let-7 miRNAs inhibit CHD7 expression and control auditory-sensory progenitor cell behavior in the developing inner ear

Chromatin remodeler CHD7 regulates the stem cell identity of human neural progenitors

(2018) MuhChyi Chai et al.   GENES & DEVELOPMENT

Control of neural crest multipotency by Wnt signaling and the Lin28/let-7 axis

(2018) Debadrita Bhattacharya et al.   eLife

Chd7 Collaborates with Sox2 to Regulate Activation of Oligodendrocyte Precursor Cells after Spinal Cord Injury

(2017) Toru Doi et al.   JOURNAL OF NEUROSCIENCE

Sox2 in the differentiation of cochlear progenitor cells

(2016) Judith S. Kempfle et al.   Scientific Reports

Gene Transfer into the Chicken Auditory Organ by In Ovo Micro-electroporation

(2016) Lale Evsen et al.   Jove-Journal of Visualized Experiments

Lin28 promotes the proliferative capacity of neural progenitor cells in brain development

(2015) M. Yang et al.   DEVELOPMENT

Fgf10 is required for specification of non-sensory regions of the cochlear epithelium

(2015) Lisa D. Urness et al.   DEVELOPMENTAL BIOLOGY

Expression and Misexpression of the miR-183 Family in the Developing Hearing Organ of the Chicken

(2015) Kaidi D. Zhang et al.   PLoS One

SoxC transcription factors are essential for the development of the inner ear

(2015) Ksenia Gnedeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea

(2015) Erin J. Golden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved role of Sonic Hedgehog in tonotopic organization of the avian basilar papilla and mammalian cochlea

(2015) Eun Jin Son et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biogenesis and regulation of the let-7 miRNAs and their functional implications

(2015) Hosuk Lee et al.   Protein & Cell

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

Next-generation sequencing of small RNAs from inner ear sensory epithelium identifies microRNAs and defines regulatory pathways

(2014) Anya Rudnicki et al.   BMC GENOMICS

Hmga2 regulates self-renewal of retinal progenitors

(2014) S. Parameswaran et al.   DEVELOPMENT

Hey1 and Hey2 Control the Spatial and Temporal Pattern of Mammalian Auditory Hair Cell Differentiation Downstream of Hedgehog Signaling

(2014) A. Benito-Gonzalez et al.   JOURNAL OF NEUROSCIENCE

Effects of let-7b and TLX on the proliferation and differentiation of retinal progenitor cells in vitro

(2014) Ni Ni et al.   Scientific Reports

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding

(2013) Aleksandra Helwak et al.   CELL

The Long and Short of MicroRNA

(2013) Luke A. Yates et al.   CELL

The Chromatin Remodeler CHD7 Regulates Adult Neurogenesis via Activation of SoxC Transcription Factors

(2013) Weijun Feng et al.   Cell Stem Cell

Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea

(2013) T. Tateya et al.   DEVELOPMENT

Evolution and development of the tetrapod auditory system: an organ of Corti-centric perspective

(2013) Bernd Fritzsch et al.   EVOLUTION & DEVELOPMENT

Ectopic Expression of Activated Notch or SOX2 Reveals Similar and Unique Roles in the Development of the Sensory Cell Progenitors in the Mammalian Inner Ear

(2013) W. Pan et al.   JOURNAL OF NEUROSCIENCE

DIANA-microT web server v5.0: service integration into miRNA functional analysis workflows

(2013) Maria D. Paraskevopoulou et al.   NUCLEIC ACIDS RESEARCH

SOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors

(2013) F. Cimadamore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Auditory ganglion source of Sonic hedgehog regulates timing of cell cycle exit and differentiation of mammalian cochlear hair cells

(2013) Jinwoong Bok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt signaling during cochlear development

(2013) Vidhya Munnamalai et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties

(2013) Jinsuke Nishino et al.   eLife

Eya1-Six1 Interaction Is Sufficient to Induce Hair Cell Fate in the Cochlea by Activating Atoh1 Expression in Cooperation with Sox2

(2012) Mohi Ahmed et al.   DEVELOPMENTAL CELL

High-Throughput Functional MicroRNAs Profiling by Recombinant AAV-Based MicroRNA Sensor Arrays

(2012) Wenhong Tian et al.   PLoS One

The Prosensory Function of Sox2 in the Chicken Inner Ear Relies on the Direct Regulation of Atoh1

(2012) Joana Neves et al.   PLoS One

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure

(2011) Betsy R. Maller Schulman et al.   CELL CYCLE

Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: a mechanism for sensory organ specification

(2011) J. Neves et al.   DEVELOPMENT

Mature middle and inner ears express Chd7 and exhibit distinctive pathologies in a mouse model of CHARGE syndrome

(2011) Elizabeth A. Hurd et al.   HEARING RESEARCH

Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes

(2011) Erik Engelen et al.   NATURE GENETICS

The ATP-dependent chromatin remodeling enzyme CHD7 regulates pro-neural gene expression and neurogenesis in the inner ear

(2010) E. A. Hurd et al.   DEVELOPMENT

CHD7 cooperates with PBAF to control multipotent neural crest formation

(2010) Ruchi Bajpai et al.   NATURE

MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling

(2010) C. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear

(2010) W. Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA sponges: Progress and possibilities

(2010) M. S. Ebert et al.   RNA

CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell-Specific Gene Expression

(2010) Michael P. Schnetz et al.   PLoS Genetics

Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns

(2009) M. P. Schnetz et al.   GENOME RESEARCH

β-Catenin Up-regulatesAtoh1Expression in Neural Progenitor Cells by Interaction with anAtoh13′ Enhancer

(2009) Fuxin Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for Lin28 in primordial germ-cell development and germ-cell malignancy

(2009) Jason A. West et al.   NATURE

Hmga2 Promotes Neural Stem Cell Self-Renewal in Young but Not Old Mice by Reducing p16Ink4a and p19Arf Expression

(2008) Jinsuke Nishino et al.   CELL

Identification of Novel Regulators of atonal Expression in the Developing Drosophila Retina

(2008) D. Melicharek et al.   GENETICS

Determinants of MicroRNA Processing Inhibition by the Developmentally Regulated RNA-binding Protein Lin28

(2008) Elena Piskounova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Blockade of MicroRNA Processing by Lin28

(2008) S. R. Viswanathan et al.   SCIENCE

The let-7 family of microRNAs

(2008) Sarah Roush et al.   TRENDS IN CELL BIOLOGY