The Many Functions of APE1/Ref-1: Not Only a DNA Repair Enzyme

Role of the Multifunctional DNA Repair and Redox Signaling Protein Ape1/Ref-1 in Cancer and Endothelial Cells: Small-Molecule Inhibition of the Redox Function of Ape1

(2008) Meihua Luo et al.   ANTIOXIDANTS & REDOX SIGNALING

Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells

(2008) Muralidhar L Hegde et al.   CELL RESEARCH

APE1/Ref-1 regulates PTEN expression mediated by Egr-1

(2008) Damiano Fantini et al.   FREE RADICAL RESEARCH

Bcl2 Inhibits Abasic Site Repair by Down-regulating APE1 Endonuclease Activity

(2008) Jinfeng Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Granzyme K degrades the redox/DNA repair enzyme Ape1 to trigger oxidative stress of target cells leading to cytotoxicity

(2008) Yuming Guo et al.   MOLECULAR IMMUNOLOGY

Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease

(2008) M.M. Georgiadis et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage

(2008) A. Zaky et al.   NUCLEIC ACIDS RESEARCH

Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth

(2007) Melissa L. Fishel et al.   DNA REPAIR

Nuclear protein-induced bending and flexing of the hypoxic response element of the rat vascular endothelial growth factor promoter

(2007) Jeffrey F. Breit et al.   FASEB JOURNAL