标题
Molecular Mechanisms and Emerging Therapeutics for Osteoporosis
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 20, Pages 7623
出版商
MDPI AG
发表日期
2020-10-15
DOI
10.3390/ijms21207623
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Unraveling: Cardiac and Musculoskeletal Defects and their Role in Common Alzheimer disease Morbidity and Mortality
- (2020) Vidyani Suryadevara et al. AMERICAN JOURNAL OF PATHOLOGY
- At the Crossroads of the Adipocyte and Osteoclast Differentiation Programs: Future Therapeutic Perspectives
- (2020) Shanmugam Muruganandan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pathogenesis of glucocorticoid-induced osteoporosis and options for treatment
- (2020) Pojchong Chotiyarnwong et al. Nature Reviews Endocrinology
- Pros and Cons of Denosumab Treatment for Osteoporosis and Implication for RANKL Aptamer Therapy
- (2020) Ning Zhang et al. Frontiers in Cell and Developmental Biology
- Prospect of Stem Cell Therapy and Regenerative Medicine in Osteoporosis
- (2020) Babak Arjmand et al. Frontiers in Endocrinology
- RANKL/RANK/OPG system beyond bone remodeling: involvement in breast cancer and clinical perspectives
- (2019) Marco Infante et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Osteoporosis
- (2019) Juliet E Compston et al. LANCET
- Unveiling Mesenchymal Stromal Cells’ Organizing Function in Regeneration
- (2019) Peter Nimiritsky et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Development and validation of Alzheimer’s Disease Animal Model for the Purpose of Regenerative Medicine
- (2019) Parisa Goodarzi et al. CELL AND TISSUE BANKING
- Molecular-Based Treatment Strategies for Osteoporosis: A Literature Review
- (2019) Yuichiro Ukon et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- FDA approves first-in-class osteoporosis drug
- (2019) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Inhibition of Osteoclastogenesis by Thioredoxin-Interacting Protein-Derived Peptide (TN13)
- (2019) Mi Kim et al. Journal of Clinical Medicine
- Anti-Osteoporotic Effects of Kukoamine B Isolated from Lycii Radicis Cortex Extract on Osteoblast and Osteoclast Cells and Ovariectomized Osteoporosis Model Mice
- (2019) Eunkuk Park et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Petunidin, a B-ring 5′-O-Methylated Derivative of Delphinidin, Stimulates Osteoblastogenesis and Reduces sRANKL-Induced Bone Loss
- (2019) Masahiro Nagaoka et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Stem cells in Osteoporosis: From Biology to New Therapeutic Approaches
- (2019) Vasilis Paspaliaris et al. Stem Cells International
- Glucosylceramide synthase regulates adipo‐osteogenic differentiation through synergistic activation of PPARγ with GlcCer
- (2019) Hyun‐Jun Jang et al. FASEB JOURNAL
- A road map for understanding molecular and genetic determinants of osteoporosis
- (2019) Tie-Lin Yang et al. Nature Reviews Endocrinology
- Effects of single or combination therapy of teriparatide and anti-RANKL monoclonal antibody on bone defect regeneration in mice
- (2018) Kazuma Kitaguchi et al. BONE
- Underlying Signaling Pathways and Therapeutic Applications of Pulsed Electromagnetic Fields in Bone Repair
- (2018) Jie Yuan et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Targeting sphingosine-1-phosphate lyase as an anabolic therapy for bone loss
- (2018) Sarah Weske et al. NATURE MEDICINE
- Denosumab versus risedronate in glucocorticoid-induced osteoporosis: a multicentre, randomised, double-blind, active-controlled, double-dummy, non-inferiority study
- (2018) Kenneth G Saag et al. Lancet Diabetes & Endocrinology
- Mesenchymal Stem Cell Migration during Bone Formation and Bone Diseases Therapy
- (2018) Peihong Su et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Advances in Regenerative Medicine and Tissue Engineering: Innovation and Transformation of Medicine
- (2018) Kevin Dzobo et al. Stem Cells International
- The effect of PPARγ inhibition on bone marrow adipose tissue and bone in C3H/HeJ mice
- (2018) Kerensa M. Beekman et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Extracellular vesicle and mesenchymal stem cells in bone regeneration: recent progress and perspectives
- (2018) Chenyu Chu et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Prospect of mesenchymal stem cells in therapy of osteoporosis: A review
- (2018) Leili Aghebati-Maleki et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Osteoblast autophagy in glucocorticoid-induced osteoporosis
- (2018) Lufei Wang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- An atlas of genetic influences on osteoporosis in humans and mice
- (2018) John A. Morris et al. NATURE GENETICS
- Combination therapy with parathyroid hormone analogs and antiresorptive agents for osteoporosis: a systematic review and meta-analysis of randomized controlled trials
- (2018) S. Lou et al. OSTEOPOROSIS INTERNATIONAL
- Romosozumab (sclerostin monoclonal antibody) versus teriparatide in postmenopausal women with osteoporosis transitioning from oral bisphosphonate therapy: a randomised, open-label, phase 3 trial
- (2017) Bente L Langdahl et al. LANCET
- Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis
- (2017) Kenneth G. Saag et al. NEW ENGLAND JOURNAL OF MEDICINE
- The RANK/RANKL/OPG system in tumorigenesis and metastasis of cancer stem cell: potential targets for anticancer therapy
- (2017) Mekonnen Sisay et al. OncoTargets and Therapy
- Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway
- (2017) Mengrui Wu et al. Nature Communications
- 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis
- (2017) Lenore Buckley et al. Arthritis & Rheumatology
- Using Osteoporosis Therapies in Combination
- (2017) Michael R. McClung Current Osteoporosis Reports
- Strontium-loaded titania nanotube arrays repress osteoclast differentiation through multiple signalling pathways: In vitro and in vivo studies
- (2017) Baoguo Mi et al. Scientific Reports
- p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner
- (2017) Qian Cong et al. Scientific Reports
- Iron overload inhibits osteogenic commitment and differentiation of mesenchymal stem cells via the induction of ferritin
- (2016) Enikő Balogh et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Osteoporosis: the current status of mesenchymal stem cell-based therapy
- (2016) Jitrada Phetfong et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Influences of teriparatide administration on marrow fat content in postmenopausal osteopenic women using MR spectroscopy
- (2016) Y. Yang et al. CLIMACTERIC
- Binding Selectivity of Abaloparatide for PTH-Type-1-Receptor Conformations and Effects on Downstream Signaling
- (2016) Gary Hattersley et al. ENDOCRINOLOGY
- Effect of Abaloparatide vs Placebo on New Vertebral Fractures in Postmenopausal Women With Osteoporosis
- (2016) Paul D. Miller et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption
- (2016) Jian Luo et al. NATURE MEDICINE
- Aptamers as targeted therapeutics: current potential and challenges
- (2016) Jiehua Zhou et al. NATURE REVIEWS DRUG DISCOVERY
- Romosozumab Treatment in Postmenopausal Women with Osteoporosis
- (2016) Felicia Cosman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Comparative efficacy of bisphosphonates in short-term fracture prevention for primary osteoporosis: a systematic review with network meta-analyses
- (2016) J. Zhou et al. OSTEOPOROSIS INTERNATIONAL
- Glucocorticoid-induced Osteoporosis
- (2016) Xena Whittier et al. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
- Chemokine-Like Receptor 1 Is a Novel Wnt Target Gene that Regulates Mesenchymal Stem Cell Differentiation
- (2016) Shanmugam Muruganandan et al. STEM CELLS
- Thioredoxin-interacting protein regulates haematopoietic stem cell ageing and rejuvenation by inhibiting p38 kinase activity
- (2016) Haiyoung Jung et al. Nature Communications
- Monthly High-Dose Vitamin D Treatment for the Prevention of Functional Decline
- (2016) Heike A. Bischoff-Ferrari et al. JAMA Internal Medicine
- Effect of Stem Cell Therapy on Bone Mineral Density: A Meta-Analysis of Preclinical Studies in Animal Models of Osteoporosis
- (2016) Feng Li et al. PLoS One
- Short-term and long-term effects of osteoporosis therapies
- (2015) Ian R. Reid Nature Reviews Endocrinology
- CB2 and TRPV1 receptors oppositely modulate in vitro human osteoblast activity
- (2015) Francesca Rossi et al. PHARMACOLOGICAL RESEARCH
- Mechanisms of Bone Resorption in Periodontitis
- (2015) Stefan A. Hienz et al. Journal of Immunology Research
- Comparative Effectiveness of Pharmacologic Treatments to Prevent Fractures
- (2014) Carolyn J. Crandall et al. ANNALS OF INTERNAL MEDICINE
- Adipose-derived stem cells alleviate osteoporosis by enchancing osteogenesis and inhibiting adipogenesis in a rabbit model
- (2014) Xinhai Ye et al. CYTOTHERAPY
- The RUNX2 Cistrome in Osteoblasts
- (2014) Mark B. Meyer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Age-related Marrow Adipogenesis Is Linked to Increased Expression of RANKL
- (2014) Sunao Takeshita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Recent Prevalence of Osteoporosis and Low Bone Mass in the United States Based on Bone Mineral Density at the Femoral Neck or Lumbar Spine
- (2014) Nicole C Wright et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Clinician’s Guide to Prevention and Treatment of Osteoporosis
- (2014) F. Cosman et al. OSTEOPOROSIS INTERNATIONAL
- Deregulation of Bone Forming Cells in Bone Diseases and Anabolic Effects of Strontium-Containing Agents and Biomaterials
- (2014) Shuang Tan et al. Biomed Research International
- Biology of the RANKL–RANK–OPG System in Immunity, Bone, and Beyond
- (2014) Matthew C. Walsh et al. Frontiers in Immunology
- PTEN regulation by the Akt/GSK-3β axis during RANKL signaling
- (2013) Hyun Duk Jang et al. BONE
- The Interplay between the Bone and the Immune System
- (2013) Giorgio Mori et al. Clinical & Developmental Immunology
- The Osteocyte: An Endocrine Cell … and More
- (2013) Sarah L. Dallas et al. ENDOCRINE REVIEWS
- The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine
- (2013) Paolo Bianco et al. NATURE MEDICINE
- Chemerin neutralization blocks hematopoietic stem cell osteoclastogenesis
- (2013) Shanmugam Muruganandan et al. STEM CELLS
- Combination of Tumor Necrosis Factor α and Interleukin-6 Induces Mouse Osteoclast-like Cells With Bone Resorption Activity Both In Vitro and In Vivo
- (2013) Kazuhiro Yokota et al. Arthritis & Rheumatology
- Osteoclasts: New Insights
- (2013) Feng Xu et al. Bone Research
- The effect of diminished osteogenic signals on reduced osteoporosis recovery in aged mice and the potential therapeutic use of adipose-derived stem cells
- (2012) Hen-Yu Liu et al. BIOMATERIALS
- Umbilical cord blood stem cells: clinical trials in non-hematological disorders
- (2012) Dusko Ilic et al. BRITISH MEDICAL BULLETIN
- Signaling Networks that Control the Lineage Commitment and Differentiation of Bone Cells
- (2012) Carrie S. Soltanoff et al. CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
- Comparison of clinical efficacy and safety between denosumab and alendronate in postmenopausal women with osteoporosis: a meta-analysis
- (2012) T. Lin et al. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
- Denosumab: mechanism of action and clinical outcomes
- (2012) D. A. Hanley et al. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
- Immune Regulation of Osteoclast Function in Postmenopausal Osteoporosis: A Critical Interdisciplinary Perspective
- (2012) Renqing Zhao International Journal of Medical Sciences
- Acetylcholinesterase inhibitors and the risk of hip fracture in Alzheimer's disease patients: A case-control study
- (2012) Iskandar Tamimi et al. JOURNAL OF BONE AND MINERAL RESEARCH
- A phase 3 trial of the efficacy and safety of oral recombinant calcitonin: The oral calcitonin in postmenopausal osteoporosis (ORACAL) trial
- (2012) Neil Binkley et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Osteoporosis in Men: An Endocrine Society Clinical Practice Guideline
- (2012) Nelson B. Watts et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Anti-Hyperalgesic Effects of Calcitonin on Neuropathic Pain Interacting with its Peripheral Receptors
- (2012) Akitoshi Ito et al. Molecular Pain
- Bench to bedside: elucidation of the OPG–RANK–RANKL pathway and the development of denosumab
- (2012) David L. Lacey et al. NATURE REVIEWS DRUG DISCOVERY
- Long-term treatment of osteoporosis: safety and efficacy appraisal of denosumab
- (2012) Athanasios Anastasilakis Therapeutics and Clinical Risk Management
- Intercellular Cross-Talk Among Bone Cells: New Factors and Pathways
- (2012) Natalie A. Sims et al. Current Osteoporosis Reports
- Role of cannabinoids in the regulation of bone remodeling
- (2012) Aymen I. Idris et al. Frontiers in Endocrinology
- Bisphosphonates: The first 40years
- (2011) R. Graham G. Russell BONE
- TAZ is required for the osteogenic and anti-adipogenic activities of kaempferol
- (2011) Mi Ran Byun et al. BONE
- Osteoclast Activity and Subtypes as a Function of Physiology and Pathology—Implications for Future Treatments of Osteoporosis
- (2011) K. Henriksen et al. ENDOCRINE REVIEWS
- Osteoblasts in osteoporosis: past, emerging, and future anabolic targets
- (2011) Pierre J Marie et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Proliferation and differentiation potential of human adipose-derived mesenchymal stem cells isolated from elderly patients with osteoporotic fractures
- (2011) Hui-Ting Chen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Integration of BMP, Wnt, and notch signaling pathways in osteoblast differentiation
- (2011) Grace L. Lin et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Akt Induces Osteoclast Differentiation through Regulating the GSK3 /NFATc1 Signaling Cascade
- (2011) J. B. Moon et al. JOURNAL OF IMMUNOLOGY
- Building strong bones: molecular regulation of the osteoblast lineage
- (2011) Fanxin Long NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Prevalence of long-term oral glucocorticoid prescriptions in the UK over the past 20 years
- (2011) L. Fardet et al. RHEUMATOLOGY
- Clinical Efficacy and Safety of Denosumab in Postmenopausal Women with Low Bone Mineral Density and Osteoporosis: A Meta-Analysis
- (2011) Camilla von Keyserlingk et al. SEMINARS IN ARTHRITIS AND RHEUMATISM
- Advances in Glucocorticoid-Induced Osteoporosis
- (2011) Debby den Uyl et al. Current Rheumatology Reports
- Bone loss caused by iron overload in a murine model: importance of oxidative stress
- (2010) J. Tsay et al. BLOOD
- Disruption of the Fgf2 gene activates the adipogenic and suppresses the osteogenic program in mesenchymal marrow stromal stem cells
- (2010) Liping Xiao et al. BONE
- PGC1β Mediates PPARγ Activation of Osteoclastogenesis and Rosiglitazone-Induced Bone Loss
- (2010) Wei Wei et al. Cell Metabolism
- Update on the Pharmacological Treatment of Alzheimers Disease
- (2010) Fadi Massoud et al. Current Neuropharmacology
- Annual High-Dose Oral Vitamin D and Falls and Fractures in Older Women
- (2010) Kerrie M. Sanders et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- High level of serum undercarboxylated osteocalcin in patients with incident fractures during bisphosphonate treatment
- (2010) Masataka Shiraki et al. JOURNAL OF BONE AND MINERAL METABOLISM
- Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone
- (2010) J.M. Hock et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The amazing osteocyte
- (2010) Lynda F Bonewald JOURNAL OF BONE AND MINERAL RESEARCH
- Third-Generation SERMs May Face Uphill Battle
- (2010) C. Schmidt JNCI-Journal of the National Cancer Institute
- Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study
- (2010) Roger MD Zebaze et al. LANCET
- Lasofoxifene in Postmenopausal Women with Osteoporosis
- (2010) Steven R. Cummings et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mortality rates after incident non-traumatic fractures in older men and women
- (2010) S. Morin et al. OSTEOPOROSIS INTERNATIONAL
- New knowledge on critical osteoclast formation and activation pathways from study of rare genetic diseases of osteoclasts: focus on the RANK/RANKL axis
- (2010) J. C. Crockett et al. OSTEOPOROSIS INTERNATIONAL
- The Aftermath of Hip Fracture: Discharge Placement, Functional Status Change, and Mortality
- (2009) S. E. Bentler et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Effects of teriparatide versus alendronate for treating glucocorticoid-induced osteoporosis: Thirty-six-month results of a randomized, double-blind, controlled trial
- (2009) Kenneth G. Saag et al. ARTHRITIS AND RHEUMATISM
- Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis
- (2009) Ben H. Mullin et al. BONE
- Cannabinoid Receptor Type 1 Protects against Age- Related Osteoporosis by Regulating Osteoblast and Adipocyte Differentiation in Marrow Stromal Cells
- (2009) Aymen I. Idris et al. Cell Metabolism
- Notch signaling enhances osteogenic differentiation while inhibiting adipogenesis in primary human bone marrow stromal cells
- (2009) Fernando Ugarte et al. EXPERIMENTAL HEMATOLOGY
- Short-term menatetrenone therapy increases gamma-carboxylation of osteocalcin with a moderate increase of bone turnover in postmenopausal osteoporosis: a randomized prospective study
- (2009) Masataka Shiraki et al. JOURNAL OF BONE AND MINERAL METABOLISM
- Zoledronic acid and risedronate in the prevention and treatment of glucocorticoid-induced osteoporosis (HORIZON): a multicentre, double-blind, double-dummy, randomised controlled trial
- (2009) David M Reid et al. LANCET
- TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation
- (2009) Yi Tang et al. NATURE MEDICINE
- Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis
- (2009) Steven R. Cummings et al. NEW ENGLAND JOURNAL OF MEDICINE
- Excess mortality following hip fracture: a systematic epidemiological review
- (2009) B. Abrahamsen et al. OSTEOPOROSIS INTERNATIONAL
- Identification of a Role for the ARHGEF3 Gene in Postmenopausal Osteoporosis
- (2008) Ben H. Mullin et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Systematic review of the benefits and harms of calcitriol and alfacalcidol for fractures and falls
- (2008) Siobhan O’Donnell et al. JOURNAL OF BONE AND MINERAL METABOLISM
- Bone Mineral Density Before and After Surgical Cure of Cushing’s Syndrome Due to Adrenocortical Adenoma: Prospective Study
- (2008) Akiko Kawamata et al. WORLD JOURNAL OF SURGERY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now