Mitochondrial apurinic/apyrimidinic endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma

Mitochondrial proteins: from biogenesis to functional networks

(2019) Nikolaus Pfanner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Serum AP-endonuclease 1 (sAPE1) as novel biomarker for hepatocellular carcinoma

(2019) Devis Pascut et al.   Oncotarget

The role of the N-terminal domain of human apurinic/apyrimidinic endonuclease 1, APE1, in DNA glycosylase stimulation

(2018) Olga A. Kladova et al.   DNA REPAIR

EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma

(2018) Peter R. Galle et al.   JOURNAL OF HEPATOLOGY

APE1: A skilled nucleic acid surgeon

(2018) Amy M. Whitaker et al.   DNA REPAIR

C3HeB/FeJ Mice mimic many aspects of gene expression and pathobiological features of human hepatocellular carcinoma

(2018) Jessica A. Zavadil et al.   MOLECULAR CARCINOGENESIS

Differential expression of APE1 in hepatocellular carcinoma and the effects on proliferation and apoptosis of cancer cells

(2018) Zhipeng Sun et al.   BioScience Trends

Apurinic/apyrimidinic endonuclease 1 (APE1/Ref-1) overexpression is an independent prognostic marker in prostate cancer without TMPRSS2:ERG fusion

(2017) Manuela Juhnke et al.   MOLECULAR CARCINOGENESIS

Human Apurinic/Apyrimidinic Endonuclease (APE1) Is Acetylated at DNA Damage Sites in Chromatin, and Acetylation Modulates Its DNA Repair Activity

(2016) Shrabasti Roychoudhury et al.   MOLECULAR AND CELLULAR BIOLOGY

Fast mitochondrial DNA isolation from mammalian cells for next-generation sequencing

(2016) Wilber Quispe-Tintaya et al.   BIOTECHNIQUES

High-Throughput Method for Automated Colony and Cell Counting by Digital Image Analysis Based on Edge Detection

(2016) Priya Choudhry   PLoS One

Targeting the DNA Damage Response in Cancer

(2015) Mark J. O’Connor   MOLECULAR CELL

Mitochondrial translocation of APE1 relies on the MIA pathway

(2015) A. Barchiesi et al.   NUCLEIC ACIDS RESEARCH

Lentiviral-mediated short hairpin RNA silencing of APE1 suppresses hepatocellular carcinoma proliferation and migration: A potential therapeutic target for hepatoma treatment

(2015) ZHI-HUA ZHENG et al.   ONCOLOGY REPORTS

Sustained proliferation in cancer: Mechanisms and novel therapeutic targets

(2015) Mark A. Feitelson et al.   SEMINARS IN CANCER BIOLOGY

EASL–EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma

(2015) et al.   JOURNAL OF HEPATOLOGY

Transcriptional Up-Regulation of APE1/Ref-1 in Hepatic Tumor: Role in Hepatocytes Resistance to Oxidative Stress and Apoptosis

(2015) Vittorio Di Maso et al.   PLoS One

Expression and Prognostic Significance of APE1/Ref-1 and NPM1 Proteins in High-Grade Ovarian Serous Cancer

(2014) Ambrogio P. Londero et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Induction of Apurinic Endonuclease 1 Overexpression by Endoplasmic Reticulum Stress in Hepatoma Cells

(2014) Tsung-Lin Cheng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Combined use of adenoviral vector Ad5/F35-mediated APE1 siRNA enhances the therapeutic efficacy of adenoviral-mediated p53 gene transfer in hepatoma cells in vitro and in vivo

(2013) YANPING CUN et al.   ONCOLOGY REPORTS

Silencing of APE1 Enhances Sensitivity of Human Hepatocellular Carcinoma Cells to Radiotherapy In Vitro and in a Xenograft Model

(2013) Yanping Cun et al.   PLoS One

Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells

(2012) Lisa Lirussi et al.   MOLECULAR BIOLOGY OF THE CELL

Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function

(2011) Carlo Vascotto et al.   MOLECULAR BIOLOGY OF THE CELL

Identification and Characterization of Mitochondrial Targeting Sequence of Human Apurinic/Apyrimidinic Endonuclease 1

(2010) Mengxia Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Report of a national conference on liver allocation in patients with hepatocellular carcinoma in the United States

(2009) Elizabeth A. Pomfret et al.   LIVER TRANSPLANTATION

Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells

(2009) Carlo Vascotto et al.   PROTEOMICS

The Many Functions of APE1/Ref-1: Not Only a DNA Repair Enzyme

(2008) Gianluca Tell et al.   ANTIOXIDANTS & REDOX SIGNALING