Small-Molecule Inhibitors of the Type III Secretion System

Derivative of plant phenolic compound inhibits the type III secretion system ofDickeya dadantiivia HrpX/HrpY two-component signal transduction and Rsm systems

(2014) Yan Li et al.   MOLECULAR PLANT PATHOLOGY

Discovery of Plant Phenolic Compounds That Act as Type III Secretion System Inhibitors or Inducers of the Fire Blight Pathogen, Erwinia amylovora

(2013) Devanshi Khokhani et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Structure and Biophysics of Type III Secretion in Bacteria

(2013) Srirupa Chatterjee et al.   BIOCHEMISTRY

Synthesis and Bioactivity of Novel Inhibitors for Type III Secretion System ofPseudomonas aeruginosaPAO1

(2013) Chengfang Zhang et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Anti-PcrV antibody in cystic fibrosis: A novel approach targetingPseudomonas aeruginosaairway infection

(2013) Carlos E. Milla et al.   PEDIATRIC PULMONOLOGY

Atomic model of the type III secretion system needle

(2012) Antoine Loquet et al.   NATURE

Small molecules aimed at type III secretion systems to inhibit bacterial virulence

(2012) Lun K. Tsou et al.   MedChemComm

Derivatives of Plant Phenolic Compound Affect the Type III Secretion System of Pseudomonas aeruginosa via a GacS-GacA Two-Component Signal Transduction System

(2011) Akihiro Yamazaki et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Three-Dimensional Model of Salmonella's Needle Complex at Subnanometer Resolution

(2011) O. Schraidt et al.   SCIENCE

Biogenesis, Regulation, and Targeting of the Type III Secretion System

(2011) Thierry Izoré et al.   STRUCTURE

Discovery and Characterization of Inhibitors of Pseudomonas aeruginosa Type III Secretion

(2010) D. Aiello et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The type III secretion injectisome, a complex nanomachine for intracellular ‘toxin’ delivery

(2010) Guy R. Cornelis   BIOLOGICAL CHEMISTRY

Small Molecule Inhibitors of LcrF, a Yersinia pseudotuberculosis Transcription Factor, Attenuate Virulence and Limit Infection in a Murine Pneumonia Model

(2010) L. K. Garrity-Ryan et al.   INFECTION AND IMMUNITY

A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium

(2010) Kyota Kimura et al.   JOURNAL OF ANTIBIOTICS

Anti-virulence strategies to combat bacteria-mediated disease

(2010) David A. Rasko et al.   NATURE REVIEWS DRUG DISCOVERY

Topology and Organization of the Salmonella typhimurium Type III Secretion Needle Complex Components

(2010) Oliver Schraidt et al.   PLoS Pathogens

Tethered thiazolidinone dimers as inhibitors of the bacterial type III secretion system

(2009) Toni Kline et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Guadinomines, Type III Secretion System Inhibitors, Produced by Streptomyces sp. K01-0509

(2009) Masato Iwatsuki et al.   JOURNAL OF ANTIBIOTICS

Guadinomines, Type III Secretion System Inhibitors, Produced by Streptomyces sp. K01-0509

(2009) Masato Iwatsuki et al.   JOURNAL OF ANTIBIOTICS

N-Hydroxybenzimidazole Inhibitors of the Transcription Factor LcrF inYersinia: Novel Antivirulence Agents

(2009) Oak K. Kim et al.   JOURNAL OF MEDICINAL CHEMISTRY

A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system

(2009) Thomas Spreter et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Plant Phenolic Compound p-Coumaric Acid Represses Gene Expression in the Dickeya dadantii Type III Secretion System

(2008) Y. Li et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

An Inhibitor of Gram-Negative Bacterial Virulence Protein Secretion

(2008) Heather B. Felise et al.   Cell Host & Microbe

Antivirulence as a new antibacterial approach for chemotherapy

(2008) Sonia Escaich   CURRENT OPINION IN CHEMICAL BIOLOGY

Identification and Characterization of a Novel Type III Secretion System in trh-Positive Vibrio parahaemolyticus Strain TH3996 Reveal Genetic Lineage and Diversity of Pathogenic Machinery beyond the Species Level

(2008) N. Okada et al.   INFECTION AND IMMUNITY

Virulence blockers as alternatives to antibiotics: type III secretion inhibitors against Gram-negative bacteria

(2008) P. Keyser et al.   JOURNAL OF INTERNAL MEDICINE

Substituted 2-Imino-5-arylidenethiazolidin-4-one Inhibitors of Bacterial Type III Secretion

(2008) Toni Kline et al.   JOURNAL OF MEDICINAL CHEMISTRY

The biology and future prospects of antivirulence therapies

(2007) Lynette Cegelski et al.   NATURE REVIEWS MICROBIOLOGY