophagy activity and tau accumulation
- (2014) Kevin Moreau et al. Nature Communications
- Phosphorylation of serine 349 of p62 in Alzheimer’s disease brain
- (2014) Kunikazu Tanji et al. Acta Neuropathologica Communications
- An Overview of Autophagy: Morphology, Mechanism, and Regulation
- (2013) Katherine R. Parzych et al. ANTIOXIDANTS & REDOX SIGNALING
- Structures of Atg7-Atg3 and Atg7-Atg10 reveal noncanonical mechanisms of E2 recruitment by the autophagy E1
- (2013) Stephen E. Kaiser et al. Autophagy
- Therapeutic neuroprotective agents for amyotrophic lateral sclerosis
- (2013) Rachna S. Pandya et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Rhes, a Striatal-selective Protein Implicated in Huntington Disease, Binds Beclin-1 and Activates Autophagy
- (2013) Robert G. Mealer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Distinguishing between apoptosis, necrosis, necroptosis and other cell death modalities
- (2013) Seamus J. Martin et al. METHODS
- Lysosomal integral membrane protein-2: A new player in lysosome-related pathology
- (2013) Ashley Gonzalez et al. MOLECULAR GENETICS AND METABOLISM
- Autophagosomes form at ER–mitochondria contact sites
- (2013) Maho Hamasaki et al. NATURE
- Emerging regulation and functions of autophagy
- (2013) Patricia Boya et al. NATURE CELL BIOLOGY
- Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis
- (2013) Yi Zhang et al. NEUROBIOLOGY OF DISEASE
- Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer’s Disease
- (2013) Kurt M. Lucin et al. NEURON
- Induction of autophagy by TOCP in differentiated human neuroblastoma cells lead to degradation of cytoskeletal components and inhibition of neurite outgrowth
- (2013) Jia-Xiang Chen et al. TOXICOLOGY
- Autophagy is a protective response to ethanol neurotoxicity
- (2012) Gang Chen et al. Autophagy
- The role of ALFY in selective autophagy
- (2012) P Isakson et al. CELL DEATH AND DIFFERENTIATION
- Calcium-dependent neutral cysteine protease and organophosphate-induced delayed neuropathy
- (2012) Fuyong Song et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Mechanisms for consideration for intervention in the development of organophosphorus-induced delayed neuropathy
- (2012) Guilherme L. Emerick et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity
- (2012) Jae-Kyo Jeong et al. JOURNAL OF PINEAL RESEARCH
- SUMO routes ribosome maturation
- (2012) Elisabeth Finkbeiner et al. Nucleus
- Regulation of the Autophagic Bcl-2/Beclin 1 Interaction
- (2012) Jean-Paul Decuypere et al. Cells
- PARP and RIP 1 are required for autophagy induced by 11'-deoxyverticillin A, which precedes caspase-dependent apoptosis
- (2011) Nan Zhang et al. Autophagy
- The unfolded protein response and proteostasis in Alzheimer disease
- (2011) Wiep Scheper et al. Autophagy
- Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
- (2011) Jisun Lee et al. BIOCHEMICAL JOURNAL
- The Melatonin MT1 Receptor Axis Modulates Mutant Huntingtin-Mediated Toxicity
- (2011) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Melatonin treatment restores mitochondrial function in Alzheimer’s mice: a mitochondrial protective role of melatonin membrane receptor signaling
- (2011) Natasa Dragicevic et al. JOURNAL OF PINEAL RESEARCH
- Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α-synuclein aggregation
- (2011) Chia-Fu Chang et al. JOURNAL OF PINEAL RESEARCH
- Melatonin protects against rotenone-induced cell injury via inhibition of Omi and Bax-mediated autophagy in Hela cells
- (2011) Hongyan Zhou et al. JOURNAL OF PINEAL RESEARCH
- Melatonin as a Neuroprotective Agent in the Rodent Models of Parkinson’s Disease: Is it All Set to Irrefutable Clinical Translation?
- (2011) Naveen Kumar Singhal et al. MOLECULAR NEUROBIOLOGY
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- Early differential cell death and survival mechanisms initiate and contribute to the development of OPIDN: A study of molecular, cellular, and anatomical parameters
- (2011) T.V. Damodaran et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
- (2010) Ashley R. Winslow et al. JOURNAL OF CELL BIOLOGY
- Review Article: Genetics of Alzheimer Disease
- (2010) Lynn M. Bekris et al. JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
- The mechanism for the neuroprotective effect of melatonin against methamphetamine-induced autophagy
- (2010) Chutikorn Nopparat et al. JOURNAL OF PINEAL RESEARCH
- Signaling pathways in mitochondrial dysfunction and aging
- (2010) Cristina Mammucari et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
- (2010) Marta Martinez-Vicente et al. NATURE NEUROSCIENCE
- Mechanism of amyloid plaque formation suggests an intracellular basis of A pathogenicity
- (2010) R. P. Friedrich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of autophagy by ROS: physiology and pathology
- (2010) Ruth Scherz-Shouval et al. TRENDS IN BIOCHEMICAL SCIENCES
- Reduced IGF-1 Signaling Delays Age-Associated Proteotoxicity in Mice
- (2009) Ehud Cohen et al. CELL
- Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy
- (2009) Paul Nicklin et al. CELL
- The Antiapoptotic Activity of Melatonin in Neurodegenerative Diseases
- (2009) Xin Wang CNS Neuroscience & Therapeutics
- Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model
- (2009) Victor Tapias et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease
- (2009) James M. Olcese et al. JOURNAL OF PINEAL RESEARCH
- Prion-like mechanisms in neurodegenerative diseases
- (2009) Bess Frost et al. NATURE REVIEWS NEUROSCIENCE
- Methazolamide and Melatonin Inhibit Mitochondrial Cytochrome C Release and Are Neuroprotective in Experimental Models of Ischemic Injury
- (2009) Xin Wang et al. STROKE
- The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases
- (2008) Konstanze F Winklhofer et al. EMBO JOURNAL
- Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series
- (2008) Fumiyo Ikeda et al. EMBO REPORTS
- Melatonin attenuates methamphetamine-induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK-N-SH cells
- (2008) Patthara Kongsuphol et al. JOURNAL OF PINEAL RESEARCH
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
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