Direct β‐ and γ‐C(sp 3 )−H Alkynylation of Free Carboxylic Acids

Distal γ‐C(sp3)−H Olefination of Ketone Derivatives and Free Carboxylic Acids

(2020) Han Seul Park et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ligand‐Enabled γ‐C(sp 3 )−H Olefination of Free Carboxylic Acids

(2020) Kiron Kumar Ghosh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ligand-Enabled Monoselective β-C(sp3)–H Acyloxylation of Free Carboxylic Acids Using a Practical Oxidant

(2020) Zhe Zhuang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric, Nearly Barrierless C(sp3)–H Activation Promoted by Easily-Accessible N-Protected Aminosulfoxides as New Chiral Ligands

(2019) Soufyan Jerhaoui et al.   ACS Catalysis

Pd(II)-Catalyzed Enantioselective Alkynylation of Unbiased Methylene C(sp3)–H Bonds Using 3,3′-Fluorinated-BINOL as a Chiral Ligand

(2019) Ye-Qiang Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Enabled Pd(II)-Catalyzed Iterative γ-C(sp3)−H Arylation of Free Aliphatic Acid

(2019) Pravas Dolui et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pt II ‐Catalyzed Hydroxylation of Terminal Aliphatic C(sp 3 )−H Bonds with Molecular Oxygen

(2019) Michiel Janssen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Direct β-C(sp3)–H Acetoxylation of Aliphatic Carboxylic Acids

(2019) Kiron K. Ghosh et al.   ORGANIC LETTERS

Sterically Controlled Late-Stage C–H Alkynylation of Arenes

(2019) Arup Mondal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct C(sp3)–H Activation of Carboxylic Acids

(2019) Alexander Uttry et al.   SYNTHESIS-STUTTGART

Lactonization as a general route to β-C(sp3)–H functionalization

(2019) Zhe Zhuang et al.   NATURE

Directing-Group-mediated C−H-Alkynylations

(2018) Lucien D. Caspers et al.   Chemistry-An Asian Journal

Pd(II)-Catalyzed Enantioselective C(sp3)–H Arylation of Free Carboxylic Acids

(2018) Peng-Xiang Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Enabled β-C(sp3)–H Olefination of Free Carboxylic Acids

(2018) Zhe Zhuang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Direct Pd-Catalyzed β-C(sp3)–H Activation of Carboxylic Acids

(2018) Manuel van Gemmeren et al.   SYNLETT

A Simple Aliphatic Diamine Auxiliary for Palladium-Catalyzed Arylation of Unactivated β-C(sp3)-H Bonds

(2018) Jiang Lou et al.   ADVANCED SYNTHESIS & CATALYSIS

A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry

(2018) Carlo Sambiagio et al.   CHEMICAL SOCIETY REVIEWS

PdII -Catalyzed Enantioselective C(sp3 )−H Activation/Cross-Coupling Reactions of Free Carboxylic Acids

(2018) Liang Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd(II)-Catalyzed Enantioselective C(sp3)–H Borylation

(2017) Jian He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Formation of α-chiral centers by asymmetric β-C(sp 3 )–H arylation, alkenylation, and alkynylation

(2017) Qing-Feng Wu et al.   SCIENCE

Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation

(2017) Liang Zhu et al.   Nature Communications

A Simple and Versatile Amide Directing Group for C−H Functionalizations

(2016) Ru-Yi Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carboxylic Acids as Directing Groups for C−H Bond Functionalization

(2016) Martin Pichette Drapeau et al.   CHEMISTRY-A EUROPEAN JOURNAL

Silver-Free Palladium-Catalyzed sp3 and sp2 C–H Alkynylation Promoted by a 1,2,3-Triazole Amine Directing Group

(2016) Xiaohan Ye et al.   ORGANIC LETTERS

Nickel-Catalyzed Oxidative Coupling of Unactivated C(sp3)–H Bonds in Aliphatic Amides with Terminal Alkynes

(2016) Fei-Xian Luo et al.   ORGANOMETALLICS

Cobalt-Catalyzed Cyclization of Aliphatic Amides and Terminal Alkynes with Silver-Cocatalyst

(2015) Jitan Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of β-alkynyl α-amino acids via palladium-catalyzed alkynylation of unactivated C(sp3)-H bonds

(2015) Bo Wang et al.   Science China-Chemistry

Transition metal-catalyzed C–H bond functionalizations by the use of diverse directing groups

(2015) Zhengkai Chen et al.   Organic Chemistry Frontiers

Palladium Nanoparticle-Catalyzed Direct Ethynylation of Aliphatic Carboxylic Acid DerivativesviaC(sp3)H Bond Functionalization

(2014) Mohammad Al-Amin et al.   ADVANCED SYNTHESIS & CATALYSIS

Palladium-Catalyzed Stereoretentive Olefination of Unactivated C(sp3)–H Bonds with Vinyl Iodides at Room Temperature: Synthesis of β-Vinyl α-Amino Acids

(2014) Bo Wang et al.   ORGANIC LETTERS

Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups

(2013) Guy Rouquet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(0)-Catalyzed Alkynylation of C(sp3)–H Bonds

(2013) Jian He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

On the Interpretation of Deuterium Kinetic Isotope Effects in CH Bond Functionalizations by Transition-Metal Complexes

(2012) Eric M. Simmons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrophilic alkynylation: the dark side of acetylene chemistry

(2012) Jonathan P. Brand et al.   CHEMICAL SOCIETY REVIEWS

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synergistic Palladium-Catalyzed C(sp3)H Activation/C(sp3)O Bond Formation: A Direct, Step-Economical Route to Benzolactones

(2011) Petr Novák et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Teratogenic Potencies of Valproic Acid Derivatives and Their Effects on Biological End-points are Related to Changes in Histone Deacetylase and Erk1/2 Activities

(2011) Kamil Gotfryd et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Palladium-Catalyzed Direct Ethynylation of C(sp3)–H Bonds in Aliphatic Carboxylic Acid Derivatives

(2011) Yusuke Ano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Formal Inverse Sonogashira Reaction: Direct Alkynylation of Arenes and Heterocycles with Alkynyl Halides

(2010) Alexander S. Dudnik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Potent neuroprotective effects of novel structural derivatives of valproic acid: Potential roles of HDAC inhibition and HSP70 induction

(2010) Yan Leng et al.   NEUROSCIENCE LETTERS

Palladium-Catalyzed Direct Alkynylation of C−H Bonds in Benzenes

(2009) Mamoru Tobisu et al.   ORGANIC LETTERS

Efficient construction of therapeutics, bioconjugates, biomaterials and bioactive surfaces using azide–alkyne “click” chemistry☆

(2008) J LUTZ et al.   ADVANCED DRUG DELIVERY REVIEWS