Microbiota tryptophan metabolism induces aryl hydrocarbon receptor activation and improves alcohol-induced liver injury

Associations between consumption of dietary fibers and the risk of cardiovascular diseases, cancers, type 2 diabetes, and mortality in the prospective NutriNet-Santé cohort

(2020) Valentin Partula et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Adherence to a plant-based, high-fibre dietary pattern is related to regression of non-alcoholic fatty liver disease in an elderly population

(2020) Louise J. M. Alferink et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Alcohol, liver disease and the gut microbiota

(2019) Jasmohan S. Bajaj   Nature Reviews Gastroenterology & Hepatology

Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogenesis in Mice

(2019) Jiong Yan et al.   GASTROENTEROLOGY

Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease

(2019) Yi Duan et al.   NATURE

Roseburia spp. Abundance Associates with Alcohol Consumption in Humans and Its Administration Ameliorates Alcoholic Fatty Liver in Mice

(2019) Boram Seo et al.   Cell Host & Microbe

Gut-liver axis alterations in alcoholic liver disease: Are bile acids the answer?

(2018) Jasmohan S. Bajaj et al.   HEPATOLOGY

Modulation of the intestinal bile acid/farnesoid X receptor/fibroblast growth factor 15 axis improves alcoholic liver disease in mice

(2018) Phillipp Hartmann et al.   HEPATOLOGY

Eating Patterns in Patients with Compensated Cirrhosis: A Case-Control Study

(2018) Camille Buscail et al.   Nutrients

Transplantation of human microbiota into conventional mice durably reshapes the gut microbiota

(2018) Laura Wrzosek et al.   Scientific Reports

Characterization of intestinal microbiota in alcoholic patients with and without alcoholic hepatitis or chronic alcoholic pancreatitis

(2018) Dragos Ciocan et al.   Scientific Reports

Bile acid homeostasis and intestinal dysbiosis in alcoholic hepatitis

(2018) Dragos Ciocan et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome

(2018) Jane M. Natividad et al.   Cell Metabolism

Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

(2018) Max G Griswold et al.   LANCET

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(2018) Helmut K. Seitz et al.   Nature Reviews Disease Primers

Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

(2018) Vishal Singh et al.   CELL

Bacteria engineered to produce IL-22 in intestine induce expression of REG3G to reduce ethanol-induced liver disease in mice

(2018) Tim Hendrikx et al.   GUT

Indole-3-Pyruvic Acid, an Aryl Hydrocarbon Receptor Activator, Suppresses Experimental Colitis in Mice

(2018) Reiji Aoki et al.   JOURNAL OF IMMUNOLOGY

Recovery of ethanol-inducedAkkermansia muciniphiladepletion ameliorates alcoholic liver disease

(2017) Christoph Grander et al.   GUT

Fecal microbiota manipulation prevents dysbiosis and alcohol-induced liver injury in mice

(2017) Gladys Ferrere et al.   JOURNAL OF HEPATOLOGY

Publisher Correction: Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus

(2017) Cristina Llorente et al.   Nature Communications

Lactobacillus reuteriincreases mucus thickness and ameliorates dextran sulphate sodium-induced colitis in mice

(2016) D. Ahl et al.   Acta Physiologica

Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation

(2016) Lirui Wang et al.   Cell Host & Microbe

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

(2016) Bruno Lamas et al.   NATURE MEDICINE

Lactobacillus rhamnosus GG supernatant promotes intestinal barrier function, balances T reg and T H 17 cells and ameliorates hepatic injury in a mouse model of chronic-binge alcohol feeding

(2016) Rui-Cong Chen et al.   TOXICOLOGY LETTERS

Supplementation of Saturated Long-Chain Fatty Acids Maintains Intestinal Eubiosis and Reduces Ethanol-induced Liver Injury in Mice

(2015) Peng Chen et al.   GASTROENTEROLOGY

Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease

(2015) M Llopis et al.   GUT

Dysbiosis-induced intestinal inflammation activates tumor necrosis factor receptor I and mediates alcoholic liver disease in mice

(2015) Peng Chen et al.   HEPATOLOGY

Social stress-enhanced severity of Citrobacter rodentium-induced colitis is CCL2-dependent and attenuated by probiotic Lactobacillus reuteri

(2015) A R Mackos et al.   Mucosal Immunology

Proteobacteria: microbial signature of dysbiosis in gut microbiota

(2015) Na-Ri Shin et al.   TRENDS IN BIOTECHNOLOGY

Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes

(2014) Xiaoting Wang et al.   NATURE

The Aryl Hydrocarbon Receptor: Differential Contribution to T Helper 17 and T Cytotoxic 17 Cell Development

(2014) Mark D. Hayes et al.   PLoS One

Deficiency of intestinal mucin-2 ameliorates experimental alcoholic liver disease in mice

(2013) Phillipp Hartmann et al.   HEPATOLOGY

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Lactobacillus rhamnosus GG reduces hepatic TNFα production and inflammation in chronic alcohol-induced liver injury

(2013) Yuhua Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

(2013) Morgan G I Langille et al.   NATURE BIOTECHNOLOGY

Metagenomic Analyses of Alcohol Induced Pathogenic Alterations in the Intestinal Microbiome and the Effect of Lactobacillus rhamnosus GG Treatment

(2013) Lara Bull-Otterson et al.   PLoS One

Chronic Alcohol Ingestion Increases Mortality and Organ Injury in a Murine Model of Septic Peritonitis

(2013) Benyam P. Yoseph et al.   PLoS One

Characterization of fecal microbial communities in patients with liver cirrhosis

(2011) Yanfei Chen et al.   HEPATOLOGY

AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

(2011) Jacob S Lee et al.   NATURE IMMUNOLOGY

Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3

(2010) Sung Hwan Ki et al.   HEPATOLOGY

Enteric dysbiosis associated with a mouse model of alcoholic liver disease

(2010) Arthur W. Yan et al.   HEPATOLOGY

Endotoxemia and gut barrier dysfunction in alcoholic liver disease

(2009) Radhakrishna Rao   HEPATOLOGY

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE